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Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)

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  • Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained

    14:12

    Professor Roger Seheult, MD discusses the AstraZeneca and Oxford DNA COVID-19 Vaccine: How it works, and what we know about the safety, efficacy, and side effects at this time.

    Dr. Seheult illustrates the differences and similarities between the AstraZeneca / Oxford vaccine candidate and those from Moderna and Pfizer / BioNTech.

    The complete data from each of these SARS CoV 2 vaccine trials have not been released nor peer-reviewed at this time, and none of the COVID 19 vaccines have received FDA authorization to date.

    Dr. Sheult explains some of the potential advantages of the AstraZeneca Oxford vaccine candidate including a lower cost and that it only requires regular refrigeration. (This video was recorded on November 24, 2020).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    AstraZeneca press release |

    AstraZeneca-Oxford Covid-19 Vaccine Up to 90% Effective in Late-Stage Trials (Wall Street Journal) |

    Why the AstraZeneca-Oxford Covid-19 vaccine is different (Vox) |

    Why the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism (Vox) |

    AstraZeneca Registered Trial in US |

    Pfizer claims its Covid-19 vaccine is 90 percent effective so far. Here’s what we actually know. (Vox) |

    These Covid-19 vaccine candidates could change the way we make vaccines — if they work (Vox) |

    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


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    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?

    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, mRNA vaccine, COVID 19 prevention, Pfizer vaccine and Moderna vaccines, Biontech, AstraZeneca Oxford coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • x
  • AstraZeneca Second Doses vs Moderna and Pfizer COVID Vaccines

    8:04

    Roger Seheult, MD of MedCram discusses new AstraZeneca coronavirus vaccine data and compares second doses of the Oxford AZ vaccine with Pfizer and Modera vaccines. View all Dr. Seheult's videos at:

    (This video is MedCram COVID-19 update 136 and was recorded on November 9, 2021)

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    AstraZeneca’s COVID-19 vaccine: benefits and risks in context (European Medicines Agency) |

    Effectiveness of heterologous ChAdOx1 nCoV-19 and mRNA prime-boost vaccination against symptomatic Covid-19 infection in Sweden: A nationwide cohort study (ScienceDirect) |

    Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna) (MedCram) |

    All coronavirus updates are at MedCram.com (including more discussion on astrazeneca vaccine second dose, the COVID delta variant, moderna, pfizer booster, vaccine rollout, blood clots, AstraZeneca second doses, moderna vaccine, and more).


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    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #SARSCoV2 #Coronavirus

  • x
  • Coronavirus Update 127: Delta Variant and Vaccines

    18:09

    Professor Roger Seheult, MD of MedCram with an update on the effectiveness of four major vaccines against the delta variant of COVID-19: Pfizer / BioNTech, Moderna, AstraZeneca, and Johnson and Johnson Vaccine (This video was recorded on July 19, 2021).

    See the video Dr. Seheult references: 10 Tips if you Get COVID-19 here:

    Please see our most recent video on Previous Infection vs. The Delta Variant:


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 General overview of SARS-CoV-2 variants
    02:44 Characteristics of the SARS-CoV-2 delta variant (B.1.617.2)
    03:21 Preliminary data on delta variant infection rates by age & risk of severe infection
    05:14 How delta variant is affecting COVID-19 case numbers in the UK, Israel, and United States
    06:55 How do the COVID-19 vaccines stack up against delta variant? Effectiveness of Pfizer-BioNTech vaccine
    12:20 Data on the effectiveness of Moderna vaccine against the delta variant
    12:42 Data on effectiveness of Oxford-AstraZeneca vaccine against the delta variant
    13:41 Information on Johnson & Johnson vaccine effectiveness against related SARS-CoV-2 variants (no current data on delta variant)
    15:29 Vaccination rates across the United States
    17:04 What to do if you’re infected with COVID-19?


    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    5 Things To Know About the Delta Variant (Yale Medicine) |

    REACT-1 round 12 report: resurgence of SARS-CoV-2 infections in England associated with increased frequency of the Delta variant (Imperial College) |

    SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness (The Lancet) |

    Vaccines highly effective against B.1.617.2 variant after 2 doses (GOV.UK) |

    Effectiveness of COVID-19 vaccines against hospital admission with the Delta (B.1.617.2) variant (Public Health England) |

    Moderna Provides a Clinical Update on the Neutralizing Activity of its COVID-19 Vaccine on Emerging Variants Including the Delta Variant First Identified in India (Moderna) |

    How much protection COVID-19 vaccines give you against the Delta variant, according to the best available data (Business Insider) |

    The total number and mass of SARS-CoV-2 virions (NIH) |

    Covid vaccine: How many people in the UK have been vaccinated so far? (BBC News) |

    All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #SARSCoV2 #Coronavirus

  • Coronavirus Update 119: Pfizer BioNTech COVID Vaccine

    14:13

    Professor Roger Seheult, MD discusses details from the CDC that answer many COVID 19 vaccine related questions: Who will be the first to receive the COVID-19 vaccine in the United States? What if you've already had a COVID-19 infection? What type of side effects (or reactogenicity) are being reported? Can pregnant women or immunocompromised people get the vaccine? Is it ok to stop wearing a mask after I receive the vaccine? (This video was recorded on December 14, 2020).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    Use of Pfizer-BioNTech COVID-19 Vaccine: Clinical Considerations (CDC) |

    Find Your Place in the Vaccine Line (New York Times) |

    ACIP Evidence to Recommendations for Use of Pfizer-BioNTech COVID-19 Vaccine under an Emergency Use Authorization (CDC) |

    COVID-19 ACIP Vaccine Recommendations (CDC) |

    CDC greenlights advisory group’s decision to recommend Pfizer vaccine for use (Washington Post) |

    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)
    - Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?

    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, mRNA vaccine, COVID 19 prevention, Pfizer vaccine and Moderna vaccines, Biontech, AstraZeneca Oxford coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • x
  • Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna

    11:49

    Professor Roger Seheult, MD explains the Johnson and Johnson / Janssen Pharmaceuticals vaccine candidate for COVID 19. Dr. Seheult illustrates how the Johnson & Johnson adenovirus vaccine works, the efficacy/safety (based on preliminary data), and how the vaccine compares to the Moderna vaccine and the Pfizer BioNTech vaccine. (This video was recorded on February 4, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    Interviewer: Kyle Allred, Physician Assistant, Producer / Co-Founder of MedCram.com

    LINKS / REFERENCES:

    A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants (NIH) |

    Johnson & Johnson Announces Single-Shot Janssen COVID-19 Vaccine Candidate Met Primary Endpoints in Interim Analysis of its Phase 3 ENSEMBLE Trial (Johnson & Johnson) |

    J&J one-dose Covid vaccine is 66% effective, a weapon but not a knockout punch (STAT) |

    One-shot COVID-19 vaccine is effective against severe disease (ScienceNews) |

    UK COVID Symptom Study |

    Doctor Explains The PREVENTION & TREATMENT For The Coronavirus | Roger Seheult & Lewis Howes (Lewis Howes YouTube Channel) |


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 120: Anticoagulants (Blood Thinners) Improve Hospital Outcomes (Full Dose)
    - Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (Clinical Considerations)
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)
    - Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?

    All coronavirus updates are at ad-free MedCram.com (including this video on the Johnson and Johnson Vaccine).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavirus

  • Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine

    14:41

    Professor Roger Seheult, MD discusses the Moderna COVID-19 mRNA vaccine: How it works and what we know about the safety, efficacy, and side effects at this time.

    No mRNA vaccine has ever been approved by the FDA, but Moderna and Pfizer/BioNTech hope to receive emergency approval based on preliminary data from their ongoing vaccine trials.

    Moderna's two-dose vaccine regimen does not require special refrigeration (the Pfizer vaccine is supposed to be stored at -70 Celcius) but a variety of questions remain:
    Will the vaccine prevent transmission and asymptomatic spread?
    How long will immunity last?
    Will “94.5% effective” hold up to peer-review and additional data when it is gathered?

    (This video was recorded on November 17, 2020).

    Dr. Seheult is the co-founder and lead instructor at


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    Outcomes for Out-of-Hospital Cardiac Arrest in the United States During the Coronavirus Disease 2019 Pandemic (JAMA Cardiology) |

    Moderna’s Covid-19 vaccine is strongly effective, early look at data show (STAT) |

    mRNA Platform: Enabling Drug Discovery & Development (Moderna) |

    What is mRNA? (Moderna) |

    Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study (Moderna) |


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?
    - Coronavirus Pandemic Update 105: FDA Authorized Treatments; COVID 19 Vaccine Update
    - Coronavirus Pandemic Update 103: Convalescent Plasma Treatment & the FDA; College Campuses Close

    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, mRNA vaccine, COVID 19 prevention, Pfizer and Moderna vaccines, Biontech, coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Roger Seheult, MD
    Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
    Associate Professor at the University of California, Riverside School of Medicine

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • x
  • COVID-19 Vaccines: MODERNA | PFIZER/BIONTECH | ASTRAZENECA

    43:41

    Official Ninja Nerd Website:
    Ninja Nerds!

    During this lecture Professor Zach Murphy will be discussing COVID-19 vaccines including Moderna, Pfizer/BioNTech, and Astrazeneca/Oxford.

    We are NOT sponsored and/or endorsed by Moderna, Pfizer/BioNTech, or Astrazeneca. We are presenting on RESEARCH and in no way is any of the information provided our own view or opinions.

    This will be a lecture packed with the process vaccine developers must go through; which includes a preclinical phase and phases I-III. Including information about OPERATION WARP SPEED and how this has expedited the normally lengthy vaccine process.

    We will then discuss how Moderna, Pfizer/BioNTech, and Astrazeneca vaccines work in the human body, preventing the SARS-CoV-2 virus and hopefully, ending this global pandemic.

    Finally-- Zach presents on all of the most current data that each of the vaccine companies have released outlining the vaccine procedure and how it will be administered, the vaccine efficacy (as a percentage), optimal storage temperature of the vaccine in order to remain viable, and the number of vaccine units these companies are capable of producing. We hope you enjoy this lecture and be sure to support us below!

    IMPORTANT INFO (MUST READ):
    One thing to emphasize that wasn’t harped on enough from this lecture is when these vaccines lead to an immunogenic reaction as we described above, which leads to formation of Memory B cells and Memory T cells. This is important because if we are exposed to the virus those memory cells are now primed and able to recognize and mount a powerful immune response against the virus.

    LASTLY, one additional point and clarification is when those cytotoxic T cells produce destructive molecules that damage host cells it’s important to realize that those are memory cytotoxic T cells primed by the Vaccine that damage host cells that ARE INFECTED with the SARS-COV-2 virus, NOT CELLS processing the vaccine.

    Big Takeaway:
    1. Vaccine stimulates antibody production to protect against virus IF INFECTED.
    2. Vaccine stimulates development of memory T and B cells to protect against virus IF INFECTED.

    References |
    Regulatory Affairs Professionals Society (RAPS) COVID-19 Tracker


    Outline:
    00:00 - Intro and Overview
    01:00 - Vaccine Development Phases Overview
    05:08 - Pre-Clinical Phase
    06:32 - Phase I
    08:29 - Phase II
    12:36 - How the Vaccines Work (Moderna and Pfizer/BionTech)
    21:16 - How the Vaccines Work (AstraZeneca/Oxford)
    25:33 - Vaccine Data (Moderna)
    30:30 - Vaccine Data (Pfizer/BionTech)
    35:21 - Vaccine Data (AstraZeneca)
    43:02 - Wrap-Up

    Join this channel to get access to perks:


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  • Coronavirus Update 125: Variants, Vaccine Uptake, Sinovac, Brazil, India, Israel

    15:01

    Professor Roger Seheult, MD of discusses the dramatic rise in COVID 19 in Brazil and India, Global Vaccine Update, The Sinovac CoronaVac Vaccine, and new research on coronavirus vaccine efficacy vs. variants in Israel, South Africa, and other locations. (This video was recorded on April 12, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Updates on COVID-19 daily new cases and daily deaths around the world
    00:30 Brazil and India emerge as global “hotspots” for COVID-19
    03:09 International vaccination campaign tracker
    04:05 Mechanism of Sinovac’s COVID-19 vaccine developed in China
    06:42 Efficacy of Sinovac vaccine on different SARS-CoV-2 variants
    08:01 COVID-19 vaccination and infection rates in Chile
    08:50 Three countries to watch carefully: Brazil, India, and Chile
    09:27 Israel among highest in the world for COVID-19 vaccine coverage
    09:48 Is Pfizer vaccine becoming less effective against South African variant in Israel?
    12:39 Serious COVID-19 cases in Israel fall below 300 for first time since December
    13:13 Could low vaccination rate be responsible for high COVID-19 death rate in Brazil?
    14:15 What to do if COVID-19 cases are surging near you


    LINKS / REFERENCES:

    Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna (MedCram) |

    If You Get COVID 19: Optimize Immune System (MedCram) |

    Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (MedCram) |

    Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (MedCram) |

    Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (MedCram) |

    Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (MedCram) |

    More Than 781 Million Shots Given: Covid-19 Tracker (Bloomberg) |

    How the Sinovac Vaccine Works (NYT) |

    Sinovac: Brazil results show Chinese vaccine 50.4% effective (BBC News) |

    Israeli data shows South African variant able to ‘break through’ Pfizer vaccine (The Times of Israel) |

    Pfizer Covid Vaccine Protects Against South African Variant, ‘Highly Effective’ Against Disease For Six Months, Updated Trial Data Shows (Forbes) |

    Pfizer and BioNTech Confirm High Efficacy and No Serious Safety Concerns... (Pfizer) |

    India bans remdesivir exports as COVID-19 cases surge (Aljazeera) |

    Chile Covid-19 vaccination drive adds to Sinovac efficacy data (S. China Morning Post) |

    Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals (medRxiv) |

    Covid-19: Why have deaths soared in Brazil? (BBC News) |

    All coronavirus updates are at MedCram.com (including more discussion on COVID variants, Sinovac, CoronaVac, COVID mutations, California variant, coronavirus variant, vaccine uptake, and more).


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavirus

  • Delta Variant Versus Previous COVID 19 Infection vs. Vaccines

    16:18

    Roger Seheult, MD of MedCram explains how natural immunity (from a previous COVID-19 infection) compares with vaccines (Pfizer, Moderna, AstraZeneca) VS. the Delta coronavirus variant. (This video was recorded on July 24, 2021).

    Correction: Strasbourg is in France (near the German border), not in Germany.

    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Is natural immunity from previous COVID-19 infection strong enough against Delta variant?
    00:32 Research study of 50,000+ patients from the Cleveland Clinic
    03:07 Qatar airport study shows previous infection with SARS-CoV gives reasonable immunity against reinfection
    05:46 UK data suggests low risk of COVID-19 reinfection among population
    07:04 Study on antibody response effectiveness (from vaccines and natural infection) at neutralizing several COVID-19 variants, including Delta
    13:33 Monoclonal antibodies shown to have little effectiveness against Delta variant
    14:31 Patients urged to get both doses of Pfizer or Moderna, especially for protection against Delta variant
    14:59 MedCram resources for medical providers treating COVID-19 patients and the case for lung ultrasounds

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    See the video Dr. Seheult references about Lung Ultrasound in COVID 19:

    LINKS / REFERENCES:

    Can You Get Delta Variant if You Already Had COVID-19? (Healthline) |

    Necessity of COVID-19 vaccination in previously infected individuals (medRxiv) |

    Associations of Vaccination and of Prior Infection With Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar (JAMA) |

    New national surveillance of possible COVID-19 reinfection, published by PHE (GOV.UK) |

    Study highlights need for full Covid vaccination to protect against Delta variant (STAT) |

    All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


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    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #Deltavariant #Coronavirus

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  • Coronavirus Update 123: COVID 19 Vaccines vs. Variants

    10:42

    How well will COVID-19 vaccines work against the coronavirus variants first discovered in the UK, South Africa, and Brazil? Dr. Seheult discusses the research we have so far on SARS CoV 2 mutations. (This video was recorded on February 23, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    COVID: UK variant spreading rapidly in Germany (DW) |

    Germany: Schools reopen for younger children amid rising COVID infections (DW) |

    Where schools are reopening in the US (CNN) |

    Adapted booster vaccines in the works (Medical News Today) |

    Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera (Science) |

    Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera (Cell) |

    mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants (bioRxiv) |

    Moderna COVID-19 Vaccine Retains Neutralizing Activity Against Emerging Variants First Identified in the U.K. and the Republic of South Africa (Moderna) |


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    Please visit MedCram.com for the full series:
    - Coronavirus Update 122: The Research So Far on COVID-19 and Vaccines vs. Pregnancy
    - Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna
    - Coronavirus Update 120: Anticoagulants (Blood Thinners) Improve Hospital Outcomes (Full Dose)
    - Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (Clinical Considerations)
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna mRNA vaccines)

    All coronavirus updates are at MedCram.com (including more discussion on COVID variants, COVID mutations, and more).

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


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    #COVID19 #SARSCoV2

  • Which COVID Vaccine Booster is Best? Pfizer vs. Moderna vs. J. Johnson

    16:01

    Roger Seheult, MD of MedCram explains COVID 19 booster data on Moderna, Pfizer-BioNTech, and Johnson & Johnson and the efficacy of each coronavirus booster vs. full vaccination.

    (This video was recorded on October 27, 2021)


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Which COVID-19 booster should I take?
    00:15 Pre-print study looking at outcomes for original vaccines and randomized booster combinations in the United States
    01:53 Side effects for various boosters given to patients with either J&J, Moderna, Pfizer original vaccines
    05:46 Preliminary booster efficacy data: how well do IgG bind to SARS-CoV-2 spike proteins?
    10:29 Preliminary data from Pfizer-BioNTech: Efficacy of a booster on top of fully vaccinated people in randomized, placebo-controlled trial


    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    Pfizer And BioNTech Announce Phase 3 Trial Data Showing High Efficacy Of A Booster Dose Of Their COVID-19 Vaccine (Pfizer) |

    Heterologous SARS-CoV-2 Booster Vaccinations - Preliminary Report (medRxiv) |

    All coronavirus updates are at MedCram.com (including more discussion on the COVID delta variant, vaccine passport, and more).


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    #COVID19 #SARSCoV2 #Coronavirus

  • Top 8 Vaccines for Covid-19 | Comparison

    3:29

    In this video we have discussed about the Vaccines globally present for the Covid-19.
    These 8 vaccines shows the efficacy of 60-90 % depending upon the variant we are targeting. The top 8 vaccines that we have currently present includes the :
    Pfizer BioNtech
    Moderna
    Johnson and Johnson
    Astrazeneca /Covisheild
    Sputnik V
    Novavax
    Covaxin
    Sinovac/Coronavac

  • RNA Vaccines - Basis of Pfizer and Moderna COVID-19 vaccines, Animation

    3:19

    The basis of upcoming Pfizer and Moderna coronavirus vaccines. How it works? Pluses and minuses. For comparison of different vaccines, as well as events of immune response, role of different immune cells (T-cells, B-cells, APC), see this video:
    This video is available for instant download licensing here:
    ©Alila Medical Media. All rights reserved.
    Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
    All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
    Vaccines prepare the immune system, getting it ready to fight disease-causing organisms, called pathogens. A vaccine is introduced to the body to mimic infection, triggering the body to produce antibodies against the pathogen, but without causing the illness. Conventional vaccines usually contain a weakened or inactivated pathogen; or a piece of a protein produced by the pathogen, called an antigen.
    RNA vaccines are a new generation of vaccines. Instead of the antigen itself, RNA vaccines contain a messenger RNA – mRNA - that encodes for the antigen. Once inside the body’s cells, the mRNA is translated into protein, the antigen, by the same process the cells use to make their own proteins. The antigen is then displayed on the cell surface where it is recognized by the immune system. From here, the sequence of events is similar to that of a conventional vaccine.
    Some RNA vaccines also contain additional mRNA coding for an enzyme, which, after being translated in host cells, can generate multiple copies of the antigen-encoding mRNA. This essentially amplifies the production of antigen from a small amount of vaccine, making the vaccine more effective. These are called self-amplifying RNA vaccines.
    RNA vaccines are easier and safer to produce than conventional vaccines. This is because mRNA molecules can be synthesized in a cell-free system using a DNA template with a sequence of the pathogen; while conventional vaccines usually require a more complicated and risk-prone process of growing large amounts of infectious pathogens in chicken eggs or other mammalian cells. Without the risks of being contaminated by infectious elements or allergens from egg cultures, RNA vaccines are also safer for patients.
    Because protein synthesis occurs in the cytoplasm, RNA molecules do not need to enter the nucleus, so the possibility of them integrating into the host cell genome is low. RNA strands are usually degraded by cellular enzymes once the protein is made.
    The relative simplicity of the production process makes it easier to standardize and scale, enabling rapid responses to emerging pandemics. Other advantages include lower production costs, and the ease of tweaking RNA sequences to adapt to rapidly-mutating pathogens.
    On the minus side, it can be challenging to deliver mRNA effectively to the cells, since RNA sequences and secondary structures may be recognized and destroyed by the innate immune system as soon as they are administered intravenously. These limitations can be overcome by optimizing codons, using modified nucleosides to avoid recognition, and packaging RNA into protective nanoparticles.
    Another disadvantage is that most RNA vaccines require uninterrupted refrigeration for transportation and storage, which can be a hurdle for vaccine distribution. Research is ongoing to engineer thermostable vaccines.

  • Mixing Vaccine Boosters For COVID 19

    4:46

    Roger Seheult, MD of MedCram explains the FDA recommendations for COVID 19 vaccine boosters.

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    (This video was recorded on October 21, 2021)

    LINKS / REFERENCES:

    Coronavirus (COVID-19) Update: FDA Takes Additional Actions on the Use of a Booster Dose for COVID-19 Vaccines (FDA) |


    All coronavirus updates are at MedCram.com (including more discussion on the COVID delta variant, vaccine passport, COVID news, and more).


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    #COVID19 #SARSCoV2 #Coronavirus

  • AstraZeneca COVID-19 Vaccine EXPLAINED vs Pfizer vs Moderna vs Johnson & Johnson Coronavirus Vaccine

    4:49

    AstraZeneca COVID-19 Vaccine EXPLAINED vs Pfizer vs Moderna vs Johnson & Johnson Coronavirus Vaccine. Doctor Wagner, a real life emergency physician is back to discuss the latest on COVID-19, vaccine progress, Oxford/AstraZeneca covid 19 vaccine, how it works, the safety, effectiveness, side effects, reactions, trial, cases, and other covid news you need to know.

    Renewed concerns that the trajectory of COVID-19 cases in the U.S. is moving in the wrong direction. However, covid vaccine distribution is going strong. In the US, the first two available Covid-19 vaccines were mRNA vaccines from Pfizer/BioNTech and Moderna. Both vaccines have very high efficacy rates, of around 95%, even with the emergence of new COVID strains and the South African variants. But the third vaccine introduced in the US, from Johnson & Johnson, using virus-based technology, has a considerably lower efficacy rate: just 66%. Now a fourth coronavirus vaccine from Oxford/AstraZeneca has come forward. The AZD1222 vaccine against COVID-19 has an efficacy of 63.09% against symptomatic SARS-CoV-2 infection. However, some countries in the European Union have temporarily suspended use of the AstraZeneca COVID-19 vaccine as a precautionary measure based on reports of rare blood coagulation disorders (blood clots) in persons who had received the vaccine. Other countries in the EU – having considered the same information - have decided to continue using the vaccine in their immunization programmes. Now, Is AstraZeneca vaccine approved in US? Is there a safe vaccine for covid-19? Doctor ER Jordan Wagner will explain all of that in this covid 19 vaccine update news video. Have you received a COVID-19 vaccination yet? Let real doctor Jordan Wagner know in the comments!

    OTHER VIDEOS ABOUT COVID-19 & ASTRAZENECA VACCINE:

    @Doctor Mike Hansen - NEW Drugs for COVID 19 Prevention & Treatment


    @Good Morning America - COVID-19 cases increased even with progress on vaccination l GMA


    @CBS This Morning - U.S. sees uptick in COVID-19 cases despite increased vaccine supply


    @ABC News - COVID-19 cases increase in 21 states | WNT


    @Vox - Why you can't compare Covid-19 vaccines


    @MedCram - Medical Lectures Explained CLEARLY - COVID Variants vs. Coronavirus Vaccines (AstraZeneca, Pfizer, Moderna, Johnson & Johnson) + Immunity


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    #AstraZeneca #COVID19 #Coronavirus

    LINKS & REFERENCES:

    AstraZeneca - Research-Based BioPharmaceutical Company


    AstraZeneca COVID-19 Vaccine (AZD1222) | CDC


    AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis | AstraZeneca


    WHO statement on AstraZeneca COVID-19 vaccine safety signals | WHO


    The Oxford/AstraZeneca COVID-19 vaccine: what you need to know | WHO


    NIAID Statement on AstraZeneca Vaccine | NIH


    Vaxzevria (previously COVID-19 Vaccine AstraZeneca) | European Medicines Agency


    AZD1222 US Phase III primary analysis confirms safety and efficacy | AstraZeneca


    Disclaimer: Video was filmed on March 23, 2021. There may be more up-to-date information after the posting date.

    ** WARNING** If you feel like you are actually experiencing a real-life medical emergency, immediately stop watching and call 9-11 or contact a medical professional. The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace an appointment with your own personal doctor/mental health professional!

  • Coronavirus Update 122: The Research So Far on COVID-19 and Vaccines vs. Pregnancy

    24:53

    Professor Roger Seheult, MD discusses the impacts of COVID 19 on pregnant women, and the research we have so far on COVID vaccine safety in pregnancy. For more on this topic, please see our interview with reproductive immunologist Dr. Victoria Male:

    (This video was recorded on February 14, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    Explainer on COVID19 vaccination, fertility and pregnancy (Dr. Viki Male, Imperial College London) |

    REG 174 INFORMATION FOR UK HEALTHCARE PROFESSIONALS (UK Department of Health and Social Care) |

    Vaccines and Related Biological Products Advisory Committee Meeting December 17, 2020 (FDA) |

    Public Assessment Report Authorisation for Temporary Supply (MHRA) |

    Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection (JAMA) |

    COVID-19 pandemic effect on early pregnancy: are miscarriage rates altered, in asymptomatic women? (Archives of Gynecology and Obstetrics) |

    Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients (AJOG) |

    Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living syst. review and meta-analysis (BMJ) |

    I’m pregnant. Should I get a COVID* vaccine? (UMASS) |

    VACCINES AND RELATED BIOLOGICAL PRODUCTS ADVISORY COMMITTEE BRIEFING DOCUMENT (FDA) |

    Vaccines and Related Biological Products Advisory Committee Meeting December 17, 2020 (FDA) |

    Public Assessment Report Authorisation for Temporary Supply (MHRA) |

    Influenza Vaccine Efficacy and Effectiveness in Pregnant Women: Systematic Review and Meta-analysis (PubMed) |

    VAERS - Vaccine Adverse Event Reporting System |


    THE MEDCRAM WEBSITE:

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    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna
    - Coronavirus Update 120: Anticoagulants (Blood Thinners) Improve Hospital Outcomes (Full Dose)
    - Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (Clinical Considerations)
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna mRNA vaccines)

    All coronavirus updates are at MedCram.com (including more discussion on covid fertility, covid vaccine pregnancy, and more).

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    #COVID19 #SARSCoV2

  • COVID 19 Vaccine Deep Dive: Safety, Immunity, RNA Production,

    34:29

    Professor Shane Crotty, PhD joins MedCram to answer a series of COVID vaccine questions including what are the chances of long-term side effects? How safe is RNA vaccine (i.e. Pfizer / BioNTech and Moderna Vaccines) technology? How long does mRNA from a vaccine stay in our cells? What else goes in vaccines? How long does immunity last? Why are T-Cells so important? Why does Pfizer's vaccine need to stay SO cold?

    Shane Crotty, PhD is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Professor Crotty also has an academic appointment with the University of California San Diego. See his full bio here:
    Professor Crotty on Twitter:

    Interviewer: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com

    See our new interview with Prof. Crotty on how virus mutations (UK variant and S. African variant) may be impacting COVID-19 transmission and vaccine efficacy.

    Research referenced in this video from Prof. Crotty and his team was published Jan. 6, 2021, in the prestigious Journal Science:

    New York Times article highlighting Prof. Shane Crotty's research:

    00:00 Introducing Prof. Shane Crotty's Research
    0:35 How long does COVID-19 immune memory last?
    0:57 The three primary aspects of immune memory: antibodies, killer T cells, and helper T cells
    2:25 The anatomy (protein makeup) of SARS-CoV-2
    3:02 Why is spike protein the primary target?
    5:17 Could a mutation allow SARS-CoV-2 to infect without spike protein?
    7:02 Utilizing lipid nanoparticles to deliver mRNA and the role of RNA normally
    9:52 What human cells does an RNA vaccine go into?
    10:36 How long does mRNA from a vaccine stay in human cells?
    11:44 What else goes in vaccines besides mRNA and lipid nanoparticles? Any preservatives or adjuvants?
    12:30 Why are adjuvants used in many vaccines?
    14:08 Protein production from mRNA
    15:00 Why utilize the extra step of mRNA to code for protein antigens?
    17:28 Are mRNA vaccines the future of vaccine development?
    19:18 Any chance for mRNA to enter our cells' nucleus?
    20:55 The immune response to a coronavirus vaccine
    23:17 Expected symptoms from immune response to a vaccine vs. vaccine side effects
    25:50 Should people who've had COVID-19 get vaccinated?
    27:27 Immunity from COVID vaccine vs. a natural infection
    28:30 Why does the Pfizer vaccine need to be stored so cold?
    29:04 What would you say to a family member who is nervous about a rushed vaccine and RNA technology?
    32:37 What about the possibility of long term side effects from RNA vaccines?
    33:30 What's next for Shane Crotty's research team?

    (This video was recorded on December 16, 2020).

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    PREVIOUS / RECENT MEDCRAM COVID-19 INTERVIEWS:

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing and Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including more videos on the Pfizer vaccine, Moderna vaccines, BioNTech vaccine, vaccine side effects, COVID 19 vaccine mechanism, AstraZeneca Oxford coronavirus vaccine, side effects of COVID 19 vaccine, COVID 19 treatments, and more):

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    #COVID19 #SARSCoV2 #Coronavaccine

  • Why you cant compare Covid-19 vaccines

    7:02

    What a vaccine's efficacy rate actually means.

    Sign up for our newsletter:

    In the US, the first two available Covid-19 vaccines were the ones from Pfizer/BioNTech and Moderna. Both vaccines have very high efficacy rates, of around 95%. But the third vaccine introduced in the US, from Johnson & Johnson, has a considerably lower efficacy rate: just 66%.

    Look at those numbers next to each other, and it's natural to conclude that one of them is considerably worse. Why settle for 66% when you can have 95%? But that isn't the right way to understand a vaccine's efficacy rate, or even to understand what a vaccine does. And public health experts say that if you really want to know which vaccine is the best one, efficacy isn't actually the most important number at all.

    Further reading from Vox:

    Why comparing Covid-19 vaccine efficacy numbers can be misleading:

    The vaccine metric that matters more than efficacy:

    The limits of what vaccine efficacy numbers can tell us:

    Vox.com is a news website that helps you cut through the noise and understand what's really driving the events in the headlines. Check out

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  • COVID-19 mRNA Vaccine: Will It Change My DNA?

    4:01

    This video is brought to you by the SMART Imagebase at a website where subscribers can download thousands of medical images and videos created by Nucleus Medical Media, including this one. The SMART Imagebase website contains over 24,000 items on anatomy, physiology, embryology, surgery, trauma, pathology, diseases, conditions and other topics. Students, educators and professionals use them in lectures, courses, presentations, professional training and more. To request more information on how your school or business can subscribe, please visit

    #mRNAvaccine #COVID19Vaccine #COVID19

    mRNA Vaccines for COVID-19. Vaccines are substances that protect you from harmful diseases. Most vaccines contain parts of weakened or dead germs that trigger your immune system to fight the disease. But mRNA vaccines for COVID-19 are different. They contain a substance, called mRNA, that teaches your cells how to make a protein that triggers an immune response. In order to understand how these vaccines work, it’s important to know what mRNA is and how it normally makes proteins your body needs. Most cells in your body have a “command center” inside them, called the nucleus. It contains genetic material, called DNA, that consists of instructions for building and maintaining your body. Proteins are one of the building blocks of your body. When a new body protein needs to be built, instructions for building it are copied from your cell’s DNA and converted into a “message,” called messenger RNA, or mRNA. Then, the mRNA travels out of the nucleus to a protein-building machine in your cell, called a ribosome. As the ribosome “reads” the “message” from the mRNA, it builds the protein your body needs. mRNA vaccines take advantage of this process to help give you immunity to COVID-19. Each vaccine contains special mRNA that provides instructions for your cells to build a harmless piece of the virus, called the spike protein. The spike protein is found on the surface of the SARS-CoV-2 coronavirus that causes COVID-19. Each piece of the mRNA from the vaccine is wrapped in a protective coating. The vaccine is given as a shot in the upper arm. In the body, the mRNA particles enter your cells. Once inside the cell, the mRNA travels to a ribosome. Using the mRNA from the vaccine, the ribosome makes only a piece of the spike protein from the virus. After making the piece of the spike protein, your cell destroys the mRNA from the vaccine. It’s important to know that the mRNA from the vaccine never enters the cell’s nucleus or changes its DNA in any way. Next, your cell presents the piece of the spike protein on its surface. This allows your immune cells to detect the protein and recognize that it doesn’t belong there. As a result, your immune cells begin making antibodies as part of an immune response to the virus. In the future, if you catch the virus, the antibodies recognize and attach to the spike protein pieces on infected cells and the spike proteins on the virus. This marks them for immediate destruction by other immune cells. Like all vaccines, the benefit of these mRNA vaccines is that they give vaccinated people protection from the virus without having to get sick with COVID-19. Most mRNA vaccines for COVID-19 require you to get a second shot within a few weeks. Sometime after getting the vaccine, you may have symptoms, such as a fever. This is normal. It means the vaccine is working to make you immune to the virus. Vaccines protect you, your family, and your community from diseases that can be dangerous, or even deadly. For up to date information about vaccines for COVID-19 visit the Centers for Disease Control and Prevention website at CDC.gov.

    ANH21248

  • Whats the difference between the major Covid-19 vaccines?

    9:50

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    Covid-19 plagued the world for most of 2020, but at the end of the year, vaccines developed and approved at record speed started to become available for use. With the largest vaccination drive in history under way, what are the differences between the Covid-19 vaccines? How effective are they? What are the potential side effects of some of the vaccines, what are the dosage requirements and how will they get to you? Here’s what you need to know about the Covid-19 vaccine front-runners.


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  • Moderna vs Pfizer: Which COVID-19 vaccine is better? | ABC News

    4:48

    Moderna’s COVID-19 vaccine is the third to be approved by Therapeutic Goods Administration (TGA) in Australia.

    As an mRNA vaccine, it’s remarkably similar to Pfizer’s version.

    But they have some key differences.

    Jeremy Fernandez explains how each vaccine works.

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    ABC News In-depth takes you deeper on the big stories, with long-form journalism from Four Corners, Foreign Correspondent, Australian Story, Planet America and more, and explainers from ABC News Video Lab.

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  • COVID-19: What is the difference between the Pfizer vaccine and Moderna vaccine?

    1:20

    Both the Pfizer-BioNTech vaccine and Moderna vaccine are mRNA vaccines.
    For more detailed information about each vaccine, visit cdc.gov/coronavirus

  • 2 doses of Pfizer-BioNTech vaccine plus Moderna booster jab has ‘slight edge’

    1:38

    A study by the Ministry of Health (MOH) on Covid-19 booster shots has found that two doses of the Pfizer-BioNTech vaccine followed by a Moderna booster shot has a “slight edge” in terms of reducing risk of infection, over three doses of Pfizer-BioNTech. Health Minister Ong Ye Kung shared this during a press conference by the national Covid-19 task force on Monday (Nov 15).

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  • Dr Norman Swan looks at the latest advice on the AstraZeneca COVID-19 vaccine | 7.30

    6:32

    The expert advisory group on immunisation is now urging younger people to talk to their doctor about getting the AstraZeneca vaccine if they live in an outbreak zone. It’s also updated its advice on early second doses of the vaccine.

    Dr Norman Swan takes a look.

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  • All Types of COVID-19 Vaccines, How They Work, Animation.

    5:56

    How it works. mRNA vaccine (Pfizer, Moderna), DNA & Viral vector vaccines (Johnson & Johnson (J&J, JNJ), Oxford-AstraZeneca, Inovio, Sputnik V); protein/peptide vaccine (Novavax, EpiVacCorona), conventional inactivated (CoronaVac of Sinovac, Covaxin, Sinopharm). Mechanism of each type of coronavirus vaccines explained. Vaccine-induced immune response as compared to natural immunity.
    This video is available for instant download licensing here:
    ©Alila Medical Media. All rights reserved.
    Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
    During a natural viral infection, infected cells alert the immune system by displaying pieces of viral proteins on their surface. They are said to present the viral antigen to immune cells - cytotoxic T-cells, and activate them.
    Debris of dead cells and viral particles are picked up by professional antigen-presenting cells, (dendritic cells...). Dendritic cells patrol body tissues, sampling their environment for intruders. After capturing the antigen, dendritic cells leave the tissue for the nearest lymph node, where they present the antigen to another group of immune cells - helper T-cells. Viral particles also activate B-cells.
    These cells mount 2 types of immunity specific to the viral antigen: cell-mediated immunity and antibody-mediated immunity.
    Vaccines deliver viral antigens to trigger immune responses without causing the disease. The events of a vaccine-induced immune response are similar to that induced by a natural infection, although some types of vaccines may induce only antibody-mediated immunity (B cell immunity, not T cell (cellular) immunity).
    Many existing vaccines contain a weakened or an inactivated virus. Because the whole virus is used, these vaccines require extensive safety testing. Live attenuated vaccines may still cause disease in people with compromised immune systems. Inactivated vaccines (Sinovac/China, Covaxin/India) only induce humoral (B cell) immunity.
    Subunit vaccines contain only part of the virus, usually a spike protein (peptide - EpiVacCorona/Russia). These vaccines may not be seen as a threat to the immune system, and therefore may not elicit the desired immune response. For this reason, certain substances, called adjuvants, are usually added to stimulate the antigen-presenting cells to pick up the vaccine.
    Nucleic acid vaccines contain genetic information for making the viral antigen, instead of the antigen itself. Naked DNA vaccines (Inovio, phase 2/3 clinical trials) require a special delivery method to reach the cell’s nucleus (electroporation). Alternatively, a harmless, unrelated virus may be used as a vehicle to deliver the DNA. In this case, the vaccine is also known as viral-vector vaccine (Sputnik V/Russia, Oxford-AstraZeneca, Johnson & Johnson's). For example, the Oxford-AstraZeneca Covid-19 vaccine uses a chimpanzee adenovirus as a vector. The adenoviral genome is modified to remove viral genes, and the coronavirus spike gene is added. This way, the viral vector cannot replicate or cause disease, but it acts as a vehicle to deliver the DNA. Why a non-human adenovirus is used?
    Do DNA vaccines change human DNA?
    mRNA vaccines (Pfizer, Moderna) are delivered within a lipid covering that will fuse with the cell membrane. The mRNA is translated into viral antigen, which is then displayed on the cell surface. mRNA vaccines are extremely unlikely to integrate into human genome.
    All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.

  • Does the AstraZeneca COVID vaccine cause blood clots? | DW News

    4:37

    Vaccinations with the Astra Zeneca coronavirus vaccine are being halted in Denmark, Norway and Iceland - for now. We asked an expert about how serious the concerns about the vaccine should be taken, and on how likely it is to be the cause of reported blood clots. Is not getting the jab more dangerous than waiting?

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  • EMA: Pfizer, Moderna vaccines effective against COVID-19 variants | COVID-19 Vaccines | Latest News

    5:20

    The EU’S drug agency has approved the storage of the Pfizer-BioNTech coronavirus vaccine in fridges for up to a month. The European Medicines Agency said this could improve the flexibility in countries’ vaccine rollout.

    #EMA #COVID19Vaccines #WorldNews

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  • Canada Recommends Mixing, Matching Of COVID-19 Vaccines- AstraZeneca, Pfizer, Moderna

    2:00

    #COVIDVaccine #VaccineMixing #Coronavirus #COVID19 #RepublicTV

    Based on the study from UK and Spain, Canada, on Tuesday recommended mixing and matching second doses of COVID-19 vaccines. The country is using AstraZeneca, Pfizer, and Moderna and has suggested citizens to combine jabs interchangeably in certain situations. The National Advisory Committee on Immunization (NACI) has extended its support to the decision and updated its guidance to provinces and territories on mixing and matching.

    Canada's Chief Public Health Officer Dr. Theresa Tam also gave a green signal to the process while adding that this is nothing new.

    This is not a new concept, so having a multi-dose series in terms of vaccines given by manufacturers is something that public health has used over time for many other vaccines. When vaccines programs and supplies change this is not an unusual thing to do, said Dr. Theresa Tam to CBC News.

    Dr. Theresa Tam further cited the example of mixing shots for influenza and Hepatitis proving this phenomenon is not new.

    The NACI guidance comes from research conducted in UK, Spain that said mixing and matching shots are safe and effective. The study further recommended first shot of the AstraZeneca vaccine can be followed by either Moderna or Pfizer. Following the recommendations, Canadians have also been advised to take either of the two shots as a second dose after taking first dose of Moderna or Pfizer.

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  • mRNA Vaccines - Layman’s version , plus some FAQs, Animation.

    4:48

    The basis of upcoming Pfizer and Moderna coronavirus RNA vaccines. How it works? Plus some FAQs: Does mRNA vaccine change my DNA? Why do people want me to take the vaccine?
    For comparison of different vaccines, as well as events of immune response, role of different immune cells (T-cells, B-cells, APC), see this video:
    This video is available for instant download licensing here:
    ©Alila Medical Media. All rights reserved.
    Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
    All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
    The purpose of a vaccine is to mimic an infection, activating the body’s immune response, but without causing the illness. Conventional vaccines usually contain a weakened or inactivated virus; or a piece of a viral protein, called an antigen. These viral elements do not cause disease, but they trick the immune system into thinking that an infection has occurred so that it responds by producing antibodies against the virus. RNA vaccines are a new generation of vaccines. Instead of a protein antigen, they contain mRNA, meaning messenger RNA. As its name suggests, mRNA is basically a messenger, carrying genetic message from DNA to protein. In order to function, a human cell needs to constantly produce proteins based on genetic information in its DNA. Because DNA is located in the nucleus of the cell, and protein synthesis occurs in the cytoplasm, an intermediate molecule is required to transmit the information. mRNA copies the information from DNA and brings it to the cytoplasm, where it is translated into protein. mRNA consists of 4 basic building blocks called A, U, C and G. The information it carries is the sequence of these letters. RNA vaccines contain mRNA strands that have the information for making the viral antigen, usually a viral spike protein. Once inside the body’s cells, the mRNA is translated into protein, the antigen, by the same process the cells use to make their own proteins. The antigen is then displayed on the cell surface where it is recognized by the immune system. From here, the sequence of events is similar to that of a conventional vaccine. RNA vaccines are easier and safer to produce than conventional vaccines. Conventional vaccines typically require growing large amounts of infectious viruses, usually in chicken eggs, and then inactivating them. Vaccines produced this way are at risks of being contaminated with LIVE viruses and allergens from egg culture. Such risks do NOT exist with RNA vaccines because mRNA molecules can be synthesized in a CELL-FREE system using a DNA template that contains information for making the viral protein. The mRNA is made from the same building blocks as natural mRNA, so it has the same chemical composition as natural mRNA. The relative simplicity of the production process makes it easier to standardize and scale, enabling rapid responses to emerging pandemics. In case the virus MUTATES, it’s also simple to change the mRNA sequence to match the mutation. Will RNA vaccines change my DNA? RNA vaccines do NOT change your DNA. This is because in order to do so, the mRNA must convert into DNA, enter the nucleus, and integrate into the cell’s DNA. This is a complex multiple-step process requiring action of several enzymes that the cell does NOT have. Instead, the cell has plenty of enzymes that can readily destroy the mRNA, so the mRNA is usually degraded after the protein is made. Why do people try so hard to convince others to take vaccine? The answer is herd immunity. When enough people in a community are vaccinated, the whole community, including the individuals that were not vaccinated, is protected against the disease. This phenomenon is known as herd immunity. Herd immunity is possible because a pathogen cannot spread without a sufficient number of vulnerable hosts. An analogy is the spread of wildfires. A wildfire only spreads where there is vegetation, or fuel, for it to burn; it would stop at a river, or a large open space. These are called firebreaks. Vaccinated individuals essentially serve as firebreaks, preventing spread of infections caused by pathogens. Herd immunity is important because not everyone can be vaccinated. Often, the very young, very old, and immunocompromised people must rely on vaccinated individuals to stop disease outbreaks. To note, however, that the number of vaccinated individuals must be great enough for community protection to occur, just like a firebreak must be large enough to stop a fire.

  • Singapore’s 3 COVID-19 Vaccines – And Is One Better Than The Others?

    3:40

    Singapore has ordered the Pfizer-BioNTech, Moderna and Sinovac vaccines as the first three of its portfolio in the fight against the coronavirus pandemic.

    ALSO WATCH: Is the vaccine safe? Your questions answered

    Both the Pfizer-BioNTech (also in use in Britain and the US) and Moderna (used in the US) vaccines use messenger RNA (mRNA) technology that involves injecting snippets of the COVID-19 genetic code, triggering an immune response without actually exposing the patient to the virus. Both vaccines are said to have an efficacy rate of about 95%.

    The China-made Sinovac vaccine uses an inactivated COVID-19 virus to trigger an immune response. There is a lack of specific results on its efficacy at the moment. As of January 7, 2020, the Sinovac vaccine has not been used in any country.

    Co-chair of the COVID-19 multi-ministry task force Lawrence Wong tells #TalkingPoint why the Singapore Government convened an expert panel as early as April 2020 to look into early purchases of COVID-19 vaccines based on early-stage clinical information.

    Director of communicable diseases at the Ministry of Health (MOH) Vernon Lee said “all the vaccines approved in Singapore are safe and efficacious”, but that some may be more suited to certain subpopulations. The Pfizer vaccine for instance - the only one in use in Singapore as of Jan 8 - is not for use in those with severe allergic reactions.

    ALSO WATCH:
    The Search For A COVID-19 Vaccine:
    Inside Coronavirus Human Vaccine Trials In Singapore:
    Is A Safe COVID-19 Vaccine By 2021 Really Possible?:


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  • Covid-19 vaccines: Moderna vs. Pfizer vs. Johnson & Johnson comparison

    8:24

    We asked Dr. Stephen Thomas, chief of Infectious Diseases at SUNY Upstate Medical University, what we need to know about the vaccines right now and what we could learn in the coming months.

    Watch the video for a deeper explanation about the three vaccines currently available in the U.S. — Moderna, Pfizer/BioNTech and Johnson & Johnson. Moderna and Pfizer are messenger RNA, or mRNA vaccines and Johnson & Johnson is a viral vector vaccine. All three are designed to protect against Covid-19.

    According to the CDC, rather than inject the body with a weakened version of the coronavirus, these vaccines teach the body to make a protein which triggers an immune response. It’s those antibodies that our bodies produce that help keep us safe when confronted with the actual virus.

    Side Effects
    The mRNA vaccines have been administered to over 80 million people in the United States and they are safe and effective, Thomas said. Thomas was the lead principal investigator for the worldwide Pfizer/BioNTech vaccine trial.

    In data from the trials, Thomas noted, “The safety profile of these vaccines are all pretty similar, most people will experience some kind of pain at the site the vaccine was injected and most people say the pain is mild to moderate.

    Dr. Thomas also mentioned these other common side effects:
    • Mild to moderate headache
    • Mild to moderate fatigue
    • 30 to 40 percent of people might have muscle aches or joint pain
    • About ten to fifteen percent of people might develop a fever

    “The good news is if it’s going to happen to you, because it doesn’t happen to everyone, it happens pretty soon after you get vaccinated and once it starts it goes away within a couple of days,” Thomas said.

    “With Pfizer and Moderna rolling out over 80 million doses of vaccine the side effects continue to be the same as the data from the trials and we aren’t seeing any new side effects or more severe side effects,” he added.

    What about the variants?
    Work is being done in laboratories with the Moderna and Pfizer vaccines, testing people’s antibodies to see if the antibodies will neutralize the variants.

    Thomas said, “They are not as good at neutralizing those variants as they are against the predominant strain in the United States which is from China. But experiments are continuing and there is some concerning data there, which is why it’s important that we vaccinate as many people as possible, because it’s a race against the variants.”

    Thomas noted that the vaccines are still working at fifty to sixty-percent efficacy against the new variants.

    “Just to put it in context, the annual flu vaccine is about forty-five percent efficacious,” he said.

    How important is the two-dose vaccine time schedule?
    Thomas said it’s important to get these vaccines as close to the schedule as possible as they were tested in the trials. If a change is unavoidable, Thomas recommends delaying the second dose rather than getting it ahead of schedule.

    What is herd immunity and when will we have it?
    Herd immunity is achieved when enough of the population has become immune to a disease (generally through vaccinations) that it makes it difficult for that disease to spread.

    That would mean even those who are not immune would be protected.

    “Right now, about fifteen percent of the country has received at least one dose of vaccine, but that’s a far cry from the 70 to 80-percent that we are going to need to achieve herd immunity,” Thomas said.

    Thomas doesn’t think it’s going to be a vaccine supply issue, but more of a willingness for people to be vaccinated. “We’re vaccinating 2 million people a day, if that were to go to 3 million, and we have 320 million people in the country, we could achieve herd immunity by late summer.”

  • MOA of Messenger RNA-Based COVID-19 Vaccines

    1:54

    This animation demonstrates the mechanism of action of Messenger RNA based vaccines for COVID-19 (SARs-CoV-2) from companies such as Pfizer-BioNTech, Moderna, and Arcturus Therapeutics.

  • The COVID-19 Vaccines from Johnson & Johnson and AstraZeneca: Whats in Them and How Do They Work?

    11:20

    Learn about the composition and delivery mechanism for the new classes of COVID-19 vaccines based on adenovirus from Johnson & Johnson and AstraZeneca with Dr. Jonathan Genzen, COO of ARUP Laboratories and an Associate Professor at the University of Utah School of Medicine.

  • Heres the key differences between Moderna and Pfizer vaccines: Leading vaccine researcher

    3:35

    Padmini Pillai, an immunoengineer at MIT, discusses the main issues with both the Moderna and Pfizer-BioNTech COVID vaccines, including why one must be stored at much colder temperatures than the other. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

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  • mRNA vaccines, explained

    6:48

    Why some Covid-19 vaccines were developed faster than any vaccine ever.

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    Researchers working on Covid-19 vaccines have smashed speed records, bringing new vaccines from development to distribution in less than a year. They did this with the help of billions of dollars of unprecedented global investment -- but also, in some cases, with a new type of vaccine technology.

    There are four traditional types of vaccines, and they all require the growing and handling of live pathogens in a lab, a time-consuming process than can add months or years to development. But two new types of vaccines skip that step altogether by moving that work from the lab to our bodies. mRNA vaccines, like the ones from Pfizer-BioNTech and Moderna; and Adenovirus vaccines, like those from Johnson & Johnson and AstraZeneca; do this by sending genetic instructions directly into our cells, which then produce the harmless protein the body needs to learn to fight Covid-19. Because these proteins are produced from within cells rather than injected from the outside, they may be less likely to provoke adverse reactions in the recipient.

    The result has been a host of vaccines developed faster than ever. But it's also ushered us into a new age of vaccine technology, one in which we can send our own bodies the instructions on how to protect themselves. That technology is already being used to drive research on vaccines for HIV and cancer. These new types of vaccines are weapons we developed to fight the coronavirus - but their real impact is just beginning.

    Note: The headline on this video has been changed.
    Previous title: How the newest vaccines fight Covid-19

    Further reading:
    Our original article on Vox.com by Umair Irfan:

    A breakdown of the types of vaccines:

    Infographic on the differences between mRNA vaccines and traditional vaccines:

    The New York Times has a really wonderful in-depth breakdown of how each of the vaccines work:

    Vox.com is a news website that helps you cut through the noise and understand what's really driving the events in the headlines. Check out

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  • ASL Video Series: Different COVID-19 Vaccines

    13:01

    COVID-19 vaccines are safe and effective at reducing your risk of severe illness from COVID-19.  CDC does not recommend one vaccine over another. In general, you should get the first COVID-19 vaccine that is available to you.

    More COVID-19 information in ASL:

    More COVID-19 information in English text:

    Development of these materials was supported by a grant from the CDC Foundation, using funding provided by its donors. The materials were created in partnership with the Center for Inclusive Design and Innovation at Georgia Tech. 

    This video can also be viewed at

  • Fact check: Heres why COVID vaccinations do not change your DNA ???? ????| DW News

    5:10

    With so many myths about COVID-19 vaccines regarding their impact on our health, many people don’t know what to believe. In our fact check, find out what you need to know about the mRNA vaccines — as we expose the myths and reveal the facts.

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    #mRNA #Vaccine #FactCheck

  • Oxford-AstraZeneca Covid vaccine has a distinct comparative advantage, Lancet editor says

    3:25

    Richard Horton, editor-in-chief of The Lancet, discusses the efficacy of the Oxford-AstraZeneca coronavirus vaccine shortly after a paper published in the medical journal found it to be safe and effective.

  • Coronavirus Vaccine:DNA & mRNA. AstraZeneca, Pfizer and Moderna

    2:57

    This educational video explains the genetic vaccines using DNA & mRNA.

  • EU decides to not renew AstraZeneca Covid-19 vaccine order | Biontech Pfizer | Latest English News

    3:24

    The European Union has seemingly decided not to renew its deal with pharmaceutical giant AstraZeneca for its Covid-19 vaccine according to a leading official.

    #Astrazeneca #EU #COVID19

    About Channel:

    WION -The World is One News, examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to the politics of the world. People are tired of biased reportage and we stand for a globalised united world. So for us the World is truly One.

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  • Oxford-AstraZeneca COVID-19 vaccine found to be between 70% and 90% effective

    4:31

    A COVID-19 vaccine developed by Oxford University and AstraZeneca has been found to be between 70% and 90% effective, depending on the dose. Trial results have shown that perfecting the dosage could further increase protection. Pfizer and Moderna have both reported over 90% protection. Cost and storage is where the Oxford vaccine may have the upper hand. It can be kept at fridge temperature, making it much easier to distribute around the world. In contrast, Pfizer's vaccine needs to be stored at -70°C. AstraZeneca is ready to make three billion doses worldwide in 2021.

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  • South Korea: 2 patient dies after receiving AstraZeneca vaccine | COVID vaccine update |English News

    1:26

    South Korea reported 444 new confirmed COVID-19 cases on Tuesday, up from 344 on Monday, raising the country’s tally to 90,816 infections.

    #SouhKorea #AstraZenecaVaccine #EnglishNews

    About Channel:

    WION -The World is One News, examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to the politics of the world. People are tired of biased reportage and we stand for a globalised united world. So for us the World is truly One.

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  • Oxford/AstraZeneca Covid-19 vaccine can be up to 90% effective

    3:17

    British pharmaceutical giant AstraZeneca on Monday said an interim analysis of clinical trials showed its coronavirus vaccine has an average efficacy of 70% in protecting against the virus. One dosing regimen showed an effectiveness of 90% when trial participants received a half dose, followed by a full dose at least one month apart. The other showed 62% efficacy when given as two full doses at least one month apart. CNBC's Meg Tirrell reports. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    The coronavirus vaccine being developed by AstraZeneca and the University of Oxford was found to be “highly” protective, potentially paving the way for a vaccine that is more affordable and easier to distribute than some of its peers.

    An interim analysis of clinical trials showed the Oxford-AstraZeneca vaccine had an average efficacy of 70% in protecting against the virus.

    Researchers said this figure could be as high as 90% by tweaking the dose, but the overall results show the vaccine’s efficacy is slightly lower than other leading candidates.

    Both Pfizer-BioNTech and Moderna reported preliminary results last week showing that their respective Covid vaccines were around 95% effective.

    However, White House coronavirus advisor Dr. Anthony Fauci has previously said a vaccine that is 50% or 60% effective against the virus would be acceptable.

    It is hoped a Covid vaccine could help to bring an end to the coronavirus pandemic that has claimed more than 1.3 million lives worldwide.

    Huge challenges remain before a vaccine can be rolled out. The global battle to secure prospective supplies has raised concerns about equitable access, while questions remain over the logistics of mass production, distribution, and cost.

    Equity analysts at Jefferies said it was “challenging” to compare the efficacy of AstraZeneca’s vaccine with those of Pfizer-BioNTech and Moderna, citing key differences in how the trials have been conducted.

    The analysts highlighted weekly swabbing to detect Covid-19 among participants involved in AstraZeneca’s trials — not just confirmation of suspected cases by symptoms as in U.S. trials. They also stressed that a meningococcal vaccine was used for comparison, not placebo.

    The Oxford-AstraZeneca vaccine was assessed over two dosing regimens. One showed an effectiveness of 90% when trial participants received a half dose, followed by a full dose at least one month later.

    The other showed 62% efficacy when given as two full doses at least one month apart.

    No hospitalizations or severe cases of the disease were reported in participants receiving the vaccine.

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  • Coronavirus Update: India finds minuscule clot risk from AstraZeneca jab | Latest English News

    3:10

    Major regulators have listed blood clots as a rare side effect of AstraZeneca COVID-19 vaccine. India has found 26 suspected cases of bleeding and clotting among recipients of the AstraZeneca vaccine.

    #AstraZeneca #India #COVID19

    About Channel:

    WION -The World is One News, examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to the politics of the world. People are tired of biased reportage and we stand for a globalised united world. So for us the World is truly One.

    Please keep discussions on this channel clean and respectful and refrain from using racist or sexist slurs as well as personal insults.

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  • COVID-19 Vaccine Safety: What You Need to Know

    5:50

    COVID-19 Vaccine Safety: What You Need to Know (Updated September 2021)
    In this updated video, Denver Health Chief Medical Officer Connie Price, MD and Denver Health Critical and Pulmonary Care Physician Anuj Mehta, MD address the evidence showing why the novel coronavirus (COVID-19) vaccines are safe and effective, including how the vaccines work, potential side effects and answers to commonly asked questions.

    Other topics addressed include: the speed at which the vaccines were developed, why you should get a COVID vaccine, what people with allergies or other medical conditions should consider before getting vaccinated, why the vaccines are effective in communities of color and the differences between the Pfizer, Moderna and Johnson and Johnson (J&J) Vaccines.

    Vaccinations are available to everyone age 12 and over in Colorado. Denver Health will continue to vaccinate patients according to the latest state guidelines. Make an appointment for the vaccine of your choice at Denver Health at

    For complete information about the safety and efficacy of the coronavirus vaccines, visit

    For all the latest updated information and Denver Health's vaccine distribution plans according to Colorado state and federal guidelines, visit

    0:19-0:50 Safety, approval and authorization of COVID-19 vaccines and clinic trials
    0:51-0:59 Cost of coronavirus (COVID-19) vaccines
    1:00-1:42 How the Pfizer and Moderna coronavirus (COVID-19) vaccine works, including explanation of vaccine's effect on mRNA, not DNA
    1:43-1:54 Effectiveness of Pfizer and Moderna coronavirus vaccines
    1:55-2:22 Effectiveness of Johnson and Johnson coronavirus vaccine
    2:28-3:12 Why the coronavirus (COVID-19) vaccines were developed so quickly and how we know the vaccines are safe
    3:13-4:00 Best reasons for communities of color (Black, Hispanic/Latino/Latinx, Indigenous) to get a COVID-19 (coronavirus) vaccine
    4:01-4:36 What are the side effects of the COVID-19 (coronavirus) vaccines?
    4:37-5:02 Should I get a coronavirus (COVID-19) vaccine if I have allergies?
    5:03-5:15 Who should not get a coronavirus (COVID-19) vaccine?
    5:16-5:27 When should you schedule getting a coronavirus (COVID-19) vaccination?
    5:28-5:39 Coronavirus (COVID-19) Vaccine information for pregnant women and breastfeeding mothers

    #COVID-19 #vaccine #coronavirus #DHBlog

  • COVID-19: Doctor explains mixing and matching with AstraZeneca vaccine | Vancouver Sun

    11:27

    B.C.’s regular coronavirus update on June 7, 2021.
    ___

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  • Countries in line for Pfizers COVID-19 vaccine | Coronavirus vaccine update | WION News

    3:03

    The US and Europe are in line to get the first doses of an experimental coronavirus vaccine after a partnership between Pfizer Inc. and BioNTech SE delivered dazzling preliminary results in a large patient trial.


    #Pfizer #CoronavirusVaccine #WION



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    WION -The World is One News, examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to the politics of the world. People are tired of biased reportage and we stand for a globalised united world. So for us the World is truly One.

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  • Covid-19: Oxford-AstraZeneca coronavirus vaccine approved for use in UK ???? @BBC News live - BBC

    8:33

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    Top stories this morning 0:00

    The Oxford-AstraZeneca vaccine has been approved for use in the UK, with the first doses due to be given on Monday.

    The UK has ordered 100 million doses - enough to vaccinate 50 million people.

    Along with the Pfizer-BioNTech jab, the UK now has enough to cover the entire population, Health Secretary Matt Hancock said.

    He described the development as a significant moment in the fight against the virus.

    Speaking on BBC Breakfast, he said he could now say with confidence we can vaccinate everyone.

    We've got enough of this vaccine on order to vaccinate the whole population - 100 million doses. Add that to the 30 million doses of Pfizer and that's enough for two doses for the entire population, he added.

    It comes as millions more people in England are expected to be placed under the toughest tier four - stay at home - coronavirus restrictions amid escalating case numbers.

    On Tuesday, 53,135 new Covid cases were recorded in the UK - the highest single day rise since mass testing began - as well as 414 more deaths within 28 days of a positive test.

    Get the full story ????

    It's Wednesday 30 December 2020. Get the latest news, sport, business and weather from the BBC's Breakfast team live on iPlayer daily from 6am.

    BBC Breakfast | BBC News | BBC

    #BBC #BBCiPlayer #BBCNews #BBCNewsLive #BBCCoronavirus #Coronavirus #Covid-19 #CoronavirusOutbreak #Corona #CoronavirusUK

    All our TV channels and S4C are available to watch live through BBC iPlayer, although some programmes may not be available to stream online due to rights. If you would like to read more on what types of programmes are available to watch live, check the 'Are all programmes that are broadcast available on BBC iPlayer?' FAQ ????

  • Denmark stops use of AstraZeneca Covid-19 vaccine | Europe Coronavirus | Latest English News | WION

    1:59

    Denmark has become first nation in Europe to ban the use of AstraZeneca Covid-19 vaccine. The move is expected to delay the country’s vaccination drive by several weeks.

    #Denmark #AstraZeneca #EuropeCoronavirus

    About Channel:

    WION -The World is One News, examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to the politics of the world. People are tired of biased reportage and we stand for a globalised united world. So for us the World is truly One.

    Please keep discussions on this channel clean and respectful and refrain from using racist or sexist slurs as well as personal insults.

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  • AstraZeneca Vs Pfizer: Which Covid Vaccine Is Better?

    9:09

    The people have been cursing COVID-19 ever since it has started spreading out. But salute to the hardworking scientists that we are now able to protect ourselves from this deadly virus. Yes! The vaccine of COVID-19 has been made and successfully the clinical trials have been completed.
    Recently, there has been a lot of talk about the two vaccines AstraZeneca and Pfizer. Now the question is what they are and are they really reliable?


    ★☆★ Thank you so much for watching our video! Hope you enjoyed it, make sure you like, comment, share and SUBSCRIBE to our channel and click the ???? icon for notifications when we post I new video. If you have any questions or requests feel free to leave them in the comments below.

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    Vaccines are of course our biggest weapon in fighting this COVID-19 war. There is no specific evidence that which vaccine is more effective. Both AstraZeneca and Pfizer vaccines are developed by senior doctors and scientists. Both vaccines have successfully passed the clinical trials. We are working closely with international counterparts in understanding the global safety experience of COVID-19 vaccines and on the rapid sharing of safety data and reports. People should still go and get their COVID-19 vaccine when asked to do so, said Dr. Phil Bryan of the UK’s medicine and health products regulatory agency.

    In this video, we will reveal The Battle Between AstraZeneca and Pfizer.

    0:00 Intro
    0:53 AstraZeneca
    1:29 What is the oxford AstraZeneca vaccine?
    1:39 How oxford AstraZeneca vaccine is made?
    2:31 How does this vaccine works?
    4:06 Is AstraZeneca vaccine safe to use?
    5:11 Who can take AstraZeneca vaccine?
    5:31 Pfizer
    5:49 How Pfizer BioNtech vaccine is made?
    6:29 How Pfizer BioNtech vaccine work?
    7:09 Who should get this vaccine?
    7:28 Is Pfizer vaccine safe to use?
    8:07 Which vaccine should you get?


    Check out more videos from Tech Space:


    #astrazeneca #pfizer #covid19 #vaccine

    ★ Thank you for watching our video: AstraZeneca Vs Pfizer: Which Covid Vaccine Is Better?

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