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Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)

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  • Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained

    14:12

    Professor Roger Seheult, MD discusses the AstraZeneca and Oxford DNA COVID-19 Vaccine: How it works, and what we know about the safety, efficacy, and side effects at this time.

    Dr. Seheult illustrates the differences and similarities between the AstraZeneca / Oxford vaccine candidate and those from Moderna and Pfizer / BioNTech.

    The complete data from each of these SARS CoV 2 vaccine trials have not been released nor peer-reviewed at this time, and none of the COVID 19 vaccines have received FDA authorization to date.

    Dr. Sheult explains some of the potential advantages of the AstraZeneca Oxford vaccine candidate including a lower cost and that it only requires regular refrigeration. (This video was recorded on November 24, 2020).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    AstraZeneca press release |

    AstraZeneca-Oxford Covid-19 Vaccine Up to 90% Effective in Late-Stage Trials (Wall Street Journal) |

    Why the AstraZeneca-Oxford Covid-19 vaccine is different (Vox) |

    Why the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism (Vox) |

    AstraZeneca Registered Trial in US |

    Pfizer claims its Covid-19 vaccine is 90 percent effective so far. Here’s what we actually know. (Vox) |

    These Covid-19 vaccine candidates could change the way we make vaccines — if they work (Vox) |

    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


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    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?

    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, mRNA vaccine, COVID 19 prevention, Pfizer vaccine and Moderna vaccines, Biontech, AstraZeneca Oxford coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • x
  • Coronavirus Update 119: Pfizer BioNTech COVID Vaccine

    14:13

    Professor Roger Seheult, MD discusses details from the CDC that answer many COVID 19 vaccine related questions: Who will be the first to receive the COVID-19 vaccine in the United States? What if you've already had a COVID-19 infection? What type of side effects (or reactogenicity) are being reported? Can pregnant women or immunocompromised people get the vaccine? Is it ok to stop wearing a mask after I receive the vaccine? (This video was recorded on December 14, 2020).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    Use of Pfizer-BioNTech COVID-19 Vaccine: Clinical Considerations (CDC) |

    Find Your Place in the Vaccine Line (New York Times) |

    ACIP Evidence to Recommendations for Use of Pfizer-BioNTech COVID-19 Vaccine under an Emergency Use Authorization (CDC) |

    COVID-19 ACIP Vaccine Recommendations (CDC) |

    CDC greenlights advisory group’s decision to recommend Pfizer vaccine for use (Washington Post) |

    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)
    - Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?

    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, mRNA vaccine, COVID 19 prevention, Pfizer vaccine and Moderna vaccines, Biontech, AstraZeneca Oxford coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • x
  • Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna

    11:49

    Professor Roger Seheult, MD explains the Johnson and Johnson / Janssen Pharmaceuticals vaccine candidate for COVID 19. Dr. Seheult illustrates how the Johnson & Johnson adenovirus vaccine works, the efficacy/safety (based on preliminary data), and how the vaccine compares to the Moderna vaccine and the Pfizer BioNTech vaccine. (This video was recorded on February 4, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    Interviewer: Kyle Allred, Physician Assistant, Producer / Co-Founder of MedCram.com

    LINKS / REFERENCES:

    A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants (NIH) |

    Johnson & Johnson Announces Single-Shot Janssen COVID-19 Vaccine Candidate Met Primary Endpoints in Interim Analysis of its Phase 3 ENSEMBLE Trial (Johnson & Johnson) |

    J&J one-dose Covid vaccine is 66% effective, a weapon but not a knockout punch (STAT) |

    One-shot COVID-19 vaccine is effective against severe disease (ScienceNews) |

    UK COVID Symptom Study |

    Doctor Explains The PREVENTION & TREATMENT For The Coronavirus | Roger Seheult & Lewis Howes (Lewis Howes YouTube Channel) |


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 120: Anticoagulants (Blood Thinners) Improve Hospital Outcomes (Full Dose)
    - Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (Clinical Considerations)
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)
    - Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?

    All coronavirus updates are at ad-free MedCram.com (including this video on the Johnson and Johnson Vaccine).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavirus

  • Oxford-AstraZeneca Covid vaccine has a distinct comparative advantage, Lancet editor says

    3:25

    Richard Horton, editor-in-chief of The Lancet, discusses the efficacy of the Oxford-AstraZeneca coronavirus vaccine shortly after a paper published in the medical journal found it to be safe and effective.

  • x
  • Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine

    14:41

    Professor Roger Seheult, MD discusses the Moderna COVID-19 mRNA vaccine: How it works and what we know about the safety, efficacy, and side effects at this time.

    No mRNA vaccine has ever been approved by the FDA, but Moderna and Pfizer/BioNTech hope to receive emergency approval based on preliminary data from their ongoing vaccine trials.

    Moderna's two-dose vaccine regimen does not require special refrigeration (the Pfizer vaccine is supposed to be stored at -70 Celcius) but a variety of questions remain:
    Will the vaccine prevent transmission and asymptomatic spread?
    How long will immunity last?
    Will “94.5% effective” hold up to peer-review and additional data when it is gathered?

    (This video was recorded on November 17, 2020).

    Dr. Seheult is the co-founder and lead instructor at


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    Outcomes for Out-of-Hospital Cardiac Arrest in the United States During the Coronavirus Disease 2019 Pandemic (JAMA Cardiology) |

    Moderna’s Covid-19 vaccine is strongly effective, early look at data show (STAT) |

    mRNA Platform: Enabling Drug Discovery & Development (Moderna) |

    What is mRNA? (Moderna) |

    Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study (Moderna) |


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)
    - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment
    - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data
    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
    - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe
    - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention?
    - Coronavirus Pandemic Update 105: FDA Authorized Treatments; COVID 19 Vaccine Update
    - Coronavirus Pandemic Update 103: Convalescent Plasma Treatment & the FDA; College Campuses Close

    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, mRNA vaccine, COVID 19 prevention, Pfizer and Moderna vaccines, Biontech, coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Roger Seheult, MD
    Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
    Associate Professor at the University of California, Riverside School of Medicine

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • COVID-19 Vaccines: MODERNA | PFIZER/BIONTECH | ASTRAZENECA

    43:41

    #COVID19 #coronavirus #vaccines

    During this lecture we will be discussing COVID-19 vaccines including Moderna, Pfizer/BioNTech, and Astrazeneca/Oxford.

    We are NOT sponsored and/or endorsed by Moderna, Pfizer/BioNTech, or Astrazeneca. We are presenting on RESEARCH and in no way is any of the information provided our own view or opinions.

    This will be a lecture packed with the process vaccine developers must go through; which includes a preclinical phase and phases I-III. Including information about OPERATION WARP SPEED and how this has expedited the normally lengthy vaccine process.

    We will then discuss how Moderna, Pfizer/BioNTech, and Astrazeneca vaccines work in the human body, preventing the SARS-CoV-2 virus and hopefully, ending this global pandemic.

    Finally-- Zach presents on all of the most current data that each of the vaccine companies have released outlining the vaccine procedure and how it will be administered, the vaccine efficacy (as a percentage), optimal storage temperature of the vaccine in order to remain viable, and the number of vaccine units these companies are capable of producing.

    IMPORTANT INFO (MUST READ):
    One thing to emphasize that wasn’t harped on enough from this lecture is when these vaccines lead to an immunogenic reaction as we described above, which leads to formation of Memory B cells and Memory T cells. This is important because if we are exposed to the virus those memory cells are now primed and able to recognize and mount a powerful immune response against the virus.

    LASTLY, one additional point and clarification is when those cytotoxic T cells produce destructive molecules that damage host cells it’s important to realize that those are memory cytotoxic T cells primed by the Vaccine that damage host cells that ARE INFECTED with the SARS-COV-2 virus, NOT CELLS processing the vaccine.

    Big Takeaway:
    1. Vaccine stimulates antibody production to protect against virus IF INFECTED.
    2. Vaccine stimulates development of memory T and B cells to protect against virus IF INFECTED.

    References |
    Regulatory Affairs Professionals Society (RAPS) COVID-19 Tracker


    Join this channel to get access to perks:


    Support us by purchasing apparel and donating to our GoFundMe or Patreon!

    --Become a Patron of ours and receive the final, high resolution photo of the lecture!

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    @NinjaNerdSci

  • x
  • Coronavirus Update 127: Delta Variant and Vaccines

    18:09

    Professor Roger Seheult, MD of MedCram with an update on the effectiveness of four major vaccines against the delta variant of COVID-19: Pfizer / BioNtech, Moderna, AstraZeneca, and Johnson and Johnson Vaccine (This video was recorded on July 19, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    5 Things To Know About the Delta Variant (Yale Medicine) |

    REACT-1 round 12 report: resurgence of SARS-CoV-2 infections in England associated with increased frequency of the Delta variant (Imperial College) |

    SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness (The Lancet) |

    Vaccines highly effective against B.1.617.2 variant after 2 doses (GOV.UK) |

    Effectiveness of COVID-19 vaccines against hospital admission with the Delta (B.1.617.2) variant (Public Health England) |

    Moderna Provides a Clinical Update on the Neutralizing Activity of its COVID-19 Vaccine on Emerging Variants Including the Delta Variant First Identified in India (Moderna) |

    How much protection COVID-19 vaccines give you against the Delta variant, according to the best available data (Business Insider) |

    The total number and mass of SARS-CoV-2 virions (NIH) |

    Covid vaccine: How many people in the UK have been vaccinated so far? (BBC News) |

    All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #SARSCoV2 #Coronavirus

  • Coronavirus Update 125: Variants, Vaccine Uptake, Sinovac, Brazil, India, Israel

    15:01

    Professor Roger Seheult, MD of discusses the dramatic rise in COVID 19 in Brazil and India, Global Vaccine Update, The Sinovac CoronaVac Vaccine, and new research on coronavirus vaccine efficacy vs. variants in Israel, South Africa, and other locations. (This video was recorded on April 12, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Updates on COVID-19 daily new cases and daily deaths around the world
    00:30 Brazil and India emerge as global “hotspots” for COVID-19
    03:09 International vaccination campaign tracker
    04:05 Mechanism of Sinovac’s COVID-19 vaccine developed in China
    06:42 Efficacy of Sinovac vaccine on different SARS-CoV-2 variants
    08:01 COVID-19 vaccination and infection rates in Chile
    08:50 Three countries to watch carefully: Brazil, India, and Chile
    09:27 Israel among highest in the world for COVID-19 vaccine coverage
    09:48 Is Pfizer vaccine becoming less effective against South African variant in Israel?
    12:39 Serious COVID-19 cases in Israel fall below 300 for first time since December
    13:13 Could low vaccination rate be responsible for high COVID-19 death rate in Brazil?
    14:15 What to do if COVID-19 cases are surging near you


    LINKS / REFERENCES:

    Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna (MedCram) |

    If You Get COVID 19: Optimize Immune System (MedCram) |

    Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (MedCram) |

    Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (MedCram) |

    Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (MedCram) |

    Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (MedCram) |

    More Than 781 Million Shots Given: Covid-19 Tracker (Bloomberg) |

    How the Sinovac Vaccine Works (NYT) |

    Sinovac: Brazil results show Chinese vaccine 50.4% effective (BBC News) |

    Israeli data shows South African variant able to ‘break through’ Pfizer vaccine (The Times of Israel) |

    Pfizer Covid Vaccine Protects Against South African Variant, ‘Highly Effective’ Against Disease For Six Months, Updated Trial Data Shows (Forbes) |

    Pfizer and BioNTech Confirm High Efficacy and No Serious Safety Concerns... (Pfizer) |

    India bans remdesivir exports as COVID-19 cases surge (Aljazeera) |

    Chile Covid-19 vaccination drive adds to Sinovac efficacy data (S. China Morning Post) |

    Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals (medRxiv) |

    Covid-19: Why have deaths soared in Brazil? (BBC News) |

    All coronavirus updates are at MedCram.com (including more discussion on COVID variants, Sinovac, CoronaVac, COVID mutations, California variant, coronavirus variant, vaccine uptake, and more).


    SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL:


    Get notified of new videos by hitting the bell icon:


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavirus

  • How the AstraZeneca COVID-19 vaccine has performed so far

    3:12

    Important details about the newly approved Oxford-AstraZeneca vaccine for COVID-19, like how well it works and what we've learned from other countries already using it.

    Watch The National live on YouTube Sunday-Friday at 9 p.m. ET

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  • x
  • COVID Variants vs. Coronavirus Vaccines + Immunity

    54:25

    Renowned virologist Shane Crotty, PhD joins us again to address the most important COVID-19 questions: Should people who’ve been vaccinated or had COVID-19 continue to wear masks and physically distance? How will each vaccine hold up to the SARS-CoV-2 variants? What does the research say about people who’ve already had COVID-19 who get a vaccine? How long will immunity last for the vaccines or COVID-19 infection?

    Shane Crotty is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Prof. Crotty also has an academic appointment with the University of California San Diago. See his full bio here:
    Prof. Crotty on Twitter:

    Interviewer: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com

    (This video was recorded on March 23, 2021)

    Just to clarify at 8:40 in the video: Prof. Crotty is describing a theoretical person when he says I myself am comfortable getting infected... He hasn't had COVID, and doesn't have that opinion. He was explaining one end of the spectrum of level of concern for individuals.

    TOPICS DISCUSSED IN THIS VIDEO INCLUDE:

    0:00 Intro
    0:46 Heated exchange between Dr. Fauci and Senator Rand Paul
    1:00 How long does immunity last for those who’ve had COVID-19?
    3:31 How antibody levels and T cells drop over time
    4:03 Dr. Fauci: Difference between in vitro and real-world studies
    4:36 Population-based studies about COVID 19 immunity against reinfection
    6:22 Huge variability from person to person for post coronavirus immunity
    8:20 Policy decision: individual vs. community goals during a pandemic
    9:03 Very rare for hospitalization from COVID-19 reinfection
    9:34 Avoiding COVID-19 infection and transmission potential
    10:12 Should mask-wearing continue for those who’ve had COVID-19?
    12:23 If I’ve had COVID-19, shouldn’t my vaccine dose go to someone else?
    13:39 Vaccines are eliciting more immunity than natural infection
    14:02 Is natural immunity always better than a vaccine?
    20:05 If you’ve had COVID-19, when should you get vaccinated? Both doses?
    22:07 How are variants “game changers” for vaccines and natural infections?
    24:53 Can’t I stop wearing masks and distancing after a vaccine or having COVID?
    26:14 Variants of concern: B.1.1.7 (UK) and B.1.351 (S. Africa) details and implications
    30:57 South Africa Variant escaping immunity: AstraZeneca Vaccine data
    32:28 Isn't preventing COVID 19 hospitalizations and deaths the primary goal?
    35:25 Will we need updated coronavirus vaccines?
    36:38 Johnson and Johnson vaccine versus the variants
    37:57 Preventing transmission to prevent SARS CoV 2 mutation opportunities
    38:40 Coronavirus antibodies vs T Cells and other parts of the immune system
    39:54 Replication and asymptomatic spread of COVID-19 vs. Pneumonia
    42:53 Vaccine incentives and Senator Rand Paul's perspective
    45:35 Looking ahead, SARS-CoV-2 vs Influenza, Will we need annual vaccinations?
    52:20 Current research and goals for Prof. Shane Crotty

    PREVIOUS MEDCRAM DISCUSSIONS WITH PROF. CROTTY :
    (Dec 16, 2020)
    (January 5, 2021)

    REFERENCES:

    Crotty's Research Published in Science |

    Variant Tracker |

    Denmark Research in the Lancet |

    UK SIREN study:

    Research from Qatar |

    UK Research in NEJM |

    Qatar:

    Congressional Hearing 3/8/21: exchange with Dr. Fauci and Rand Paul: (PBS News Hour) and (CNBC)


    THE MEDCRAM WEBSITE:

    Visit us for videos on over 60 medical topics and CME / CEs for medical professionals:

    All coronavirus updates are at MedCram.com ad-free (including more on RNA vaccines, COVID variants, South African Variant, Johnson and Johnson vaccine for COVID 19, and more):


    MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS:

    MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #Coronavirus #COVID19UK

  • Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained

    22:32

    Professor Roger Seheult, MD discusses the Pfizer / Biontech COVID-19 mRNA vaccine: How it works and what we know about the safety and efficacy at this time.

    No mRNA vaccine has ever been approved by the FDA, but Pfizer and BioNTech hope to receive emergency approval based on preliminary data from their ongoing vaccine trial.

    This two-dose vaccine regimen has limitations including the need for -70 C refrigeration and many questions remain:
    Will the vaccine prevent transmission and asymptomatic spread?
    How long will immunity last?
    Will “90% effective” hold up to peer-review and additional data when it is gathered?

    (This video was recorded on November 12, 2020).

    Dr. Seheult is the co-founder and lead instructor at


    LINKS / REFERENCES:

    Johns Hopkins Tracker |

    Worldometer |

    COVID-19 vaccine tracker (RAPS) |

    Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates (NEJM) |

    A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates (bioRxiv) |

    Pfizer and BioNTech Announce Vaccine Candidate Against COVID-19 Achieved Success in First Interim Analysis from Phase 3 Study (BioNTech) |

    Why mRNA represents a disruptive new drug class {BioNTech) |


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    - Coronavirus Update 113: Remdesivir May Not Work for COVID 19
    - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data
    - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC
    - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon
    - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise
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    All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, COVID 19 prevention, Pfizer vaccine, Biontech, coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more).
    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


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    #COVID19 #SARSCoV2

  • DNA vaccines explained: The future of vaccination? | COVID-19 Special

    12:05

    Right now everyone is talking about mRNA vaccines, such as the Biontech-Pfizer or the Moderna vaccine - but what about DNA-vaccines? Will this be a vaccine type of the future?

    Vaccines have saved millions of lives in the past century and for now, they're the best way out of this crisis. There are exciting new prospects, waiting in the wings. The practice of vaccinating dates back thousands of years through rabbit spines, powdered cowpox and fearless scientists. Today, viral vectors and mRNA technology have been instrumental in fighting COVID-19. With DNA vaccines another technique is already been tested.

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    #dnaVaccine #vaccination #coronavirus

  • mRNA Vaccines - Layman’s version , plus some FAQs, Animation.

    4:48

    The basis of upcoming Pfizer and Moderna coronavirus RNA vaccines. How it works? Plus some FAQs: Does mRNA vaccine change my DNA? Why do people want me to take the vaccine?
    For comparison of different vaccines, as well as events of immune response, role of different immune cells (T-cells, B-cells, APC), see this video:
    This video is available for instant download licensing here:
    ©Alila Medical Media. All rights reserved.
    Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
    All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
    The purpose of a vaccine is to mimic an infection, activating the body’s immune response, but without causing the illness. Conventional vaccines usually contain a weakened or inactivated virus; or a piece of a viral protein, called an antigen. These viral elements do not cause disease, but they trick the immune system into thinking that an infection has occurred so that it responds by producing antibodies against the virus. RNA vaccines are a new generation of vaccines. Instead of a protein antigen, they contain mRNA, meaning messenger RNA. As its name suggests, mRNA is basically a messenger, carrying genetic message from DNA to protein. In order to function, a human cell needs to constantly produce proteins based on genetic information in its DNA. Because DNA is located in the nucleus of the cell, and protein synthesis occurs in the cytoplasm, an intermediate molecule is required to transmit the information. mRNA copies the information from DNA and brings it to the cytoplasm, where it is translated into protein. mRNA consists of 4 basic building blocks called A, U, C and G. The information it carries is the sequence of these letters. RNA vaccines contain mRNA strands that have the information for making the viral antigen, usually a viral spike protein. Once inside the body’s cells, the mRNA is translated into protein, the antigen, by the same process the cells use to make their own proteins. The antigen is then displayed on the cell surface where it is recognized by the immune system. From here, the sequence of events is similar to that of a conventional vaccine. RNA vaccines are easier and safer to produce than conventional vaccines. Conventional vaccines typically require growing large amounts of infectious viruses, usually in chicken eggs, and then inactivating them. Vaccines produced this way are at risks of being contaminated with LIVE viruses and allergens from egg culture. Such risks do NOT exist with RNA vaccines because mRNA molecules can be synthesized in a CELL-FREE system using a DNA template that contains information for making the viral protein. The mRNA is made from the same building blocks as natural mRNA, so it has the same chemical composition as natural mRNA. The relative simplicity of the production process makes it easier to standardize and scale, enabling rapid responses to emerging pandemics. In case the virus MUTATES, it’s also simple to change the mRNA sequence to match the mutation. Will RNA vaccines change my DNA? RNA vaccines do NOT change your DNA. This is because in order to do so, the mRNA must convert into DNA, enter the nucleus, and integrate into the cell’s DNA. This is a complex multiple-step process requiring action of several enzymes that the cell does NOT have. Instead, the cell has plenty of enzymes that can readily destroy the mRNA, so the mRNA is usually degraded after the protein is made. Why do people try so hard to convince others to take vaccine? The answer is herd immunity. When enough people in a community are vaccinated, the whole community, including the individuals that were not vaccinated, is protected against the disease. This phenomenon is known as herd immunity. Herd immunity is possible because a pathogen cannot spread without a sufficient number of vulnerable hosts. An analogy is the spread of wildfires. A wildfire only spreads where there is vegetation, or fuel, for it to burn; it would stop at a river, or a large open space. These are called firebreaks. Vaccinated individuals essentially serve as firebreaks, preventing spread of infections caused by pathogens. Herd immunity is important because not everyone can be vaccinated. Often, the very young, very old, and immunocompromised people must rely on vaccinated individuals to stop disease outbreaks. To note, however, that the number of vaccinated individuals must be great enough for community protection to occur, just like a firebreak must be large enough to stop a fire.

  • EU decides to not renew AstraZeneca Covid-19 vaccine order | Biontech Pfizer | Latest English News

    3:24

    The European Union has seemingly decided not to renew its deal with pharmaceutical giant AstraZeneca for its Covid-19 vaccine according to a leading official.

    #Astrazeneca #EU #COVID19

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  • Coronavirus Vaccines - An Introduction

    9:54

    Leading COVID-19 vaccine candidates rely on new technologies that have fast-tracked development and testing. Vaccines from Pfizer and Moderna have completed early phase 3 clinical trials and are reportedly under review at the US FDA for emergency use authorization (EUA) although safety surveillance continues. This video explains the principles underlying the leading DNA, messenger RNA (mRNA), and viral vector vaccine candidates, and how they might induce immunity to SARS-CoV-2 infection.

    0:00 Introduction
    1:21 Traditional vaccines
    2:00 COVID-19 vaccine types in development
    2:18 Making vaccines from a genetic sequence
    2:45 Target antigen: the S protein
    3:32 Genetic vaccines (DNA and mRNA)
    4:18 Moderna/NIH and Pfizer/BioNTech vaccines
    4:52 Viral vector vaccines
    5:42 Adenovirus vectors (University of Oxford/AstraZeneca and Johnson & Johnson/Janssen Pharmaceuticals)
    6:32 rVSV vector vaccine (Merck/IAVI)
    7:15 Previous experience with next generation vaccines
    7:50 Importance of Phase 3 Trials

    For full livestreams featured in this video:
    Anthony S. Fauci, MD, January 27, 2020:
    Paul A. Offit, MD, June 1, 2020:
    Robert Redfield, MD, July 14, 2020:

    ---------------------------------------------------------------------------------

    • Coronavirus Resource page from the JAMA Network:
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    • Don't forget to hit subscribe or click

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  • COVID-19: UK Study Suggests 2 Doses Of Pfizer, AstraZeneca Vaccines Effective Against Delta Variant

    1:49

    #Pfizer #AstraZeneca #COVIDVaccine #COVID19 #COVID #Coronavirus #RepublicTV

    Even as the Delta variant (B.1.617.2) is now spreading rapidly across the world, a UK-based study has found that vaccines are highly effective against this COVID-19 strain. This assumes significance as the National Centre for Disease Control had concluded that this variant was responsible for the second wave in India. First detected in India, the Delta variant has been listed as a variant of concern by the WHO. The aforesaid study was conducted by Public Health England- an executive agency of the UK's Department of Health and Social Care between April 12 and June 4.

    It entailed an analysis of 14,019 cases of the Delta variant out of which 166 persons were admitted to hospitals in the UK. While 96% of persons taking two doses of the Pfizer-BioNTech vaccine were protected from hospitalization, the corresponding finding for the Oxford-AstraZeneca vaccine is 92%. Thus, these are comparable with vaccine effectiveness against hospitalization from the Alpha variant. However, the level of protection from mortality from the Delta variant is yet to be established. Reacting to this development, UK Health and Social Care Secretary stressed the importance of getting the second dose of the vaccine.

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  • How Does AstraZeneca Compare With Moderna & Pfizer? Answers Oxfords Adrian VS Hill | Exclusive

    6:22

    DCGI has approved Oxford COVID-19 vaccine Covishield, manufactured by the Serum Institute. Speaking exclusively on the show Newstrack with Rahul Kanwal, Oxford's Adrian VS Hill shared his view about the efficacy of Covishield, Making of Covid vaccine & roll-out plans. He answered the question - How does AstraZeneca compare with Moderna and Pfizer? Watch full bulletin.

    #AdrianHill #Covaxin #Covishield #Coronavirus #CovidVaccine #IndiaToday #RahulKanwalExclusive #Newstrack

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  • Coronavirus Vaccine:DNA & mRNA. AstraZeneca, Pfizer and Moderna

    2:57

    This educational video explains the genetic vaccines using DNA & mRNA.

  • Coronavirus mRNA Vaccine Safety and Efficacy

    9:37

    Millions of people are now being immunized with mRNA vaccines from Pfizer-BioNTech and Moderna. Both vaccines have very high efficacy and look safe in the short-term. This video reviews experience with the vaccines since they were authorized for use in December 2020. (Produced February 2021).

    0:00 Introduction
    0:26 How mRNA vaccines work
    2:11 Efficacy
    2:56 Prevention of symptoms vs infection and transmission
    5:00 Safety
    5:43 Post-authorization safety surveillance
    6:39 Data on anaphylactic reactions
    7:26 Experience since authorization

  • COVID 19 Vaccine Deep Dive: Safety, Immunity, RNA Production,

    34:29

    Professor Shane Crotty, PhD joins MedCram to answer a series of COVID vaccine questions including what are the chances of long-term side effects? How safe is RNA vaccine (i.e. Pfizer / BioNTech and Moderna Vaccines) technology? How long does mRNA from a vaccine stay in our cells? What else goes in vaccines? How long does immunity last? Why are T-Cells so important? Why does Pfizer's vaccine need to stay SO cold?

    Shane Crotty, PhD is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Professor Crotty also has an academic appointment with the University of California San Diego. See his full bio here:
    Professor Crotty on Twitter:

    Interviewer: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com

    See our new interview with Prof. Crotty on how virus mutations (UK variant and S. African variant) may be impacting COVID-19 transmission and vaccine efficacy.

    Research referenced in this video from Prof. Crotty and his team was published Jan. 6, 2021, in the prestigious Journal Science:

    New York Times article highlighting Prof. Shane Crotty's research:

    00:00 Introducing Prof. Shane Crotty's Research
    0:35 How long does COVID-19 immune memory last?
    0:57 The three primary aspects of immune memory: antibodies, killer T cells, and helper T cells
    2:25 The anatomy (protein makeup) of SARS-CoV-2
    3:02 Why is spike protein the primary target?
    5:17 Could a mutation allow SARS-CoV-2 to infect without spike protein?
    7:02 Utilizing lipid nanoparticles to deliver mRNA and the role of RNA normally
    9:52 What human cells does an RNA vaccine go into?
    10:36 How long does mRNA from a vaccine stay in human cells?
    11:44 What else goes in vaccines besides mRNA and lipid nanoparticles? Any preservatives or adjuvants?
    12:30 Why are adjuvants used in many vaccines?
    14:08 Protein production from mRNA
    15:00 Why utilize the extra step of mRNA to code for protein antigens?
    17:28 Are mRNA vaccines the future of vaccine development?
    19:18 Any chance for mRNA to enter our cells' nucleus?
    20:55 The immune response to a coronavirus vaccine
    23:17 Expected symptoms from immune response to a vaccine vs. vaccine side effects
    25:50 Should people who've had COVID-19 get vaccinated?
    27:27 Immunity from COVID vaccine vs. a natural infection
    28:30 Why does the Pfizer vaccine need to be stored so cold?
    29:04 What would you say to a family member who is nervous about a rushed vaccine and RNA technology?
    32:37 What about the possibility of long term side effects from RNA vaccines?
    33:30 What's next for Shane Crotty's research team?

    (This video was recorded on December 16, 2020).

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    PREVIOUS / RECENT MEDCRAM COVID-19 INTERVIEWS:

    Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD

    At Home COVID 19 Antigen Testing and Vaccine Update with Professor Michael Mina, MD

    All coronavirus updates are at MedCram.com ad-free (including more videos on the Pfizer vaccine, Moderna vaccines, BioNTech vaccine, vaccine side effects, COVID 19 vaccine mechanism, AstraZeneca Oxford coronavirus vaccine, side effects of COVID 19 vaccine, COVID 19 treatments, and more):

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    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2 #Coronavaccine

  • x
  • How viral vector and mRNA COVID-19 vaccines work

    1:23

    From viral vector vaccines like AstraZeneca to mRNA vaccines like Pfizer and Moderna, they all have the same goal: to train your body how to fight off COVID-19. But, they use different strategies to create antibodies.

    For example, AstraZeneca uses a crippled virus to deliver the coronavirus spike protein, while Pfizer and Moderna use mRNA, the part of the coronavirus' genetic code and teaches your cells how to make a protein that will trigger an immune response.

    Global’s Gloria Henriquez explains how the different COVID-19 vaccines available in Canada work.

    For more info, please go to
    Subscribe to Global News Channel HERE:
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    #GlobalNews #COVIDvaccines

  • Coronavirus Update 123: COVID 19 Vaccines vs. Variants

    10:42

    How well will COVID-19 vaccines work against the coronavirus variants first discovered in the UK, South Africa, and Brazil? Dr. Seheult discusses the research we have so far on SARS CoV 2 mutations. (This video was recorded on February 23, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    COVID: UK variant spreading rapidly in Germany (DW) |

    Germany: Schools reopen for younger children amid rising COVID infections (DW) |

    Where schools are reopening in the US (CNN) |

    Adapted booster vaccines in the works (Medical News Today) |

    Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera (Science) |

    Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera (Cell) |

    mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants (bioRxiv) |

    Moderna COVID-19 Vaccine Retains Neutralizing Activity Against Emerging Variants First Identified in the U.K. and the Republic of South Africa (Moderna) |


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    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 122: The Research So Far on COVID-19 and Vaccines vs. Pregnancy
    - Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna
    - Coronavirus Update 120: Anticoagulants (Blood Thinners) Improve Hospital Outcomes (Full Dose)
    - Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (Clinical Considerations)
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna mRNA vaccines)

    All coronavirus updates are at MedCram.com (including more discussion on COVID variants, COVID mutations, and more).

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


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    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred

    FOLLOW US ON SOCIAL MEDIA:






    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • Head To Head: The Oxford And Pfizer Covid Vaccines Compared

    2:34

    With India just a few days away from an expected approval on Covid vaccines we did a head to head comparison on the frontrunners - Pfizer and Oxford. Here, we compare the vaccines on four parameters - Efficacy, technology, storage and price.

    NDTV is one of the leaders in the production and broadcasting of un-biased and comprehensive news and entertainment programmes in India and abroad. NDTV delivers reliable information across all platforms: TV, Internet and Mobile.

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  • How do mRNA COVID-19 vaccines work?

    2:28

    The first COVID-19 vaccines represent an incredible record-breaking achievement in vaccine development. Not only were the Moderna and Pfizer/BioNTech vaccines created in record time, they also harness a never-before-used technology: immunization through mRNA. But how do these vaccines protect us and how do they differ from other vaccines? These first mRNA vaccines may pave the way for faster, more efficient vaccine development in the future.

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  • Singapore’s 3 COVID-19 Vaccines – And Is One Better Than The Others?

    3:40

    Singapore has ordered the Pfizer-BioNTech, Moderna and Sinovac vaccines as the first three of its portfolio in the fight against the coronavirus pandemic.

    ALSO WATCH: Is the vaccine safe? Your questions answered

    Both the Pfizer-BioNTech (also in use in Britain and the US) and Moderna (used in the US) vaccines use messenger RNA (mRNA) technology that involves injecting snippets of the COVID-19 genetic code, triggering an immune response without actually exposing the patient to the virus. Both vaccines are said to have an efficacy rate of about 95%.

    The China-made Sinovac vaccine uses an inactivated COVID-19 virus to trigger an immune response. There is a lack of specific results on its efficacy at the moment. As of January 7, 2020, the Sinovac vaccine has not been used in any country.

    Co-chair of the COVID-19 multi-ministry task force Lawrence Wong tells #TalkingPoint why the Singapore Government convened an expert panel as early as April 2020 to look into early purchases of COVID-19 vaccines based on early-stage clinical information.

    Director of communicable diseases at the Ministry of Health (MOH) Vernon Lee said “all the vaccines approved in Singapore are safe and efficacious”, but that some may be more suited to certain subpopulations. The Pfizer vaccine for instance - the only one in use in Singapore as of Jan 8 - is not for use in those with severe allergic reactions.

    ALSO WATCH:
    The Search For A COVID-19 Vaccine:
    Inside Coronavirus Human Vaccine Trials In Singapore:
    Is A Safe COVID-19 Vaccine By 2021 Really Possible?:


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  • Top 8 Vaccines for Covid-19 | Comparison

    3:29

    In this video we have discussed about the Vaccines globally present for the Covid-19.
    These 8 vaccines shows the efficacy of 60-90 % depending upon the variant we are targeting. The top 8 vaccines that we have currently present includes the :
    Pfizer BioNtech
    Moderna
    Johnson and Johnson
    Astrazeneca /Covisheild
    Sputnik V
    Novavax
    Covaxin
    Sinovac/Coronavac

  • Coronavirus COVID 19 Oxford AstraZeneca Vaccine Information

    20:31

    Pharmacist Abraham, discusses Coronavirus Vaccine. COVID 19 Vaccine. Oxford Vaccine. AstraZeneca Vaccine. How it Works, Safety, Pregnancy, Side Effects and Lots More.

    In this weeks video we’re looking at the Coronavirus COVID 19 Oxford AstraZeneca Vaccine. This video consists of the current information on the 23rd of January 2021 that we have on the Oxford AstraZeneca COVID 19 Vaccine.

    VIDEO BREAKDOWN:
    00:00 Coronavirus COVID 19 Oxford AstraZeneca Vaccine Information
    01:04 How does the Oxford AstraZeneca Coronavirus COVID 19 Vaccine work
    05:04 Oxford AstraZeneca Coronavirus COVID 19 Evidence & Clinical Trials
    07:38 How is the Oxford AstraZeneca Coronavirus COVID 19 Vaccine Given
    08:21 Who can get the Oxford AstraZeneca Coronavirus COVID 19 Vaccine
    10:13 Who can't get the Oxford AstraZeneca Coronavirus COVID 19 Vaccine
    11:26 Oxford AstraZeneca Coronavirus COVID 19 Vaccine in Pregnancy and Safety
    14:02 Side effects and safety of Oxford AstraZeneca Coronavirus COVID 19 Vaccine
    17:13 How long will the Oxford AstraZeneca Coronavirus COVID Vaccine be effective
    18:05 Final thoughts on Oxford AstraZeneca Coronavirus COVID Vaccine

    IMPORTANT INFORMATION:
    As mentioned in the video all of the information in this video is relevant and up to date on the date of filming 23rd of January 2021 - This information can change with time, therefore the best way to keep up to date with the latest information about the Coronavirus Vaccine is via the reputable health sources below who currently have dedicated pages on Coronavirus which is constantly updated with new information.





    CORONAVIRUS COVID 19 VACCINE:
    The coronavirus (COVID-19) vaccine is safe and effective. It gives you the best protection against coronavirus.

    The NHS is currently offering the COVID-19 vaccine to people most at risk from coronavirus. For the most up to date list please visit the NHS link above.

    The NHS will let you know when it's your turn to have the vaccine. It's important not to contact the NHS for a vaccination before then.

    CORONAVIRUS COVID 19 VACCINE SIDE EFFECTS:
    Most side effects of the COVID-19 vaccine are mild and should not last longer than a week, such as:
    • A sore arm where the needle went in
    • Feeling tired
    • A headache
    • Feeling achy
    • Feeling or being sick

    You can take painkillers, such as paracetamol, if you need to.

    If you have a high temperature you may have coronavirus or another infection. Please remember you cannot get COVID 19 from the COVID 19 vaccine however you may have caught COVID 19 prior or after your vaccine date.

    CORONAVIRUS COVID 19 SYMPTOMS:
    If you have any of the main symptoms of coronavirus (COVID-19), get a test as soon as possible. Stay at home until you get the result.

    The main symptoms of coronavirus are:
    • A high temperature – this means you feel hot to touch on your chest or back (you do not need to measure your temperature)
    • A new, continuous cough – this means coughing a lot for more than an hour, or 3 or more coughing episodes in 24 hours (if you usually have a cough, it may be worse than usual)
    • A loss or change to your sense of smell or taste – this means you've noticed you cannot smell or taste anything, or things smell or taste different to normal

    Most people with coronavirus have at least 1 of these symptoms. If your symptoms get worse or you are worried, call 111

    ALLERGIC REACTIONS:
    Tell healthcare staff before you are vaccinated if you've ever had a serious allergic reaction (anaphylaxis - symptoms on video).

    You should not have the vaccine if you've ever had a serious allergic reaction to:
    • A previous vaccine
    • An anaphylactic reaction to any of the ingredients in the COVID 19 vaccine. Please find ingredients list:
    • A previous dose of the same COVID-19 vaccine
    • Some medicines, household products or cosmetics

    YELLOW CARD REPORTING:
    As mentioned in the video here is the link to report any side effects:

    COVID 19 VACCINE AND PREGNANCY:
    As explained in the video please stay up to date with the current information on this topic from the following reputable health sources,



    DISCLAIMER:
    This video is for information only and should not be used for the diagnosis or treatment of medical conditions. Abraham The Pharmacist has used all reasonable care in compiling the information but make no warranty as to its accuracy. Always consult a doctor or other healthcare professional for diagnosis and treatment of medical conditions.

  • Covid-19 vaccines: Moderna vs. Pfizer vs. Johnson & Johnson comparison

    8:24

    We asked Dr. Stephen Thomas, chief of Infectious Diseases at SUNY Upstate Medical University, what we need to know about the vaccines right now and what we could learn in the coming months.

    Watch the video for a deeper explanation about the three vaccines currently available in the U.S. — Moderna, Pfizer/BioNTech and Johnson & Johnson. Moderna and Pfizer are messenger RNA, or mRNA vaccines and Johnson & Johnson is a viral vector vaccine. All three are designed to protect against Covid-19.

    According to the CDC, rather than inject the body with a weakened version of the coronavirus, these vaccines teach the body to make a protein which triggers an immune response. It’s those antibodies that our bodies produce that help keep us safe when confronted with the actual virus.

    Side Effects
    The mRNA vaccines have been administered to over 80 million people in the United States and they are safe and effective, Thomas said. Thomas was the lead principal investigator for the worldwide Pfizer/BioNTech vaccine trial.

    In data from the trials, Thomas noted, “The safety profile of these vaccines are all pretty similar, most people will experience some kind of pain at the site the vaccine was injected and most people say the pain is mild to moderate.

    Dr. Thomas also mentioned these other common side effects:
    • Mild to moderate headache
    • Mild to moderate fatigue
    • 30 to 40 percent of people might have muscle aches or joint pain
    • About ten to fifteen percent of people might develop a fever

    “The good news is if it’s going to happen to you, because it doesn’t happen to everyone, it happens pretty soon after you get vaccinated and once it starts it goes away within a couple of days,” Thomas said.

    “With Pfizer and Moderna rolling out over 80 million doses of vaccine the side effects continue to be the same as the data from the trials and we aren’t seeing any new side effects or more severe side effects,” he added.

    What about the variants?
    Work is being done in laboratories with the Moderna and Pfizer vaccines, testing people’s antibodies to see if the antibodies will neutralize the variants.

    Thomas said, “They are not as good at neutralizing those variants as they are against the predominant strain in the United States which is from China. But experiments are continuing and there is some concerning data there, which is why it’s important that we vaccinate as many people as possible, because it’s a race against the variants.”

    Thomas noted that the vaccines are still working at fifty to sixty-percent efficacy against the new variants.

    “Just to put it in context, the annual flu vaccine is about forty-five percent efficacious,” he said.

    How important is the two-dose vaccine time schedule?
    Thomas said it’s important to get these vaccines as close to the schedule as possible as they were tested in the trials. If a change is unavoidable, Thomas recommends delaying the second dose rather than getting it ahead of schedule.

    What is herd immunity and when will we have it?
    Herd immunity is achieved when enough of the population has become immune to a disease (generally through vaccinations) that it makes it difficult for that disease to spread.

    That would mean even those who are not immune would be protected.

    “Right now, about fifteen percent of the country has received at least one dose of vaccine, but that’s a far cry from the 70 to 80-percent that we are going to need to achieve herd immunity,” Thomas said.

    Thomas doesn’t think it’s going to be a vaccine supply issue, but more of a willingness for people to be vaccinated. “We’re vaccinating 2 million people a day, if that were to go to 3 million, and we have 320 million people in the country, we could achieve herd immunity by late summer.”

  • Intersections #8: HIV and COVID-19 – DNA Vaccine

    14:03

    amfAR-funded HIV researcher Dr. Dan Barouch of Harvard Medical School and Beth Israel Deaconess Medical Center talks to amfAR’s Dr. Rowena Johnston about his team’s efforts to rapidly develop a vaccine against the coronavirus. Dr. Barouch describes the complex challenges involved in developing , testing and scaling up production of a vaccine that is both safe and effective.

  • Moderna vs., Pfizer-BioNTech Vaccines - An Initial Comparison

    15:46

    Moderna Vaccine Recommended by The FDA Advisory Committee

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    Today the vaccine and related biological products advisory committee (VRBPAC) met to review and recommend the Moderna’s mrna-1273 vaccine for COVID-19. The committee recommended the issuance of emergency use authorization (EUA) with a 95% yay.

    Moderna’s EUA request (presentation):



    The voting question was:

    Based on the totality of scientific evidence available, do the benefits of the Moderna COVID-19 Vaccine outweigh its risks for use in individuals 18 years of age and older?

    Again 95% said yes to the above statement.

    FDA’s meeting presentation



    FDA’s meeting information and material



    FDA’s briefing document


    FDA’s meeting announcement


    #drbeen #koolbeens #COVID19

  • The COVID-19 Vaccines from Pfizer-BioNTech and Moderna: Whats in Them and How Do They Work?

    12:48

    Learn about the composition and delivery mechanism of the two newly available COVID-19 vaccinations from Pfizer-BioNTech and Moderna with Dr. Jonathan Genzen, COO of ARUP Laboratories and an Associate Professor at the Universtity of Utah School of Medicine.

  • Why doctors are concerned about the Oxford/Astrazeneca vaccine

    6:01

    Matt Herper of Stat News joins 'Closing Bell' to discuss President Trump weighing the decision to fast track for the Astrazeneca vaccine and the concerns surrounding that decision. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

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  • Dr Norman Swan looks at the latest advice on the AstraZeneca COVID-19 vaccine | 7.30

    6:32

    The expert advisory group on immunisation is now urging younger people to talk to their doctor about getting the AstraZeneca vaccine if they live in an outbreak zone. It’s also updated its advice on early second doses of the vaccine.

    Dr Norman Swan takes a look.

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  • mRNA vaccines, explained

    6:48

    Why some Covid-19 vaccines were developed faster than any vaccine ever.

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    Researchers working on Covid-19 vaccines have smashed speed records, bringing new vaccines from development to distribution in less than a year. They did this with the help of billions of dollars of unprecedented global investment -- but also, in some cases, with a new type of vaccine technology.

    There are four traditional types of vaccines, and they all require the growing and handling of live pathogens in a lab, a time-consuming process than can add months or years to development. But two new types of vaccines skip that step altogether by moving that work from the lab to our bodies. mRNA vaccines, like the ones from Pfizer-BioNTech and Moderna; and Adenovirus vaccines, like those from Johnson & Johnson and AstraZeneca; do this by sending genetic instructions directly into our cells, which then produce the harmless protein the body needs to learn to fight Covid-19. Because these proteins are produced from within cells rather than injected from the outside, they may be less likely to provoke adverse reactions in the recipient.

    The result has been a host of vaccines developed faster than ever. But it's also ushered us into a new age of vaccine technology, one in which we can send our own bodies the instructions on how to protect themselves. That technology is already being used to drive research on vaccines for HIV and cancer. These new types of vaccines are weapons we developed to fight the coronavirus - but their real impact is just beginning.

    Note: The headline on this video has been changed.
    Previous title: How the newest vaccines fight Covid-19

    Further reading:
    Our original article on Vox.com by Umair Irfan:

    A breakdown of the types of vaccines:

    Infographic on the differences between mRNA vaccines and traditional vaccines:

    The New York Times has a really wonderful in-depth breakdown of how each of the vaccines work:

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  • What Is An mRNA Coronavirus Vaccine?

    17:03

    More than 30 biotech and pharmaceutical companies around the world are racing to develop a safe Covid-19 vaccine. The process is moving quickly with several vaccine candidates entering late-stage trials in a matter of months. Two of the companies developing a vaccine — Pfizer and Moderna — are utilizing a promising new technology called messenger RNA. Watch the video to learn why experts believe this vaccination method could be a game-changer for getting back to normal.

    CORRECTION At 0:30, this video misstated the number of companies chosen by the White House to receive ‘fast track’ designation from Operation Warp Speed. Vaccine projects from Sanofi, in partnership with GSK, and Novavax also received fast-track status.

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    What Is An mRNA Coronavirus Vaccine?

  • RNA Vaccines - Basis of Pfizer and Moderna COVID-19 vaccines, Animation

    3:19

    The basis of upcoming Pfizer and Moderna coronavirus vaccines. How it works? Pluses and minuses. For comparison of different vaccines, as well as events of immune response, role of different immune cells (T-cells, B-cells, APC), see this video:
    This video is available for instant download licensing here:
    ©Alila Medical Media. All rights reserved.
    Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
    All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
    Vaccines prepare the immune system, getting it ready to fight disease-causing organisms, called pathogens. A vaccine is introduced to the body to mimic infection, triggering the body to produce antibodies against the pathogen, but without causing the illness. Conventional vaccines usually contain a weakened or inactivated pathogen; or a piece of a protein produced by the pathogen, called an antigen.
    RNA vaccines are a new generation of vaccines. Instead of the antigen itself, RNA vaccines contain a messenger RNA – mRNA - that encodes for the antigen. Once inside the body’s cells, the mRNA is translated into protein, the antigen, by the same process the cells use to make their own proteins. The antigen is then displayed on the cell surface where it is recognized by the immune system. From here, the sequence of events is similar to that of a conventional vaccine.
    Some RNA vaccines also contain additional mRNA coding for an enzyme, which, after being translated in host cells, can generate multiple copies of the antigen-encoding mRNA. This essentially amplifies the production of antigen from a small amount of vaccine, making the vaccine more effective. These are called self-amplifying RNA vaccines.
    RNA vaccines are easier and safer to produce than conventional vaccines. This is because mRNA molecules can be synthesized in a cell-free system using a DNA template with a sequence of the pathogen; while conventional vaccines usually require a more complicated and risk-prone process of growing large amounts of infectious pathogens in chicken eggs or other mammalian cells. Without the risks of being contaminated by infectious elements or allergens from egg cultures, RNA vaccines are also safer for patients.
    Because protein synthesis occurs in the cytoplasm, RNA molecules do not need to enter the nucleus, so the possibility of them integrating into the host cell genome is low. RNA strands are usually degraded by cellular enzymes once the protein is made.
    The relative simplicity of the production process makes it easier to standardize and scale, enabling rapid responses to emerging pandemics. Other advantages include lower production costs, and the ease of tweaking RNA sequences to adapt to rapidly-mutating pathogens.
    On the minus side, it can be challenging to deliver mRNA effectively to the cells, since RNA sequences and secondary structures may be recognized and destroyed by the innate immune system as soon as they are administered intravenously. These limitations can be overcome by optimizing codons, using modified nucleosides to avoid recognition, and packaging RNA into protective nanoparticles.
    Another disadvantage is that most RNA vaccines require uninterrupted refrigeration for transportation and storage, which can be a hurdle for vaccine distribution. Research is ongoing to engineer thermostable vaccines.

  • Israel: Over 12,000 people test positive for COVID-19 after receiving Pfizer vaccine

    1:55

    More than 12,400 people have tested positive for coronavirus in Israel after getting inoculated by the Pfizer/BioNtech vaccine, including 69 people who had taken their second jab.

    #Israel #COVID19 #PfizerVaccine

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  • Whats the difference between Covid vaccines? - BBC News

    2:57

    The three Covid-19 vaccines, that have been approved in the UK, are from Pfizer-BioNTech, the University of Oxford and Astra-Zeneca and Moderna.

    The Pfizer, Oxford and Moderna vaccines each require two doses and you are not fully vaccinated until a week after your second shot.

    But there are many differences between them.

    BBC health correspondent Laura Foster looks at how much immunity they give, how they prevent infection and if any are better than the other.

    Video by Mel Lou, Laura Foster, Terry Saunders and Mattea Bubalo

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  • Whats the difference between the major Covid-19 vaccines?

    9:50

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    Covid-19 plagued the world for most of 2020, but at the end of the year, vaccines developed and approved at record speed started to become available for use. With the largest vaccination drive in history under way, what are the differences between the Covid-19 vaccines? How effective are they? What are the potential side effects of some of the vaccines, what are the dosage requirements and how will they get to you? Here’s what you need to know about the Covid-19 vaccine front-runners.


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  • Pfizer vaccine neutralizes Brazil and U.K. variants of Covid-19: Lab study

    5:10

    There's new optimism surrounding Pfizer's coronavirus vaccine's ability to fight against the rapidly spreading new variants. CNBC's Meg Tirrell reports. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    New more contagious variants of the coronavirus are being investigated in the United States, raising questions about whether the Covid vaccines currently in use will provide protection against mutations.

    There are multiple more contagious variants emerging around the globe, in the United Kingdom, South Africa and Brazil. In the U.S., variants from New York City and California have been identified.

    So far, studies suggest that the vaccines currently in use can recognize the emerging variants — but they don’t provide as much protection against these new strains. The variant from South Africa, for example, reduced Pfizer-BioNTech’s antibody protection by two-thirds, according to a February study. Moderna’s neutralizing antibodies dropped six-fold with the South Africa variant.

    (There are several reasons the antibodies generated after receiving a vaccine might recognize a variant but not fight it as well. For instance, antibodies protect you by attaching to each individual spike protein on the surface of the coronavirus, which prevents it from infecting your cell. If a variant produces many times more virus, the antibodies may not be able to attach to all those virus pieces as precisely or efficiently.)

    But boosters and new versions of vaccines that target the variants are already being explored.

    The three vaccines that have been authorized by the Food and Drug Administration for emergency use from Moderna, Pfizer-BioNTech and Johnson & Johnson work in different ways, and therefore have different approaches to handling variants.

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  • South Africa suspends rollout of Oxford-AstraZeneca coronavirus vaccine | DW News

    7:36

    South Africa on Sunday said it would suspend its rollout of the Oxford-AstraZeneca vaccine after initial trials showed disappointing results against the B.1.351 variant of COVID-19 . The country has received 1 million doses of the jab. It had planned to start using it to vaccinate frontline healthcare workers from mid-February. The study, involving around 2,000 people, found the vaccine offered minimal protection against mild and moderate cases of COVID-19. It has not yet been peer-reviewed.

    The government will instead offer vaccines produced by Johnson & Johnson and Pfizer in the coming weeks. This newer strain is more infectious and currently accounts for more than 90% of the COVID-19 cases in the country. South Africa plans to vaccinate at least 67% of its population by the end of the year, or around 40 million people. It has recorded nearly 1.5 million infections and more than 46,000 deaths from the virus.

    Developers of theOxford-AstraZeneca vaccinesay they will have a modified jab ready by the end of this summer. The early results for the AstraZeneca vaccine against the South African variant could have far-reaching implications in the fight against coronavirus on the continent. Many African nationshad been planning to use the AstraZeneca shot owing to its affordability and the fact that it can be kept in ordinary refrigerators. COVAX, an international procurement initiative for poorer countries, has bought the AstraZeneca vaccine in bulk from the Serum Institute of India.

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    #SouthAfrica #AstraZeneca #Coronavirus

  • What’s The Difference Between Pfizer And Moderna COVID-19 Vaccines? | TODAY

    3:41

    NBC’s Tom Costello joins TODAY to talk about the differences between the Pfizer-BioNTech and Moderna COVID-19 vaccines, explaining that the Moderna vaccine does not need to be kept as cold and there is some early evidence that it will protect against transmission.
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    What’s The Difference Between Pfizer And Moderna COVID-19 Vaccines? | TODAY

  • Why you cant compare Covid-19 vaccines

    7:02

    What a vaccine's efficacy rate actually means.

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    In the US, the first two available Covid-19 vaccines were the ones from Pfizer/BioNTech and Moderna. Both vaccines have very high efficacy rates, of around 95%. But the third vaccine introduced in the US, from Johnson & Johnson, has a considerably lower efficacy rate: just 66%.

    Look at those numbers next to each other, and it's natural to conclude that one of them is considerably worse. Why settle for 66% when you can have 95%? But that isn't the right way to understand a vaccine's efficacy rate, or even to understand what a vaccine does. And public health experts say that if you really want to know which vaccine is the best one, efficacy isn't actually the most important number at all.

    Further reading from Vox:

    Why comparing Covid-19 vaccine efficacy numbers can be misleading:

    The vaccine metric that matters more than efficacy:

    The limits of what vaccine efficacy numbers can tell us:

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  • German company BioNTech and Pfizer announce 90% effective coronavirus vaccine | COVID-19 Special

    20:21

    German company BioNTech and its US partner Pfizer announced on Monday that early results from ongoing Phase III trials showed that their vaccine was 90% effective in preventing COVID-19 infections. The statement from the two companies is the first release of successful data from a large-scale trial of coronavirus vaccines. According to their reports, they found no serious safety concern connected with the vaccine. Researchers believe the immunizing effects will not be short-lived. If substantiated, the Pfizer and BioNTech vaccine would be a breakthrough in the fight against the coronavirus pandemic.

    Analysis of the experimental vaccine trials appeared to effectively prevent infection in participants without prior evidence of SARS-CoV-2 infection, the joint statement said. Pfizer cautioned that the initial protection rate may still change as time goes on and made clear that the vaccine was unlikely to be available before the end of the year. Nevertheless, Pfizer's senior vice president of clinical development, Dr. Bill Gruber told the Associated Press: We are very encouraged.

    US President-elect Joe Biden welcomed the promising results from the vaccine trials, but warned that widespread vaccination was still months away. He also urged the US public to continue wearing masks and social distancing. Today’s news is great news, but it doesn't change that fact, Biden said in a statement. Today's announcement promises the chance to change that next year, but the tasks before us now remain the same. US President Donald Trump, celebrated the news and the boost to the stock market as SUCH GREAT NEWS, in a post on Twitter. European stock markets reacted positively to the news with Pfizer's share increasing 6% while BioNTech's US stocks rocketed up by 18%.

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    #Coronavirus #Vaccine #BioNTech

  • How Effective Are Covid Vaccines Like Pfizer, AstraZeneca, Moderna And Others Against Delta Variant

    4:52

    As rising coronavirus infections force some countries to reimpose restrictions, scientists and drugmakers are racing to answer a crucial question: how well do the current vaccines protect against the Delta variant?

    On one point, most observers agree. The leading shots, studies show, still offer strong protection against severe disease and hospitalisation.

    “Real-world effectiveness studies with a number of vaccines show good protection especially against severe disease,” Soumya Swaminathan, chief scientist at the World Health Organization, told the Financial Times. “The most important priority just now is to scale up vaccination coverage in all countries.”

    So called “real-world” analysis of 14,019 cases of the Delta variant in the UK, released by Public Health England in June, found the BioNTech/Pfizer and Oxford/AstraZeneca vaccines were, respectively, 96 per cent and 92 per cent effective against hospitalisation after two doses.

    Late on Thursday, Pfizer reiterated it believed its shot worked against Delta, especially after a potential third booster dose. But it also added it planned to study a variant-targeted inoculation, with trials slated to start as early as next month.

    #DeltaVariant #CovidVaccine #VaccineEfficacy

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  • Can mRNA Vaccines Alter a Person’s DNA?

    2:40

    Dr. Paul Offit explains why it’s not possible for mRNA vaccines to alter a person’s DNA. For information about COVID-19, visit For information about vaccines and vaccine safety, visit

  • Does the COVID-19 Vaccine Change Your DNA?

    38

    Adam Brady, MD, explains why the COVID-19 vaccines do not have the potential for changing our DNA or interacting with it.

  • Canada Recommends Mixing, Matching Of COVID-19 Vaccines- AstraZeneca, Pfizer, Moderna

    2:00

    #COVIDVaccine #VaccineMixing #Coronavirus #COVID19 #RepublicTV

    Based on the study from UK and Spain, Canada, on Tuesday recommended mixing and matching second doses of COVID-19 vaccines. The country is using AstraZeneca, Pfizer, and Moderna and has suggested citizens to combine jabs interchangeably in certain situations. The National Advisory Committee on Immunization (NACI) has extended its support to the decision and updated its guidance to provinces and territories on mixing and matching.

    Canada's Chief Public Health Officer Dr. Theresa Tam also gave a green signal to the process while adding that this is nothing new.

    This is not a new concept, so having a multi-dose series in terms of vaccines given by manufacturers is something that public health has used over time for many other vaccines. When vaccines programs and supplies change this is not an unusual thing to do, said Dr. Theresa Tam to CBC News.

    Dr. Theresa Tam further cited the example of mixing shots for influenza and Hepatitis proving this phenomenon is not new.

    The NACI guidance comes from research conducted in UK, Spain that said mixing and matching shots are safe and effective. The study further recommended first shot of the AstraZeneca vaccine can be followed by either Moderna or Pfizer. Following the recommendations, Canadians have also been advised to take either of the two shots as a second dose after taking first dose of Moderna or Pfizer.

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  • Coronavirus: Digging into the Oxford-AstraZeneca COVID-19 vaccine candidate

    3:02

    A COVID-19 vaccine being developed by the University of Oxford in collaboration with AstraZeneca Plc is producing a similar immune response in both older and younger adults, signaling hopes that the vaccine could be a frontrunner among the numerous vaccines in production and testing.

    Adverse responses were also lower among the elderly, adding more promise to the vaccine's potential as a possible preventative measure against COVID-19.

    The Oxford/AstraZeneca vaccine is expected to be one of the first from big pharma to secure regulatory approval, along with Pfizer and BioNTech’s candidate. Eric Sorensen reports.

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  • COVID-19: Thailand to start administering AstraZeneca vaccine

    2:28

    Thailand will start administering the AstraZeneca jab on Mar 16 after a brief delay over concerns of side effects in Europe.

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