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At Home COVID 19 Antigen Testing and Vaccine Update with Harvard Professor Michael Mina, MD

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  • At Home COVID 19 Antigen Testing and Vaccine Update with Harvard Professor Michael Mina, MD

    1:1:37

    Professor Michael Mina, MD answers key questions about at-home COVID 19 testing and coronavirus vaccines:
    0:00 We need a new testing strategy and at home rapid tests have advantages to PCR
    2:49 What other countries are using rapid antigen paper COVID-19 tests?
    3:25 Rapid decline of COVID-19 spread in Slovakia with paper antigen COVID 19 tests
    3:48 At home coronavirus tests are an intervention most people actually want (unlike distancing, shutdowns, etc.)
    6:21 FDA barrier to rapid at home COVID 19 tests
    6:40 The sensitivity of at-home tests to capture someone who is infectious with COVID 19 is 95-99%
    6:53 Simple ways to address false positives
    7:45 Manufacturing capacity needed for 10-20 million paper strip tests per day
    8:17 Dr. Mina’s discussions with various US leaders and elected officials about at home tests
    8:41 Dr. Fauci on at home coronavirus tests
    9:21 Who’s job is it to make rapid at home tests a reality?
    12:07 FDA approves the first at home SARS-CoV-2 test (made by Lucira), but will it be useful?
    15:35 New York Times article with a misleading title about rapid antigen tests
    16:09 PCR vs antigen tests are useful for completely different purposes
    20:32 Capturing the contagious window of COVID-19 with testing (the viral dynamics and the Ct values of SARS CoV 2)
    28:14 CDC estimates that over half of COVID-19 spread is asymptotic or pre-symptomatic
    31:05 Are any test manufactures collaborating on COVID-19 testing in the US (and using confirmatory tests)?
    36:17 What rapid COVID-19 have been approved in the US or outside the US that are suitable for a self test?
    36:46 Abbott Binax Now Test
    37:11 Abbott Panbio Test
    37:48 Roche SD Biosensor COVID-19 Test
    38:00 AccessBio Antigen Test
    38:32 E25Bio Rapid COVID-19 Test
    40:18 What entity should oversee at home COVID-19 screening tools? The FDA? CDC? a new entity?
    45:52 The (relatively small) expense of at home COVID-19 testing
    48:53 Practical testing tips for the testing services we have available now?
    54:05 Common misconceptions about rapid COVID-19 testing
    56:15 Will a viable coronavirus vaccine diminish the need for at home testing?
    57:09 Concerns about COVID 19 vaccine efficacy including plasmablast response
    1:00:00 Easier to adjust a paper test than a vaccine
    1:01:10 Parting words and how to learn more about rapid tests

    Michael Mina, MD, Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Assoc. Medical Director in Clinical Microbiology in the Department of Pathology at Brigham and Women’s Hospital, Harvard Medical School
    Dr. Mina’s full bio:

    The volunteer-based rapid test advocacy website that Dr. Mina is the director of:
    (a great place to learn more about rapid at-home tests or help advocate for them)

    Interviewer:

    Kyle Allred
    Physician Assistant
    MedCram.com Producer and Co-Founder
    Contact: customers@medcram.com


    LINKS FROM THIS INTERVIEW:

    Science Advances: Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening (Dr. Mina is a co-author) |

    Economic Benefits of COVID-19 Screening Tests (Dr. Mina is a co-author) |

    Time: How We Can Stop the Spread of COVID-19 By Christmas (by Dr. Michael Mina) |

    New York Times: A Rapid Virus Test Falters in People Without Symptoms, Study Finds |

    Worldometer: Slovakia COVID-19 Data:

    CDC |

    FDA |

    Previous MedCram Interview with Dr. Michael Mina on COVID-19Testing:

    Fast Company: Slovakia tested almost everyone in the country and ‘broke the curve’ |

    Dr. Mina's Twitter |

    TWiV 640 |

    MedCram: COVID-19 Rapid Tests Demo & Q/A with E25Bio Co-Founder |


    THE MEDCRAM WEBSITE:

    MedCram is a leader in online medical education. Our videos are utilized by thousands of clinicians and medical schools, PA programs, NP, RN, RT, and other professional programs. We offer over 60 medical topics and 50 hours of CME/CEs for medical professionals.

    Learn more:

    MedCram videos are for education and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #RapidTestsNow

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  • Rapid Coronavirus Testing - At HOME with Dr. Michael Mina

    1:7:07

    Michael Mina, MD, PhD responds to questions about how cheap (approx. $1), at-home, COVID-19 tests (results in 15 minutes) could be utilized to dramatically slow the spread of this pandemic (and open up schools etc. in a faster and safer way).

    Dr. Mina is an Assistant Professor of Epidemiology at the Harvard T.H Chan School of Public Health and a core member of the Center for Communicable Disease Dynamics. Dr. Mina's research has demonstrated that the sensitivity of these simple daily quick tests (the technology already exists) is high enough to detect the vast majority of infectious COVID-19 and could be utilized frequently at home with a nasal or saliva sample.


    LINKS / REFERENCES:

    Please watch MedCram Update 98 for context on Dr. Mina's research and ideas:
    We read your comments (from Update 98, and at MedCram.com) for COVID testing questions to ask Dr. Mina.

    Michael Mina, MD, Ph.D.'s bio:

    Dr. Mina's New York Times article about a new COVID-19 testing paradigm:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    Article featuring Dr. Mina's ideas published in Harvard Magazine on August 3, 2020

    TWiV 640: Test often, fast turnaround, with Michael Mina:

    Follow Dr. Mina on Twitter:

    Thanks for joining the event and please spread the word to friends and colleagues.

    A big thanks to Dr. Michael Mina for spending an hour with us.

    GET INVOLVED

    If you're seeking templates and streamlined ways to contact your governor and representatives in Congress about daily quick tests / rapid COVID 19 testing please visit the volunteer-based website that Dr. Mina is the director of.

    #RapidTestsNow #COVID19 #DailyQuickTest

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  • How to Fix COVID-19 Testing Q/A with Dr. Michael Mina: At Home Daily Quick Tests

    1:8:57

    Dr. Michael Mina from the Harvard T.H Chan School of Public Health answer questions about how cheap (approx. $1), at-home, COVID-19 tests (results in 15 minutes) could be utilized to dramatically slow the spread of this pandemic (and open up schools etc. in a faster and safer way).

    Dr. Mina's research has shown that the sensitivity of these daily quick tests (the technology already exists) is high enough to detect the vast majority of infectious COVID-19 and could be utilized frequently at home. These antigen tests only require a nasal or saliva sample.

    We've read your comments (from Update 98, and at MedCram.com) for COVID testing questions to ask Dr. Mina. Please watch MedCram Update 98 for context on Dr. Mina's work:

    Article featuring Dr. Mina's ideas published in Harvard Magazine on August 3, 2020

    Dr. Mina's New York Times article about a new COVID-19 testing paradigm:

    Dr. Mina's research paper (pre-print):

    Michael Mina, MD, Ph.D.'s bio:

    Follow Dr. Mina on Twitter:

    Thanks for joining the event and please spread the word to friends and colleagues.


    GET INVOLVED

    If you're seeking templates and streamlined ways to contact your governor and representatives in Congress about rapid COVID 19 testing / daily quick tests please visit
    (thanks to Chris Said for making this site)

    #DailyQuickTest #RapidTestsNow #COVID19

  • COVID 19 Vaccine Update with Professor Michael Mina, MD: Safety, Efficacy, Distribution, Trials

    8:42

    Harvard professor and epidemiologist Michael Mina MD, Ph.D. is back to give a COVID 19 Vaccine Update including:
    00:00 Attention to vaccine safety in phase one, two, and three trials
    00:21 Mild side effects from vaccines observed in phase 1 and 2 trials
    00:32 Awareness of fringe effects when the vaccine is introduced to thousands or millions
    00:59 Post-market surveillance of adverse effects vs. coincidence and confounding
    01:31 Ensuring efficacy - new territory with a coronavirus vaccine
    01:50 Sterilizing immunity
    02:06 Relatively weak immune response from coronaviruses vs severity
    02:29 Polio and measles vaccines create robust immunity
    02:59 New technology being used in some SARS-CoV-2 vaccines
    03:47 Cautious optimism about the efficacy of vaccines
    04:02 Herd immunity
    04:43 Who is going to get the COVID-19 vaccine first? Which countries?
    05:15 Medical professionals likely the first to receive vaccines
    06:02 Will COVID 19 vaccines block transmission and spread?
    06:10 Should kids get the vaccine?
    06:37 How well will vaccines work in the elderly and immunocompromised?
    07:46 How quickly can the COVID vaccines get distributed? By the end of this year?

    MedCram has no financial disclosures related to any medical products or vaccines, and from our understanding, Dr. Mina does not either.

    Michael Mina, MD Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    OTHER MEDCRAM VIDEOS FEATURING DR. MICHAEL MINA:

    COVID-19 Update 98 featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    Interview with Dr. Mina on frequent rapid paper strip COVID 19 testing: Dr. Mina is the director of where you can get more info about at-home COVID 19 screening


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.


    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #SARSCOV2 #Science

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  • At-Home Tests for COVID-19: Should We Wait Until Rapid Tests Rival PCR?

    2:14

    Harvard professor and epidemiologist Michael Mina, MD, PhD, responds to questions about inexpensive paper strip COVID 19 tests. Should we wait until these rapid paper tests are almost as sensitive as the gold standard PCR COVID-19 test? How important is sensitivity in determining who is contagious with COVID 19?

    Michael Mina, MD Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:

    Dr. Mina, Kyle Allred, Dr. Seheult, and MedCram have no financial disclosures related to this topic. We have a keen interest in curbing this pandemic and safely re-opening schools and our economy.


    MORE VIDEOS AND RESOURCES ON AT-HOME COVID 19 SCREENING TESTS:

    Dr. Michael Mina is the director (on a volunteer basis) of where you can get more info and streamlined ways to contact your governor and representatives in Congress about at-home COVID 19 screening

    See our previous MedCram videos that have featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus.

    A 3-minute explainer video on inexpensive at-home rapid screening tests by MedCram:

    A video summary and highlights of Dr. Mina's research and ideas in our MedCram COVID 19 Update 98:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    A short explainer video on daily quick tests produced by Dr. Allen:

    Summary Article Featured in the Atlantic about Inexpensive Rapid Testing:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:

    Visit MedCram.com for over 100 coronavirus pandemic updates including sensitivity vs specificity, covid 19 tests, diagnosis and treatment, and many more topics.

    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #rapidtestsnow #dailyquicktest

  • At Home Rapid COVID 19 Tests and False Positives

    3:41

    Harvard professor and epidemiologist Michael Mina, MD responds to the idea that inexpensive at-home coronavirus tests would produce too many false positives to be useful as a screening tool to curb the pandemic. False positives occur when someone tests positive but is not infected with SARS-CoV-2 that causes COVID-19.

    See our previous MedCram videos that have featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus.

    Dr. Mina, Kyle Allred, Dr. Seheult, and MedCram have no financial disclosures related to this topic. We have a keen interest in curbing this pandemic and safely re-opening schools and our economy.

    Michael Mina, MD Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:

    MORE VIDEOS AND RESOURCES ON AT-HOME COVID 19 SCREENING TESTS:

    Dr. Mina is the director (on a volunteer basis) of where you can get more info and streamlined ways to contact your governor and representatives in Congress about at-home COVID 19 screening

    A 3-minute explainer video on inexpensive at-home rapid screening tests by MedCram:

    A video summary and highlights of Dr. Mina's research and ideas in our MedCram COVID 19 Update 98:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    A short explainer video on daily quick tests produced by Dr. Allen:

    Summary Article Featured in the Atlantic about Inexpensive Rapid Testing:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:


    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #rapidtestsnow #dailyquicktest

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  • Herd Immunity and Effects: At Home Rapid COVID 19 Testing

    2:47

    Harvard professor and epidemiologist Michael Mina, MD, PhD, describes herd immunity in the context of herd effects and responds to the question: what if some people don't comply with at-home COVID-19 testing or stay home if they test positive?

    Michael Mina, MD Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:

    We have no financial disclosures related to any medical products. We have a strong interest in curbing this pandemic and safely re-opening schools and our economy.

    Other Q/A videos with Dr. Michael Mina on inexpensive quick paper antigen tests for COVID-19:

    Paper Strip Tests for COVID-19: Should We Wait Until They Rival PCR Tests?

    Are Antigen Paper Tests for COVID 19 Accurate Enough?

    False Positives and COVID 19 Rapid Tests:


    MORE VIDEOS AND RESOURCES ON AT-HOME COVID 19 SCREENING TESTS:

    Dr. Michael Mina is the director (on a volunteer basis) of where you can get more info and streamlined ways to contact your governor and representatives in Congress about at-home COVID 19 screening

    See our previous MedCram videos that have featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus.

    A 3-minute explainer video on inexpensive at-home rapid screening tests by MedCram:

    A video summary and highlights of Dr. Mina's research and ideas in our MedCram COVID 19 Update 98:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    A short explainer video on daily quick tests produced by Dr. Allen:

    Summary Article Featured in the Atlantic about Inexpensive Rapid Testing:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:

    Visit MedCram.com for over 100 coronavirus pandemic updates including sensitivity vs specificity, covid 19 tests, diagnosis and treatment, and many more topics.

    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #rapidtestsnow #dailyquicktest

  • COVID-19 Rapid Tests Demo & Q/A with E25Bio Co-Founder

    23:38

    Simple and cheap COVID-19 tests that provide rapid results (15 min.) have been called a possible game-changer to curb the pandemic and allow schools and stores to open safely. Our guest today is Bobby Brooke Herrera, Ph.D. - the Co-Founder of a small company based in Massachusetts called E25Bio. Back on February 26, 2020, E25Bio had its inexpensive COVID-19 antigen test developed, but his company has run into numerous hurdles - lack of guidance and reasonable standards from the FDA, limited federal investment into public health testing strategies, and challenging pathways to production and distribution.

    Dr. Herrera gives a demo of their simple test that requires a simple nasal swab, plastic tube, a paper strip, and no additional processing. He also discusses how tests like this could be distributed and utilized to quickly curtail the spread of COVID-19. (This video was recorded August 12, 2020).

    LINKS / REFERENCES:

    More about Dr. Bobby Brooke Herrera - Co-Founder of E25Bio |

    MedCram Update 98 for context on rapid daily quick tests and Dr. Mina's research |

    5-Minute Sharable Video About At-Home Rapid Tests |

    Boston Globe Article about E25Bio |

    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - COVID-19 Pandemic Update 101: T Cell Immunity vs. Antibodies & Prior Exposure to Other Coronaviruses
    - At Home, Cheap, COVID-19 Tests with Results in 15 Minutes: How to Fix Testing with Dr. Michael Mina
    - Coronavirus Pandemic Update 100: Interferon Beta COVID-19 Treatment, and a Retrospective
    - Coronavirus Pandemic Update 99: Long Haulers - Lingering & Long-Term Symptoms After COVID-19
    - Coronavirus Pandemic Update 98: At Home COVID-19 Testing - A Possible Breakthrough
    - Coronavirus Pandemic Update 97: Vitamin D & COVID-19 Immunity, The Endothelium, & Deficiencies
    - Coronavirus Pandemic Update 96: RNA Vaccine; Ivermectin; von Willebrand Factor and COVID-19
    - Coronavirus Pandemic Update 95: Widespread Clotting on Autopsy; New COVID-19 Prognostic Data
    - Coronavirus Pandemic Update 94: Inhaled Steroids COVID-19 Treatment; New Pneumonia in Kazakhstan?
    - Coronavirus Pandemic Update 93: Antibodies, Immunity, & Prevalence of COVID-19 - New Data from Spain
    - Coronavirus Pandemic Update 92: Blood Clots & COVID-19 - New Research & Potential Role of NAC
    - Coronavirus Pandemic Update 91: Remdesivir Pricing & Disparities in Drug Availability

    All coronavirus updates are at MedCram.com (including more on vaccine developments, rapid COVID-19 testing, paper COVID 19 antigen tests, COVID 19 antibody tests, coronavirus daily quick tests, coronavirus news, COVID test, peer-reviewed research, and more).
    We offer many other medical topics (ECG Interpretation, asthma, acute kidney injury, pulmonary embolism, myocardial infarction, hypertension, DKA, influenza, measles, mechanical ventilation, etc.) at our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. We also offer over 40 hours of CME and CEU credits. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #RapidTestsNow #DailyQuickTest

  • The Coronavirus Pandemic: The Latest on Variants and Rapid Testing

    47:33

    What are the implications that five COVID-19 variants that appear to spread faster than other variants are now circulating in the United States? How might continuing vaccination rollouts, as well as the anticipated availability of an increasing number of over-the-counter at-home tests, factor into controlling further spread? And what is the latest on COVID-19 vaccine development and access? In this Q&A, Harvard Chan epidemiologist Michael Mina and The World's Elana Gordon take your questions.

    Presented jointly by The Forum at the Harvard T.H. Chan School of Public Health and The World from PRX & GBH.

  • x
  • COVID 19 Vaccine Deep Dive: Safety, Immunity, RNA Production,

    34:29

    Professor Shane Crotty, PhD joins MedCram to answer a series of COVID vaccine questions including what are the chances of long-term side effects? How safe is RNA vaccine (i.e. Pfizer / BioNTech and Moderna Vaccines) technology? How long does mRNA from a vaccine stay in our cells? What else goes in vaccines? How long does immunity last? Why are T-Cells so important? Why does Pfizer's vaccine need to stay SO cold?

    Shane Crotty, PhD is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Professor Crotty also has an academic appointment with the University of California San Diego. See his full bio here:
    Professor Crotty on Twitter:

    Interviewer: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com

    See our new interview with Prof. Crotty on how virus mutations (UK variant and S. African variant) may be impacting COVID-19 transmission and vaccine efficacy.

    Research referenced in this video from Prof. Crotty and his team was published Jan. 6, 2021, in the prestigious Journal Science:

    New York Times article highlighting Prof. Shane Crotty's research:

    00:00 Introducing Prof. Shane Crotty's Research
    0:35 How long does COVID-19 immune memory last?
    0:57 The three primary aspects of immune memory: antibodies, killer T cells, and helper T cells
    2:25 The anatomy (protein makeup) of SARS-CoV-2
    3:02 Why is spike protein the primary target?
    5:17 Could a mutation allow SARS-CoV-2 to infect without spike protein?
    7:02 Utilizing lipid nanoparticles to deliver mRNA and the role of RNA normally
    9:52 What human cells does an RNA vaccine go into?
    10:36 How long does mRNA from a vaccine stay in human cells?
    11:44 What else goes in vaccines besides mRNA and lipid nanoparticles? Any preservatives or adjuvants?
    12:30 Why are adjuvants used in many vaccines?
    14:08 Protein production from mRNA
    15:00 Why utilize the extra step of mRNA to code for protein antigens?
    17:28 Are mRNA vaccines the future of vaccine development?
    19:18 Any chance for mRNA to enter our cells' nucleus?
    20:55 The immune response to a coronavirus vaccine
    23:17 Expected symptoms from immune response to a vaccine vs. vaccine side effects
    25:50 Should people who've had COVID-19 get vaccinated?
    27:27 Immunity from COVID vaccine vs. a natural infection
    28:30 Why does the Pfizer vaccine need to be stored so cold?
    29:04 What would you say to a family member who is nervous about a rushed vaccine and RNA technology?
    32:37 What about the possibility of long term side effects from RNA vaccines?
    33:30 What's next for Shane Crotty's research team?

    (This video was recorded on December 16, 2020).

    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon!


    PREVIOUS / RECENT MEDCRAM COVID-19 INTERVIEWS:

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing and Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including more videos on the Pfizer vaccine, Moderna vaccines, BioNTech vaccine, vaccine side effects, COVID 19 vaccine mechanism, AstraZeneca Oxford coronavirus vaccine, side effects of COVID 19 vaccine, COVID 19 treatments, and more):

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website and CME for clinicians.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavaccine

  • New Approaches to Covid-19: Rapid Testing, Herd Immunity, and the Role of Narrative

    1:29:33

    In this UCSF Medical Grand Rounds, we discuss three new approaches for addressing Covid-19 that are gaining traction. Michael Mina, of the Harvard T.H. Chan School of Public Health, talks about the evidence supporting the move from highly sensitive PCR-based viral tests to more rapid, cheaper, and less sensitive tests. Trevor Bedford, of the University of Washington and the Fred Hutchinson Cancer Research Center, describes his theory that, in hard-hit regions, we may be closer to herd immunity than previously thought. Finally, Emily Silverman and Ashley McMullen, both of UCSF, discuss the role of the narrative in deepening our understanding of Covid by giving voice to clinicians and patients. The session is moderated by UCSF Department of Medicine chair Bob Wachter.

    Program
    Bob Wachter: Introduction
    00:05:53 – Rapid Testing: Michael Mina, Assistant Professor, Epidemiology, Harvard T.H. Chan School of Public Health
    00:23:58 – Q&A
    00:38:48 – Herd Immunity: Trevor Bedford, Affiliate Associate Professor, Epidemiology and Genome Sciences, University of Washington; Associate Professor, Fred Hutchinson Cancer Research Center
    00:52:43 – Q&A
    01:05:36 – The Role of Narrative: Emily Silverman, Assistant Professor, Division of Hospital Medicine, ZSFG, UCSF; Founder and Host, The Nocturnists
    01:19:18 – The Role of Narrative: Ashley McMullen, Assistant Professor, Division of General Internal Medicine, San Francisco VA Health Care System, UCSF; Host, Black Voices in Healthcare
    01:25:44 – Q&A
    01:28:16 – Bob Wachter: Closing

    Learn more about the Nocturnists here:



     See previous Covid-19 Medical Grand Rounds:
    • August 6: A Conversation with Ashish Jha

    • July 30: An Update on Covid-19 Testing, Treatments, and Vaccines

    • July 23: Covid-19: Reports of New Surges from Miami, Atlanta, Houston, and UCSF

    • July 16: How the Virus Gets in and How to Block It: Aerosols, Droplets, Masks, Face Shields, and More


    See all UCSF Covid-19 grand rounds, which have been viewed more than 750,000 times, here:

  • Ct Values: How They Should be Assessed for SARS CoV 2

    6:14

    Professor Michael Mina, MD explains how the viral dynamics of SARS-CoV-2, the infectious window, and how Ct values (cycle threshold values) should be interpreted from PCR SARS CoV 2 testing. And how Ct values on a logarithmic scale can be misinterpreted.

    See the full interview with Professor Michael Mina, MD on rapid antigen testing for COVID 19 here:

    Michael Mina, MD, Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology (molecular diagnostics) in the Department of Pathology at Brigham and Women’s Hospital, Harvard Medical School
    Dr. Mina’s full bio:

    The volunteer-based rapid test advocacy website that Dr. Mina is the director of: (a great place to learn more about rapid antigen tests for COVID-19)

    Interviewer:

    Kyle Allred
    Physician Assistant
    MedCram.com Producer and Co-Founder
    Contact: customers@medcram.com



    THE MEDCRAM WEBSITE:

    MedCram is a leader in online medical education. Our videos are utilized by thousands of clinicians and medical schools, PA programs, NP, RN, RT, and other professional programs. We offer over 60 medical topics and 50 hours of category 1 CME / CEs for medical professionals. See new topics and more about ct value in COVID 19.

    Learn more:

    MedCram videos are for education and NOT intended to replace recommendations from your doctor.

    ----------------------
    In this video, Michael Mina, MD illustrates Ct Values (Cycle threshold values), Rapid antigen COVID tests (including the availability of an antigen test for COVID 19) vs. PCR tests for coronavirus.
    #COVID19 #SARSCoV2 #CtValues

  • COVID-19 Pandemic Update 101: T Cell Immunity vs. Antibodies & Prior Exposure to Other Coronaviruses

    16:26

    The relationship between antibodies for the novel coronavirus (SARS-CoV-2) and immunity, vaccine efficacy, and spread of COVID-19 has received significant attention. Dr. Seheult is back to illustrate why T cells have received less attention than antibodies, but may be more important to long term immunity from COVID-19. Dr. Seheult also discusses how previous infections with common coronaviruses may provide some immunity to SARS-CoV-2, and the hypothesis that reducing the inoculum (initial dose) of SARS-CoV-2 might result in less symptom severity (This video was recorded August 10, 2020).

    LINKS / REFERENCES:

    5-Minute Sharable Video About At-Home Rapid Tests |

    Johns Hopkins Tracker |

    Worldometer |

    CNBC |

    Clinical Infectious Diseases |

    Cell |

    Washington Post |

    Nature |

    Journal of General Internal Medicine (Reducing inoculum) |

    CDC |

    NPR |

    New York Times |


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    PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - At Home, Cheap, COVID-19 Tests with Results in 15 Minutes: How to Fix Testing with Dr. Michael Mina
    - Coronavirus Pandemic Update 100: Interferon Beta COVID-19 Treatment, and a Retrospective
    - Coronavirus Pandemic Update 99: Long Haulers - Lingering & Long-Term Symptoms After COVID-19
    - Coronavirus Pandemic Update 98: At Home COVID-19 Testing - A Possible Breakthrough
    - Coronavirus Pandemic Update 97: Vitamin D & COVID-19 Immunity, The Endothelium, & Deficiencies
    - Coronavirus Pandemic Update 96: RNA Vaccine; Ivermectin; von Willebrand Factor and COVID-19
    - Coronavirus Pandemic Update 95: Widespread Clotting on Autopsy; New COVID-19 Prognostic Data
    - Coronavirus Pandemic Update 94: Inhaled Steroids COVID-19 Treatment; New Pneumonia in Kazakhstan?
    - Coronavirus Pandemic Update 93: Antibodies, Immunity, & Prevalence of COVID-19 - New Data from Spain
    - Coronavirus Pandemic Update 92: Blood Clots & COVID-19 - New Research & Potential Role of NAC
    - Coronavirus Pandemic Update 91: Remdesivir Pricing & Disparities in Drug Availability

    All coronavirus updates are at MedCram.com (including the diagnosis, prevention, treatment, vaccine developments, dexamethasone, Rapid COVID-19 Testing, paper COVID 19 antigen tests, beta interferon (sometimes called interferon beta), vitamin D, SARS-CoV-2 antibody tests, coronavirus misinformation, covid 19 tests, peer-reviewed research, and more).
    We offer many other medical topics (ECG Interpretation, thrombosis, pulmonary embolism, myocardial infarction, hypertension, anticoagulation, DKA, acute kidney injury, influenza, measles, mechanical ventilation, etc.) at our website.


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    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Roger Seheult, MD
    Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
    Associate Professor at the University of California, Riverside School of Medicine

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

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    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #FOAMed

  • Infectious Disease and Microbiome Program Meeting: COVID-19 testing

    1:21

    April 10, 2020
    Broad Institute

    Infectious Disease and Microbiome Program Meeting:
    COVID testing: What went wrong, where we are now, and where we are going
    Broad Institute

    Michael Mina, MD, PhD

    Michael Mina is an Assistant Professor of Epidemiology and of Infectious Diseases at HSPH, an Associate Medical Director in the Department of Pathology at BWH, and an Associate Member of the Broad Institute.

    Copyright Broad Institute, 2020. All rights reserved.

  • Coronavirus Pandemic Update 104: COVID 19 Reinfection & Immunity

    8:53

    The first documented COVID 19 reinfection has been reported in Hong Kong verified by genetic sequencing. Dr. Seheult of explains the importance of this patient's symptoms (he was asymptomatic with the second infection) and how immunity to viruses typically builds over time with subsequent exposures or vaccines. Dr. Seheult also discusses comparisons to previous viruses such as smallpox that have caused large numbers of deaths among populations without any prior exposure. (This video was recorded August 26, 2020).

    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    New York Times |

    STAT |

    Michael Mina on Twitter |

    Wikipedia |

    Business Insider |

    Arizona State University B Cells vs T Cells |

    Dengue in Nature |


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


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    PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Pandemic Update 103: Convalescent Plasma Treatment & the FDA; College Campuses Close
    - At Home, Cheap, COVID-19 Tests with Results in 15 Minutes: How to Fix Testing with Dr. Michael Mina
    -Coronavirus Pandemic Update 102: COVID 19 vs. Influenza Symptoms; Sweden; Tocilizumab; Hawaii
    - COVID-19 Pandemic Update 101: T Cell Immunity vs. Antibodies & Prior Exposure to Other Coronaviruses
    - Coronavirus Pandemic Update 100: Interferon Beta COVID-19 Treatment, and a Retrospective
    - Coronavirus Pandemic Update 99: Long Haulers - Lingering & Long-Term Symptoms After COVID-19
    - Coronavirus Pandemic Update 98: At Home COVID-19 Testing - A Possible Breakthrough
    - Coronavirus Pandemic Update 97: Vitamin D & COVID-19 Immunity, The Endothelium, & Deficiencies
    - Coronavirus Pandemic Update 96: RNA Vaccine; Ivermectin; von Willebrand Factor and COVID-19
    - Coronavirus Pandemic Update 95: Widespread Clotting on Autopsy; New COVID-19 Prognostic Data
    - Coronavirus Pandemic Update 94: Inhaled Steroids COVID-19 Treatment; New Pneumonia in Kazakhstan?
    - Coronavirus Pandemic Update 93: Antibodies, Immunity, & Prevalence of COVID-19 - New Data from Spain
    - Coronavirus Pandemic Update 92: Blood Clots & COVID-19 - New Research & Potential Role of NAC

    All coronavirus updates are at MedCram.com (including COVID 19 diagnosis, prevention, treatment, vaccine developments, COVID reinfection (coronavirus re-infection) rapid COVID-19 Testing, paper COVID 19 antigen tests, beta interferon, and more).
    We offer many other medical topics (ECG Interpretation, thrombosis, pulmonary embolism, myocardial infarction, hypertension, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Roger Seheult, MD
    Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
    Associate Professor at the University of California, Riverside School of Medicine

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Reinfection

  • Coronavirus Mutations and COVID 19 Vaccine Implications with Shane Crotty, PhD

    39:47

    Professor Shane Crotty, Ph.D. explains recent coronavirus mutations and how they might impact COVID 19 vaccines and transmission. COVID-19 research of Prof. Crotty and his team was published Jan. 6, 2021, in the prestigious Journal Science:

    Prof. Shane Crotty is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Prof. Crotty also has an academic appointment with the University of California San Diago. See his full bio here:
    Prof. Crotty on Twitter:

    Interviewer: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com


    TOPICS DISCUSSED IN THIS VIDEO INCLUDE:

    0:00 Intro
    0:08 SARS-CoV-2 / COVID 19 mutations (UK variant etc.) and implications for COVID-19 vaccines
    10:58 How to test if coronavirus variants can escape immunity
    12:28 How have mutations made this virus more transmissible?
    17:44 Could mutations make vaccines less than 50% effective?
    24:15 Possible changes to vaccine schedules (one dose, half dose)?
    35:34 Could alternate COVID-19 vaccine schedule make mutations more likely?
    38:29 What is next for Prof. Crotty and his team?

    (This video was recorded on January 5, 2021)

    PREVIOUS DISCUSSION WITH PROF. CROTTY (Dec 16, 2020):


    REFERENCES:

    Viral mutations may cause another ‘very, very bad’ COVID-19 wave, scientists warn (Science) |

    Vaccine Tracker (Bloomberg) |

    FDA Statement on Following the Auth. Dosing Schedules for COVID-19 Vaccines |

    S-variant SARS-CoV-2 is assoc. with sig. higher viral loads in samples tested by ThermoFisher TaqPath RT-QPCR (MedRxiv) |

    Human Leukocyte Antigen (HLA) System |

    UK reports new variant, termed VUI 202012/01 (GISAID)

    Covid-19 in South Africa: Scientists seek to understand new variant (BBC) |

    Mutation Allows Coronavirus to Infect More Cells. Scientists Urge Caution (NY Times) |

    The UK is delaying second vaccine shots and it’s proving controversial (CNBC)

    The receptor binding domain of the SARS-CoV-2 (News Medical Life Sciences) |

    NY Times article highlighting Prof. Shane Crotty's research:


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


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    PREVIOUS / RECENT MEDCRAM COVID-19 INTERVIEWS:

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing and Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including more on RNA vaccines, BioNTech vaccine, vaccine side effects, AstraZeneca Oxford coronavirus vaccine, side effects of COVID 19 vaccine, new strain of coronavirus, and more):

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website and CME for clinicians.


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    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavaccine

  • Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data

    12:31

    Professor Roger Seheult, MD breaks down important COVID 19 Updates including:
    - A new study on how an essential fatty acid (Linoleic Acid) may prevent SARS-CoV-2 binding
    - UK data suggests that COVID-19 cases are increasing exponentially as testing increases linearly
    - Johnson and Johnson paused their COVID-19 vaccine trial due to a possible adverse effect. (This video was recorded on October 13, 2020).

    Dr. Seheult is the co-founder and lead instructor at

    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein (Science) |

    Linoleic Acid: A Nutritional Quandary (Healthcare) |

    Californians hospitalized with COVID-19 at lowest level in 6 months (Los Angeles Times) |


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


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    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?
    - COVID 19 Update Update 106: Comorbidities and Excess Deaths; Bradykinin and Coronavirus
    - Coronavirus Pandemic Update 105: FDA Authorized Treatments; COVID 19 Vaccine Update
    - Coronavirus Pandemic Update 104: COVID 19 Reinfection & Immunity
    - Coronavirus Pandemic Update 103: Convalescent Plasma Treatment & the FDA; College Campuses Close
    - At Home, Cheap, COVID-19 Tests with Results in 15 Minutes: How to Fix Testing with Dr. Michael Mina

    All coronavirus updates are at MedCram.com (including vaccine COVID 19, Linoleic Acid and sars cov 2, n acetylcysteine, COVID data from the US vs UK, covid 19 prevention, covid vaccine, coronavirus vaccine, vitamin d covid 19, vitamin d deficiency, and more).
    We offer many other medical topics (ECG Interpretation, thrombosis, pulmonary embolism, myocardial infarction, hypertension, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Roger Seheult, MD
    Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
    Associate Professor at the University of California, Riverside School of Medicine

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • COVID 19 and Pregnancy: Vaccines, Fertility, & Breastfeeding with Dr. Viki Male

    27:39

    Dr. Victoria Male explains key issues related to COVID and pregnancy including coronavirus vaccine safety, fertility questions, breastfeeding, antibodies, and more. See more on the research related to these topics in Dr. Seheult's video here:

    Victoria Male, PhD is a Faculty of Medicine at Imperial College in London and Lecturer in Reproductive Immunology. Dr. Male's PhD was at the University of Cambridge on natural killer cells in human pregnancy. Full bio:

    Interviewer: Kyle Allred, Physician Assistant, Producer / Co-Founder of MedCram.com

    TOPICS IN THIS VIDEO INCLUDE:

    0:00 Interview Highlights
    0:21 What does pregnancy do to the immune system?
    1:31 Do COVID 19 vaccines impact fertility?
    3:08 COVID 19 fertility questions - how did the vaccine rumor start?
    5:16 COVID and pregnancy - disease severity and fertility
    6:31 Other viruses that impact fertility and pregnancy?
    8:41 Should pregnant women have been excluded from coronavirus vaccine trials?
    11:22 Can babies receive COVID-19 antibodies from breastmilk?
    12:19 5 types of human antibodies
    13:24 Are T cells transferred by breastfeeding? 4 key cells of immunity
    14:06 Should breastfeeding mothers get a COVID 19 vaccine?
    14:19 Should people trying to get pregnant get a COVID vaccine?
    15:06 COVID 19 prevention for pregnant women in the workplace
    16:15 Should pregnant women take a COVID 19 vaccine?
    16:53 First trimester pregnancies and COVID 19 - should they wait?
    18:01 Tips for optimizing immunity during pregnancy
    19:54 A perspective on balancing risks
    21:25 Dr. Viki Male's path to becoming a scientist
    24:58 Current research on natural killer cells in pregnancy
    25:50 Following Dr. Male's work
    26:20 FACS: Flow Assisted Cell Sorting

    (This video was recorded on February 12, 2021)

    REFERENCES:

    Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis (British Medical Journal) |

    Explainer on COVID19 Vaccination, Fertility and Pregnancy - Maintained by Dr. Male |

    Coronavirus Update with Anthony Fauci - February 3, 2021 (Jama Network) |

    I'm Pregnant. Should I get a COVID vaccine? A decision-making tool (UMass Medical School) |

    Dr. Male on Twitter:


    THE MEDCRAM WEBSITE:

    Visit us for videos on 60+ medical topics and CME / CEs for medical professionals:


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    Get notified of new videos by hitting the bell icon!


    RECENT MEDCRAM COVID-19 INTERVIEWS:

    Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna

    Ventilation & Filtration: Prevent COVID 19 + Optimize Health with Prof. Joe Allen

    Coronavirus Mutations and COVID 19 Vaccine Implications with Shane Crotty (SARS CoV 2 Variants)

    COVID 19 Q/A: Roger Seheult & John Campbell: Lessons Learned and a Look Ahead

    If You Get COVID 19: Optimize Immune System (Vitamin D, Monoclonal Antibodies, NAC, Quercetin etc.)

    COVID 19 Vaccine Deep Dive: Safety, Immunity, RNA Production, w Shane Crotty, PhD (Pfizer / Moderna)

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing & Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including over 100 COVID-19 updates and interviews and more on covid fertility, breastfeeding covid 19 antibodies, covid 19 vaccine fertility, covid pregnancy):

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website and CME for clinicians.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com

    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

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    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT medical advice or intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavirus

  • Mental Health and Wellness During a Pandemic - Dr. Peter Yellowlees

    35:26

    Dr. Yellowlees discusses strategies for optimal mental health and wellness during the COVID 19 pandemic, and tips for avoiding anxiety, depression, and social isolation

    Peter Yellowlees, MD is Professor of Psychiatry and Cheif Wellness Officer at UC Davis Health. He has published seven books and over 200 scientific articles and book chapters. Full bio here:

    Interviewer: Kyle Allred, Physician Assistant, Producer / Co-Founder of MedCram.com

    (This video was recorded on February 19, 2021)


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Introduction to Dr. Peter Yellowlees
    00:35 Mental health during COVID-19 pandemic: moral injury, burnout, anxiety and distress
    02:31 Specific stressors contributing to mental health issues
    05:07 Definition of “anxiety” and its role as a defense mechanism
    06:28 How poverty contributes to links between obesity/inactivity and depression/anxiety
    08:21 Is there a difference between mental health and wellness?
    10:06 Difference between “physical distancing” and “social distancing”
    12:08 How personality traits may or may not contribute to mental health during COVID-19 pandemic
    14:46 Setting boundaries, especially for parents and children
    16:20 How to support healthcare professionals and physicians
    18:39 Use of cell phones and mental health
    21:17 Tips for creating healthy interactions with the news and media
    21:54 Research and experience with virtual appointments and physician visits
    24:44 Techniques for gathering patients’ vital signs and information during virtual visits
    26:40 Silver linings of the COVID-19 pandemic
    27:30 What does a Chief Wellness Officer do?
    28:28 How gratitude leads to happiness and how to incorporate it into a pandemic
    30:46 What is “burnout?”
    33:07 Importance of hope amidst the COVID-19 pandemic


    REFERENCES:

    CBT-i Coach App |


    THE MEDCRAM WEBSITE:

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    RECENT MEDCRAM COVID-19 INTERVIEWS:

    COVID 19 and Pregnancy: Vaccines, Fertility, & Breastfeeding with Dr. Viki Male

    Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna

    Ventilation & Filtration: Prevent COVID 19 + Optimize Health with Prof. Joe Allen

    Coronavirus Mutations and COVID 19 Vaccine Implications with Shane Crotty (SARS CoV 2 Variants)

    COVID 19 Q/A: Roger Seheult & John Campbell: Lessons Learned and a Look Ahead

    If You Get COVID 19: Optimize Immune System (Vitamin D, Monoclonal Antibodies, NAC, Quercetin etc.)

    COVID 19 Vaccine Deep Dive: Safety, Immunity, RNA Production, w Shane Crotty, PhD (Pfizer / Moderna)

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing & Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including over 100 COVID-19 updates and interviews and more on COVID depression, COVID mental health, social anxiety, mental health COVID, and more):

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website and CME for clinicians.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com

    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

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    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT medical advice or intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #MentalHealth

  • Ventilation & Filtration: Prevent COVID 19 + Optimize Health

    43:13

    Harvard Prof. Joseph Allen explains how the air in our homes, workplaces, and schools is contributing to disease, poor mental function, and putting us at higher risk for COVID-19. The good news? Solutions can be as simple as opening a window.

    Joseph G. Allen is Associate Professor of Exposure Assessment Science at the Harvard T.H. Chan School of Public Health and the Director of the Harvard Healthy Buildings Program. See his full bio here:

    Interviewer: Kyle Allred, Physician Assistant, Producer / Co-Founder of MedCram.com

    TOPICS IN THIS VIDEO INCLUDE:

    0:00 Interview Highlights
    0:47 Introducing Prof. Joseph Allen
    1:58 Aerosols vs. droplets: is plexiglass helpful against COVID-19?
    3:12 Mask on in office building with barriers every 6 feet?
    4:11 Why such little recognition of ventilation and filtration for coronavirus?
    6:11 Simple strategies to improve ventilation and filtration at home, office, school
    7:59 Why air changes per hour is so important, healthy buildings, and sick building syndrome
    9:44 Air cleaners and best air purifiers for health and COVID 19 prevention
    11:43 Clean Air Delivery Rate (CADR) for HEPA filters, Best air purifier reviews
    14:10 Optimizing masks: type, fit, data
    17:06 Mask fitters and N95 fit testing
    18:25 Humidity and coronavirus
    20:56 Is airplane travel high risk for COVID 19?
    23:42 Portable CO2 monitors
    26:13 Ventilation and cognitive performance
    28:12 Design changes for better indoor health and performance
    29:23 Getting kids back to school for in-person learning
    33:22 How schools (and homes) can improve their air
    35:07 BPA free and chemical whack a mole
    41:29 Final thoughts from Prof. Allen - humans have become an indoor species

    (This video was recorded on January 15, 2021)

    REFERENCES:

    Healthy Buildings Website | (Harvard School of Public Health / J. Allen Et al.)

    5 Steps to Checking Ventilation in Classrooms |

    Air Cleaner Calculator | (Harvard- CU Boulder)

    Professor Allen’s Book: Healthy Buildings | (also available on Amazon.com)

    These toxic chemicals are everywhere — even in your body. And they won’t ever go away | (Joseph Allen - Washington Post)

    Inward and outward effectiveness of cloth masks, a surgical mask, and a face shield | (MedRxiv - Linsey C. Marr Et al.)

    An inexpensive mask “fitter” |

    Prof. Allen on Twitter:


    THE MEDCRAM WEBSITE:

    Visit us for videos on 60+ medical topics and CME / CEs for medical professionals:


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    Get notified of new videos by hitting the bell icon!


    PREVIOUS / RECENT MEDCRAM COVID-19 INTERVIEWS:

    Coronavirus Mutations and COVID 19 Vaccine Implications with Shane Crotty (SARS CoV 2 Variants)

    COVID 19 Q/A: Roger Seheult & John Campbell: Lessons Learned and a Look Ahead

    If You Get COVID 19: Optimize Immune System (Vitamin D, Monoclonal Antibodies, NAC, Quercetin etc.)

    COVID 19 Vaccine Deep Dive: Safety, Immunity, RNA Production, w Shane Crotty, PhD (Pfizer / Moderna)

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing & Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including over 100 COVID-19 updates and interviews):

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website and CME for clinicians.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com

    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

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    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT medical advice or intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #HealthyBuildings

  • x
  • How to Beat COVID-19 with At Home Rapid Testing by Michael Mina, MD

    5:34

    We've received your requests for a brief summary video (to share!) of Dr. Michael Mina's research and how inexpensive (approx. $1), at-home, COVID-19 tests (results in 15 minutes) could be utilized to dramatically slow the spread of this pandemic (and open up schools etc. in a faster and safer way).

    Dr. Mina is an Assistant Professor of Epidemiology at the Harvard T.H Chan School of Public Health and a core member of the Center for Communicable Disease Dynamics. Dr. Mina's research has demonstrated that the sensitivity (accuracy) of these simple saliva or swab paper daily quick tests (the technology already exists) is high enough to detect the vast majority of infectious #COVID19 and could be utilized frequently at home.


    2 INITIAL WAYS TO HELP:

    1) Please share this video with friends, colleagues, and elected officials. If possible, use the hashtag #RapidTestsNow or #DailyQuickTest

    2) For templates and streamlined ways to contact your governor and representatives in Congress about rapid COVID 19 testing, visit the volunteer-based website that Dr. Mina is the director of.


    LINKS / REFERENCES:

    For a more in-depth summary of Dr. Mina's research and ideas:

    Michael Mina, MD, Ph.D.'s bio:

    Dr. Mina's New York Times article about a new COVID-19 testing paradigm:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:

    Follow Dr. Mina on Twitter:

    More info and ways to contact your elected officials about antigen tests / rapid COVID tests:


    MORE READING:

    A Harvard Magazine article by Jonathan Shaw on August 3, 2020: Failing the Coronavirus-Testing Test has a nice summary of Dr. Mina's message

    Selected excerpts from that article:

    “At the moment, the United States has no semblance of public-health testing” says Michael Mina.

    Current tests for active infection with SARS-CoV-2 are highly sensitive—but most are given to suspected COVID-19 patients long after the infected person has stopped transmitting the virus to others. That means the results are virtually useless for public-health efforts to contain the raging pandemic. These PCR (polymerase chain reaction) tests, which amplify viral RNA to detectable levels, are used by physicians, often in hospital settings, to help guide clinical care for individual patients. In general, members of the public have not had access to such tests outside clinical settings, but even if they did, would find them too expensive for frequent use.

    The astounding realization is that all we’re doing with all of this testing is clogging up the testing infrastructure,” with results arriving a week or more after tests are administered, “and essentially finding people for whom we can’t even act because they are done transmitting, says Mina.

    “We need to change the whole script of what it means to test people,” he says. “In our country, we have always assumed that testing belongs in the clinical sphere, in the diagnostic sphere, and has to be run by laboratories or diagnosticians. The result is that we have a system for coronavirus testing…which is flailing, with raging outbreaks occurring.” What the country needs instead are rapid tests, widely deployed, so that infectious individuals can be readily self-identified and isolated, breaking the chain of transmission.

    So even though a saliva-based paper test wouldn’t register a positive result for as long as a half or even a full day after the PCR test, it would have great value in identifying pockets of infection that might otherwise be undetected altogether.

    The U.S. government has spent billions of dollars supporting attempts to develop vaccines and therapeutics. “Developing a good vaccine is very difficult to do,” he points out. “It’s a crapshoot that may or may not work. We’re putting billions more into developing therapeutics [treatments for COVID-19] which is really, really difficult.” With rapid testing, by contrast, “We have solutions, sitting in front of us right now, that are cheaper, would be much quicker to build, and much less risky to actually introduce and roll out. And the only thing standing in the way is that there just doesn't seem to be the will to bring a public-health tool to market.”

    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

  • Are At Home COVID 19 Antigen Tests Accurate Enough?

    2:04

    Harvard professor and epidemiologist Dr. Michael Mina responds to the question of accuracy and sensitivity related to inexpensive paper antigen tests. Learn what influences accuracy is why it is relative to the goal of the test (screening for contagious COVID-19 vs testing for low virus levels that are often discovered on the tail end of infection).

    See our previous MedCram videos that have featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus.

    Dr. Mina, Kyle Allred, Dr. Seheult, and MedCram have no financial disclosures related to this topic. We have a keen interest in curbing this pandemic and safely re-opening schools and our economy.

    Michael Mina, MD Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:

    MORE VIDEOS AND RESOURCES ON AT-HOME COVID 19 SCREENING TESTS:

    Dr. Mina is the director (on a volunteer basis) of where you can get more info and streamlined ways to contact your governor and representatives in Congress about at-home COVID 19 screening

    A 3-minute explainer video on inexpensive at-home rapid screening tests by MedCram:

    A video summary and highlights of Dr. Mina's research and ideas in our MedCram COVID 19 Update 98:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    A short explainer video on daily quick tests produced by Dr. Allen:

    Summary Article Featured in the Atlantic about Inexpensive Rapid Testing:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:

    Visit MedCram.com for over 100 coronavirus pandemic updates including sensitivity vs specificity, covid 19 tests, diagnosis and treatment, and many more topics.

    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #rapidtestsnow #dailyquicktest

  • Michael Mina: Covid-19 Testing: Where Science, Policy and Regulation Collide

    1:12:04

    This week's speaker is Michael Mina, an assistant professor of epidemiology and immunology and infectious diseases at the Harvard T.H. Chan School of Public Health.

    Michael Mina is an assistant professor at the Harvard T.H. Chan School of Public Health and a member of the School’s Center for Communicable Disease Dynamics (CCDD). He is also an associate medical director in clinical microbiology (molecular diagnostics) in the Department of Pathology at Brigham and Women’s Hospital, Harvard Medical School. Mina’s research combines mathematical and epidemiological models with high-throughput phage-display based serological laboratory investigations, including development of new technologies and statistical pipelines to better understand the population and immunological consequences and patterns underlying infectious diseases. He earned his MD and PhD from Emory University.

    Organized by Janelia's Sarada Viswanathan and Loren Looger, the Science of COVID-19 seminar series brings in outside experts, covers papers and preprints, and highlights local efforts in testing, production, and analysis.

    LEARN MORE: janelia.org/scienceofcovid19

  • COVID-19: The Year Ahead

    44:27

    What will the next year bring in the coronavirus pandemic? In this Forum Q&A, Harvard Chan epidemiologist Michael Mina and The World’s Elana Gordon looked ahead: Will the anticipation of an imminent vaccine and “coronavirus fatigue” cause people to become lax when it comes to social distancing and masking? Have public health officials and scientists become disillusioned by the public’s response? With cases surging, how will Americans make difficult decisions about holiday travel and celebrations? And why is rapid testing so critical to controlling the course of the pandemic, even before a vaccine is widely available?

    Presented jointly by The Forum at the Harvard T.H. Chan School of Public Health and The World from PRX & WGBH on December 15, 2020.

  • Michael Mina, MD, PhD - The Latest on COVID-19 Testing: How Do We Re-Open?

    42:02

    What are the differences between a molecular test and serological test? Will #COVID-19 tests help us return to the workplace? Michael Mina, MD, PhD is Assistant Professor in Immunology and Infectious Disease, Center for Communicable Disease Dynamics & Department of Epidemiology, at the Harvard T.H. Chan School of Public Health. Dr. Mina is also Associate Medical Director in Clinical Microbiology (molecular diagnostics) in the Department of Pathology at Brigham and Women’s Hospital, Harvard Medical School.

    Our Data Science Zoominars feature interactive conversation with #datascience experts and a Q+A session moderated by Rafael A. Irizarry, PhD, Chair, Department of Data Science at Dana-Farber Cancer Institute.

  • COVID 19 Antigen Testing At Home: Would It Be Too Expensive?

    2:47

    Harvard professor and epidemiologist Michael Mina, MD, PhD, explains the relative cost of frequent, at-home COVID-19 testing (using inexpensive paper strip antigen tests) to allow schools and businesses to re-open.

    Michael Mina, MD Ph.D. is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:

    We have no financial disclosures related to any medical products. MedCram has a strong interest in curbing this pandemic and safely re-opening schools and our economy, and we believe Dr. Mina's approach to testing could be effective - especially compared to the current testing approach in the United States.

    Other Q/A videos with Dr. Michael Mina on inexpensive quick paper antigen tests for COVID-19:

    Paper Strip Tests for COVID-19: Should We Wait Until They Rival PCR Tests?

    Are Antigen Paper Tests for COVID 19 Accurate Enough?

    False Positives and COVID 19 Rapid Tests:

    What if Some Don't Cooperate with COVID 19 Rapid Testing (Herd Immunity and Effects)?


    MORE VIDEOS AND RESOURCES ON AT-HOME COVID 19 SCREENING TESTS:

    Dr. Michael Mina is the director (on a volunteer basis) of where you can get more info and streamlined ways to contact your governor and representatives in Congress about at-home COVID 19 screening

    See our previous MedCram videos that have featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus.

    A 3-minute explainer video on inexpensive at-home rapid screening tests by MedCram:

    A video summary and highlights of Dr. Mina's research and ideas in our MedCram COVID 19 Update 98:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    A short explainer video on daily quick tests produced by Dr. Allen:

    Summary Article Featured in the Atlantic about Inexpensive Rapid Testing:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:

    Visit MedCram.com for over 100 coronavirus pandemic updates including sensitivity vs specificity, covid 19 tests, diagnosis and treatment, and many more topics.

    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #rapidtestsnow #dailyquicktest

  • The Coronavirus Pandemic: Testing, Vaccines, and the Way Forward

    42:56

    The COVID-19 vaccine rollout is now underway. But it will be some time before the vaccine is available to all who want it, and as people wait in line, the virus continues to spread and mutate, “pandemic fatigue” intensifies, and many schools and businesses remain shuttered. In this Forum Q&A, Harvard Chan epidemiologist Michael Mina talked with Reuters Health and Science Correspondent Julie Steenhuysen about the role of rapid testing at this critical moment in the progression of the pandemic. How do rapid tests work, and how could they be deployed at large scale to stop the spread of the virus, with or without widespread vaccination?
     
    Presented jointly by The Forum at the Harvard T.H. Chan School of Public Health and Reuters on February 16, 2021.

  • Dr Michael Mina - Reopen Confidently with Rapid At-Home Testing

    39:18

    Are we pivoting fast enough to address the evolving nature of the pandemic? Widescale affordable and frequent rapid at-home testing can end the pandemic and aid in preventing future pandemics.

    DataRobot's Sally Embrey and Dr. Michael Mina have a candid discussion about the path forward after such a challenging year. Michael has been ringing the bell since early 2020 that we need a 21st-century approach to battle the COVID-19 Pandemic.

  • Michael Mina: When will full testing be in place so society can reopen?

    2:05

    Harvard Chan epidemiologist Michael Mina talks with The World's Jonathan Dyer about the testing infrastructure needed to assist in a safer reopening in the U.S.

    Watch the full conversation here:

  • Michael Mina: Can rapid testing help schools reopen?

    1:33

    Harvard T.H. Chan School of Public Health epidemiologist Michael Mina talks about rapid testing as a tool to help keep schools open and safe.

  • The Coronavirus Pandemic: Advances in Testing, Fighting the Surge

    39:18

    Early in the pandemic’s spread in the U.S., the lack of adequate testing became a major obstacle. That obstacle persists in many places. Social distancing and other measures have bought time. However, some states are experiencing record case numbers, even while others are seeing declines. In this Facebook Live Q&A epidemiologist Michael Mina described hopes for affordable, daily, home testing to help contain virus spread and safely reopen society. He also provided an update on the pandemic, including what can be done about surges of cases in parts of the country. The World’s Elana Gordon moderated.

    Presented jointly by The Forum at the Harvard T.H. Chan School of Public Health and The World from PRX & WGBH on July 14, 2020.

  • Coronavirus Update 98: Rapid COVID 19 Antigen Testing at Home - A Possible Breakthrough

    17:06

    Professor Roger Seheult, MD discusses the current COVID-19 testing strategy in the United States that the CDC estimates picks up less than 10% of infections. Dr. Seheult of MedCram.com features snippets from a recent This Week in Virology (Episode 640) with Dr. Michael Mina of Harvard who explains that the technology exists for at home, inexpensive, self-administered, paper COVID-19 antigen tests that are likely accurate enough to pick up the vast majority of infectious cases of COVID-19. And how lower sensitivity of inexpensive tests may be ideal for a screening test that is performed with high frequency. Utilization of these daily quick tests may provide the optimal path forward to curtail the growth of COVID-19 and open schools and our economy in a much safer way. (This video was recorded July 20, 2020).

    LINKS / REFERENCES:

    See a MedCram Q/A follow up to this video with Dr. Michael Mina:
    Dr. Mina speaks more about COVID-19 testing responds to questions from the comment section below.

    This Week in Virology Episode 640 |

    NEJM |

    NYU Study on Abbott ID Now |

    New York Times |

    Test Sensitivity is Secondary to Frequency (Dr. Mina) |

    Abbott ID Now |

    CNN Test Costs |

    Johns Hopkins Tracker |

    Live Science |

    Korean CDC |

    Washington Post |

    Reuters |

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    PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Pandemic Update 97: Vitamin D & COVID-19 Immunity, The Endothelium, & Deficiencies
    - Coronavirus Pandemic Update 96: RNA Vaccine; Ivermectin; von Willebrand Factor and COVID-19
    - Coronavirus Pandemic Update 95: Widespread Clotting on Autopsy; New COVID-19 Prognostic Data
    - Coronavirus Pandemic Update 94: Inhaled Steroids COVID-19 Treatment; New Pneumonia in Kazakhstan?
    - Coronavirus Pandemic Update 93: Antibodies, Immunity, & Prevalence of COVID-19 - New Data from Spain
    - Coronavirus Pandemic Update 92: Blood Clots & COVID-19 - New Research & Potential Role of NAC
    - Coronavirus Pandemic Update 91: Remdesivir Pricing & Disparities in Drug Availability
    - Coronavirus Pandemic Update 90: Assess The Quality of COVID-19 Info With A Validated Research Tool
    - Coronavirus Pandemic Update 89: COVID 19 Infections Rising in Many States; Dexamethasone Cautions

    All coronavirus updates are at MedCram.com (including the prevention, treatment, vaccine developments, rapid COVID-19 testing, Daily quick tests, coronavirus antigen tests, coronavirus misinformation, and more). We offer many other medical topics at our website.


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    #RapidTestsNow #COVID19 #DailyQuickTest

  • Michael Mina: Should schools open in the fall?

    1:59

    Harvard Chan epidemiologist Michael Mina discusses balancing concerns about virus spread in schools with potential negative public health consequences of long-term closure for both children and adults.

    Watch the full conversation here:

  • September 4, 2019 Seminar Series: Michael Mina

    33:02

    Visit our degree page to learn more about enrollment and degrees available at Harvard Chan School of Public Health


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  • Michael Mina: Advances in virology, immunology, and computation to monitor and control outbreaks

    1:21

    Advances in biological and computational sciences have enabled massive leaps in basic research and medicine over the recent decades. Relative to these medical advances, advances in public health and particularly infectious diseases have been modest. The SARS-CoV2 pandemic has shown us the consequences of investing so fully in medicine without a strong foundation of public health. This talk will provide examples of the technological leaps that are taking place in the medical sciences, in part as a result of COVID-19, and will discuss how they can be coupled with advances in computational tools to usher in exciting new approaches to public health that can help us get out of the SARS-CoV-2 pandemic and prevent similar global catastrophes in the future.

    Michael Mina, MD, PhD, is an assistant professor of epidemiology at the Harvard T.H. Chan School of Public Health and a core member of the School’s Center for Communicable Disease Dynamics (CCDD). He is additionally an assistant professor in immunology and infectious diseases at the Harvard Chan School and associate medical director in clinical microbiology (molecular diagnostics) in the Department of Pathology at Brigham and Women’s Hospital, Harvard Medical School.

    He earned his MD and PhD degrees from Emory University, with doctoral work split between CDC, St. Jude Children’s Research Hospital, the Respiratory and Meningeal Pathogens Research Unit in Johannesburg, South Africa, and the Emory Vaccine Center. He completed his postdoctoral work at Princeton University in ecology and evolutionary biology (of infectious disease dynamics) with Prof. Bryan Grenfell and at Harvard Medical School in the Department of Genetics with Prof. Stephen Elledge. He completed his residency training in clinical pathology at Brigham and Women’s Hospital/Harvard Medical School.

    Mina’s research combines mathematical and epidemiological models with high-throughput phage-display based serological laboratory investigations, including development of new technologies and statistical pipelines to better understand the population and immunological consequences and patterns underlying infectious diseases. Much of the work toward new technology development is performed in close collaboration with Steve Elledge at HMS. Major themes of his lab include (i) development of new approaches (laboratory and statistical methods) to enable extremely high-throughput serological surveillance of infectious pathogens; (ii) use of high-complexity antibody profiling and epidemiological data to understand the pathogenesis of vaccine-preventable diseases, with a specific focus on measles infections and vaccines; (iii) elucidating broad unintended/heterologous effects of vaccines to alter transmission patterns of unrelated infectious pathogens—using serology and dynamical models; and (iv) understanding the life-history of infectious pathogens across ages, genders, geographies, and times. In addition to his interests in infectious diseases, Mina’s research also explores more fundamental questions of immunity and immune repertoires: how they form, how they persist, how they are passed on, and how they become perturbed during natural life-events.

  • Self Testing for Coronavirus at Home with Rapid Antigen COVID 19 Tests

    2:13

    Harvard professor and epidemiologist Michael Mina, MD, Ph.D has been a strong advocate for inexpensive paper strip COVID-19 antigen tests (that provide rapid results in 15 minutes) that he believes are sensitive and accurate enough to turn positive for the vast majority of contagious COVID-19 infections.

    In this video, Dr. Mina challenges the notion that individuals need medical professionals to administer COVID-19 tests and directly give information about results. And how in the past, home pregnancy tests were considered too risky for women to utilize.

    Dr. Mina is an Assistant Professor of Epidemiology, Immunology, and Infectious Diseases at Harvard T. H. Chan School of Public Health. Dr. Mina is also a core member of the Center for Communicable Disease Dynamics (CCDD) and an Associate Medical Director in Clinical Microbiology. Dr. Mina's bio is here:

    We have no financial disclosures related to any medical products. MedCram has a strong interest in curbing this pandemic and safely re-opening schools and our economy, and we believe Dr. Mina's approach to testing could be effective - especially compared to the current testing approach in the United States.

    OTHER Q/A VIDEOS WITH DR. MICHAEL MINA:

    Paper Strip Tests for COVID-19: Should We Wait Until They Rival PCR Tests?

    Are Antigen Paper Tests for COVID 19 Accurate Enough?

    False Positives and COVID 19 Rapid Tests:

    What if Some Don't Cooperate with COVID 19 Rapid Testing (Herd Immunity and Effects)?

    Would Widespread COVID 19 Antigen Testing At Home Be Too Expensive?


    MORE VIDEOS AND RESOURCES ON AT-HOME COVID 19 SCREENING TESTS:

    Dr. Michael Mina is the director (on a volunteer basis) of where you can get more info and streamlined ways to contact your governor and representatives in Congress about at-home COVID 19 screening

    See our previous MedCram videos that have featured Dr. Mina's research about COVID 19 testing and how quickly identifying individuals who are contagious (and who have high levels of SARS-CoV-2 virus) should be the primary focus.

    A 3-minute explainer video on inexpensive at-home rapid screening tests by MedCram:

    A video summary and highlights of Dr. Mina's research and ideas in our MedCram COVID 19 Update 98:

    A 5 minute summary with Dr. Mina of some key differences between COVID-19 antigen tests with rapid results:

    A short explainer video on daily quick tests produced by Dr. Allen:

    Summary Article Featured in the Atlantic about Inexpensive Rapid Testing:

    Dr. Mina's research paper: Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance (Pre-print)

    TWiV 640: Test often, fast turnaround, interview with Michael Mina:

    Visit MedCram.com for over 100 coronavirus pandemic updates including sensitivity vs specificity, COVID 19 tests, diagnosis and treatment, and many more topics.

    ------------------------------------------------------
    Video produced by Kyle Allred, Co-Founder of
    Contact Kyle or MedCram by emailing: customers@medcram.com

    #COVID19 #rapidtestsnow #dailyquicktest

  • Harvard doctor explains how at-home coronavirus tests work

    2:05

    Dr. Michael Mina, a professor of epidemiology at Harvard's School of Public Health, said testing has been one of the major problems during the pandemic and that a new testing strategy could alter the trajectory of the Covid-19 outbreak. Subscribe to CNBC PRO for access to investor and analyst insights:

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    The News with Shepard Smith is CNBC’s daily news podcast providing deep, non-partisan coverage and perspective on the day’s most important stories. Available to listen by 8:30pm ET / 5:30pm PT daily beginning September 30:

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  • TWiV 640: Test often, fast turnaround, with Michael Mina

    1:46:05

    Michael Mina joins TWiV to reveal why frequent and rapid SARS-CoV-2 testing is more important than accuracy, how a daily $1 rapid test could control the pandemic, and why group testing works.

    Show notes are at

  • Lecture 8: “Epidemiology”

    55:50

    The eighth lecture in the COVID-19, SARS-CoV-2 and the Pandemic Series, presented by the MIT Department of Biology. Michael Mina of the Harvard T. H. Chan School of Public Health gave a talk titled “Epidemiology.” For more information on the class, visit

    Date: 10/27/2020

    Help us make more classes like this free to the public:

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    Watch more videos from MIT Bio:

    The department is home to approximately 180 undergraduates, 200 graduate students, 200 postdoctoral researchers, and more than 60 world-renowned faculty, including:
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    We promote a highly collaborative environment that allows for a free exchange of ideas across research areas and academic disciplines. The result is a rigorous, creative, dynamic culture in which scientists and students tackle the important problems and questions in biology and related fields. Our location — at the heart of one of the world’s most important biotech/pharma hubs — creates exciting opportunities for research, employment, and the commercialization of new discoveries.

    For information on captioning and accessibility at MIT, visit

  • Harvard Epidemiologist Describes COVID At-Home Test.

    50

    Harvard University Assistant Professor of epidemiology Dr. Michael Mina says 10 to 20 million rapid at-home tests per day 'would be enough to stop the outbreaks across the United States.

  • Antigen Tests with Accurate and Rapid Results: A Home Test for Coronavirus may Curb Pandemic

    2:27

    A home test for coronavirus (SARS-CoV-2) has been advocated by a variety of infectious disease experts including Harvard epidemiologist Professor Michael Mina, MD.

    This draft video was accidentally posted. Please watch the updated/final version here:

  • The Next Great Frontier | COVID Vaccine Development

    53:14

    The Next Great Frontier: COVID Vaccine Development will explore the challenges and the possibilities of vaccine development, such as the unprecedented speed at which COVID vaccine development is advancing; the expected challenges such as efficacy, public hesitancy, and access; and an introduction of Human Immunomics Initiative (HII). After a brief welcome and opening remarks, expert panelists will discuss health equity and vaccine development, the role of the immune system in vaccine development, the race to develop a vaccine, and vaccine hesitancy. All Harvard Chan alumni are invited and encouraged to tune in.

    Featured Panelists
    Jaap Goudsmit, MD, PhD
    Adjunct Professor of Epidemiology and Infectious Diseases
    Senior Vice President and CSO, Human Vaccine Project

    Albert Hofman, MD, PhD
    Stephen B. Kay Family Professor of Public Health and Clinical Epidemiology
    Chair, Department of Epidemiology

    Michael Mina, MD, PhD
    Assistant Professor in Immunology and Infectious Disease at Harvard T. H. Chan School of Public Health and a core member of the Center for Communicable Disease Dynamics (CCDD). He is also the Associate Medical Director in Clinical Microbiology (molecular diagnostics) in the Department of Pathology at Brigham and Women’s Hospital, Harvard Medical School

    Julia Wu, SD '13
    Research Scientist, Department of Epidemiology

    Moderated by Dr. Sri Sastry, MPH '90
    Ophthalmologist, Bethesda Retina, LLC
    Chair, Harvard Chan Board of Dean’s Advisors

  • Michael Mina | SARS-CoV-2 Inexpensive Rapid Testing

    1:55:12

    Michael Mina | SARS-CoV-2 Inexpensive Rapid Testing
    livestream


    ..
    Po prednáške bude online prenos pokračovať diskusiou. Účasť na nej zatiaľ prisľúbili: Igor Matovič, Veronika Remišová, zástupcovia kancelárie prezidentky SR Libor Melioris a Norbert Kurila, a zástupcovia vedcov a odborníkov Silvia Pastoreková, Martin Šuster, Pavol Čekan, Andrej Belák, Ivan Mikloš, Matej Mišík a Róbert Mistrík.
    ------------------




    Faculty of Mathematics, Physics, and Informatics
    Comenius University, Bratislava

  • Applying the Lessons of the Pandemic to Public Health | More Intelligent Tomorrow #033

    19:31

    In this episode of More Intelligent Tomorrow Podcast together with Dr. Michael Mina we talk about what the world needs to mitigate the spread of a virus is not expensive medical diagnostic testing; it’s public health testing, and there are multiple types of public health testing.

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  • Rapid Testing for COVID-19: Does it Have a Role in COVID Control?

    1:18:31

    The Harvard-Oxford Program in Epidemiology (HOPE) was established to host an annual symposium a year between the Harvard Chan School Department of Epidemiology and Oxford University Nuffield Department of Population Health. Richard Peto was the first keynote speaker in 2018 in a symposium on dementia at HSPH, and Walter Willett was in Oxford in 2019 as the keynote in a symposium on nutritional epidemiology. A symposium planned for the Fall of 2020 turned into the talk that Rory Collins gave on Clinical Trials as part of the epidemiology department seminar series. This is the first of two mini symposia planned for Spring 2021. The next one will likely be in May and hosted by Oxford.
    ------
    ???????????????????? ???????????????????????????? ???????????? ????????????????????-????????: ???????????????? ???????? ???????????????? ???? ???????????????? ???????? ???????????????????? ?????????????????????????????

    0:00:00​ ???????????????????????????? ???????????? ????????????????????????????????????????????????

    Albert Hofman, MD, PhD
    ???????????????????????????? ????. ???????????? ???????????????????????? ???????????????????????????????????? ???????? ???????????????????????? ???????????????????????? ???????????? ???????????????????????????????? ???????????????????????????????????????????????? ????????????????????, ???????????????????????????????????????? ???????? ????????????????????????????????????????????????, ???????????????????????????? ????.????. ???????????????? ???????????????????????? ???????? ???????????????????????? ????????????????????????

    0:02:14 ​????????????????????-???????? ????????????????????????????: ???????????????????? ????????????????????????????, ???????????????????????? ???????????? ???????????????????????????????????????? ????????????????????????????

    Michael Mina, MD, PhD
    ???????????????????????????????????? ???????????????????????????????????? ???????? ???????????????????????????????????????????????? ???????????????????????????????????????? ???????? ????????????????????????????????????????????????, ???????????????????????????? ????.????. ???????????????? ???????????????????????? ???????? ???????????????????????? ????????????????????????

    31:30 ????????????????????????????????????????

    David Hunter, MBBS, ScD
    ???????????????????????????? ???????????????? ???????????????????????????????????? ???????? ???????????????????????????????????????????????? ???????????? ???????????????????????????????? ???????????????????????????????? ???????????????????????????????????????? ???????? ???????????????????????????????????????? ????????????????????????, ???????????????????????????????????????? ???????? ????????????????????????; ???????????????????????????? ????. ???????????????????????????? ???????????????????????????????????? ???????? ???????????????????????? ????????????????????????????????????????, ???????????????????????????????? ???????????????????????????? ????.????. ???????????????? ???????????????????????? ???????? ???????????????????????? ????????????????????????

    42:40 ???????????? ???????????????????????????? ???????????????? ???????????????????? ???????? ???????????????? ???????? ???????????????????????????????? ????????????-???????????????????????????????????????? ?????????????????????????????????????????????

    Tim Peto, PhD
    ???????????????????????????????????? ???????? ???????????????????????????????? ????????-???????????????????????? ???????????? ???????????? ???????????????????????????????????? ???????????????????? ???????? ???????????? ???????????????????????? ???????????????????????????????????????? ???????????????????????????????? ???????????????????????? ???????????????????????????????? ???????????????????????????????????????? ???????? ????????????????????????????????, ???????????????????????????????????????? ???????? ????????????????????????

    1:10:25 ????????????????????????????????????????

    Marc Lipsitch, D.Phil
    ???????????????????????????????????? ???????? ???????????????????????????????????????????????? ???????????????????????????????????????? ???????? ????????????????????????????????????????????????, ???????????????????????????? ????.????. ???????????????? ???????????????????????? ???????? ???????????????????????? ????????????????????????

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    Visit our degree page to learn more about enrollment and degrees available at Harvard Chan School of Public Health


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  • Michael Mina: Rapid Testing, Viruses, and the Engineering Mindset | Lex Fridman Podcast #146

    2:14:11

    Michael Mina is an immunologist, epidemiologist, and physician at Harvard. Please support this podcast by checking out our sponsors:
    - Brave:
    - Athletic Greens: and use code LEX to get 1 month of fish oil
    - ExpressVPN: and use code LexPod to get 3 months free
    - Cash App: and use code LexPodcast to get $10

    EPISODE LINKS:
    Michael's Twitter:
    Michael's Time article:
    Rapid Tests:

    PODCAST INFO:
    Podcast website:
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    Spotify:
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    Full episodes playlist:
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    OUTLINE:
    0:00 - Introduction
    2:32 - Interacting between viruses and bacteria
    6:45 - Deadlier viruses
    10:17 - Will COVID-19 mutate?
    11:51 - Rapid testing
    29:15 - PCR vs rapid antigen tests
    38:59 - Medical industrial complex
    42:51 - Lex takes COVID test
    49:35 - FDA and cheap tests
    52:21 - Explanation of Elon Musk's positive COVID tests
    59:29 - Role of testing during vaccine deployment
    1:02:58 - Public health policy
    1:12:38 - A weather system for viruses
    1:29:30 - Can a virus kill all humans?
    1:35:09 - Engineering a deadly virus
    1:39:51 - AlphaFold 2 and viruses
    1:45:46 - Advice for young people
    1:53:54 - Time as a buddhist monk
    1:59:58 - Meditation
    2:07:36 - Meaning of life

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  • Testing our way out of COVID 19: A bumpy but possible path forward

    1:28:00

    Michael Mina, Harvard T. H. Chan School of Public Health

    Michael Mina has been advocating for widespread frequent testing even with lower sensitivity than with the FDA approved PCR test. In a recent preprint with Dan Larremore ( it was shown that daily testing, even with 100 fold lower sensitivity, can dramatically reduce the spread of COVID-19. The claim is that such tests, if used correctly, can stop the pandemic and open the economy at the same time.There is an effort underway to convince the FDA to allow for such tests to be used in non-clinical scenarios. (see

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  • HarvardX: Confronting COVID-19 - Class 6: Diagnosis and Testing

    1:1:57

    OVERVIEW​: The technical ability to test for and diagnose an epidemic disease has historically been a crucial aspect of both public health and medical approaches. This has clearly been the case with COVID-19. This class will explore the science and technology of testing for COVID-19, as well as the problems and possibilities that testing offers for mitigating the epidemic. We will also learn about the accuracy of alternative tests and difficulties in making tests accessible. GUEST FACULTY​:
    ● Margaret Bourdeaux​ - Research Director, Security and Global Health Project, Harvard Belfer Center, Harvard Kennedy School; Associate Physician, Brigham and Women’s Hospital
    ● Michael Mina​ - Assistant Professor of Epidemiology, Harvard T. H. Chan School of Public Health, core member of the Center for Communicable Disease Dynamics (CCDD); Assistant Professor in Immunology and Infectious Diseases at HSPH, and Associate
    10
    Medical Director in Clinical Microbiology (molecular diagnostics) in the Department of
    Pathology at Brigham and Women’s Hospital, Harvard Medical School
    ● Pardis Sabeti​ - Professor at the Center for Systems Biology and Department of
    Organismic and Evolutionary Biology, Harvard University and the Department of Immunology and Infectious Disease, Harvard School of Public Health and Broad Institute Member

  • The Coronavirus Pandemic: Antibody Testing and Reopening Society

    34:40

    In this Facebook Live Q&A, Harvard Chan epidemiologist Michael Mina reviewed antibody testing in the U.S., and updated our viewers on other testing and contact tracing measures that will ultimately allow us to reopen society. The World’s Jonathan Dyer moderated.
     
    Presented jointly by The Forum at the Harvard T.H. Chan School of Public Health and The World from PRX & WGBH on May 15, 2020.

  • Can we test ourselves out of the COVID-19 pandemic?

    2:1:15

    A symposium to explore the opportunities and challenges of mass testing as an exit strategy for the COVID-19 pandemic.

    Date: Thursday, 4th March 2021
    Time: 16:00 - 18:00 (GMT)

    Programme

    16:00 – 16:15
    Introduction – Professor Irene Petersen, UCL & Anushka Asthana, The Guardian

    16:15 – 16:30
    Mass testing as an exit strategy for the COVID-19 pandemic – Associate Professor Michael Mina, Harvard University

    16:30 – 16:45
    A new tool in the toolbox – evaluation of lateral flow tests - Professor Tim Peto, University of Oxford

    16:45 – 17:00
    Integrating lateral flow tests in civic COVID-19 responses – experiences from Liverpool – Professor Iain Buchan, Liverpool University

    17:00 – 17:15
    Mitigating Risk among Asymptomatic Individuals Newly Diagnosed with Covid-19 - Eric Kutscher, New York University School of Medicine

    17:15 - 17:30
    The Role of Mass Testing In Reopening the Society - Ryan Wain – Advisor at Tony Blair Institute for Global Change

    17:30 – 17:55
    Debate led by Anushka Asthana

    17:55 – 18:00
    Summary - Irene Petersen

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