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Johnson and Johnson Vaccine Pause: A Rare Blood Clot Called Cerebral Venous Sinus Thrombosis (CVST)

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  • Johnson and Johnson Vaccine Pause: A Rare Blood Clot Called Cerebral Venous Sinus Thrombosis

    27:01

    Professor Roger Seheult, MD of discusses the association between a rare type of blood clot and the Johnson and Johnson Vaccine, and the decision by the FDA and CDC to recommend pausing the use of the J and J vaccine. Dr. Seheult illustrates cerebral venous sinus thrombosis (CVST), explains the relative risk, treatment, and warning signs of this rare complication (This video was recorded on April 14, 2021).

    Roger Seheult, MD is the co-founder and lead professor at MedCram
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    Interviewer: Kyle Allred, Physician Assistant, Producer, and Co-Founder of MedCram.com


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Overview of FDA & CDC decision to pause Johnson & Johnson vaccine in the U.S. amid rare blood clot cases
    01:54 What is Cerebral Venous Sinus Thrombosis (CVST)?
    03:41 What are the symptoms of CVST, or Cerebral Venous Sinus Thrombosis?
    04:17 Other risk factors for CVST
    04:45 Best tools for medical professionals to make CVST diagnosis
    05:01 Is CVST what we’re seeing with the J&J vaccine, and what’s the actual likelihood of it happening?
    07:05 Why it’s contraindicated for medical professionals to treat these blood clots with heparin products
    07:33 How is this similar and/or different from what’s been reported about the AstraZeneca vaccine and blood clots?
    09:18 Relative risk of CVST from (potentially) J&J vaccine versus other factors
    11:37 What is VAERS? Clearing up some common misunderstandings
    13:25 What to do if you were scheduled to get the Johnson & Johnson vaccine
    14:12 What symptoms to look for if you’ve received the J&J vaccine within the past 2-3 weeks
    15:14 Can clotting from this condition happen in other places in the body besides the brain?
    15:42 Different symptoms of blood clots in the lungs and legs
    15:25 Possible explanation for disproportionate cases of post-J&J vaccine thrombosis in young women
    18:03 Should people proceed as normal with receiving mRNA COVID-19 vaccines (such as Pfizer-BioNTech and Moderna)?
    19:36 Different perspectives on decision to pause J&J vaccination amid vaccine hesitancy
    23:11 Advice for people still on the fence about receiving a COVID-19 vaccine
    24:43 How to care for yourself and others to prevent further lockdown and COVID-19 transmission


    LINKS / REFERENCES:

    Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination | (New England Journal of Medicine)

    Joint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine | (FDA)

    Vaccine Adverse Event Reporting System |

    Worldometer |

    Newsweek |

    Nate Silver’s Twitter Page |

    All coronavirus updates are at MedCram.com (including more discussion on Johnson & Johnson Vaccine, COVID variants, COVID mutations, COVID 19 Vaccine, Pfizer Vaccine, Moderna Vaccine, coronavirus variant, Cerebral Venous Sinus Thrombosis, CVST, COVID vaccine, vaccine uptake, and more).


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  • Johnson & Johnson vaccine blood clots: What is cerebral venous sinus thrombosis ?

    1:01

    The U.S. has paused the use of Johnson & Johnson’s one-shot coronavirus vaccine over concerns about bloods clots.
    In a joint statement on April 13, the Centers for Disease Control and Prevention and the Food and Drug Administration said they were recommending a “pause” until an investigation can be completed. The FDA and CDC will examine possible links between cerebral venous sinus thrombosis (CVST) and the vaccine to determine whether the shots should still be eligible for all adults or limited to certain groups.

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  • Cerebral Venous Sinus Thrombosis, CVST, Animation

    3:44

    CVST is a type of brain stroke caused by blood clots in a vein. This rare blood clot disorder prompted the current pause of Johnson & Johnson (J&J) COVID-19 vaccine, as well as Astrazeneca vaccine.
    Pathophysiology, signs and symptoms, risk factors, diagnosis, treatment and prognosis. Other names: Cerebral vein thrombosis, Cerebral sinovenous thrombosis, Cerebral venous thrombosis (CVT), Cerebral venous and sinus thrombosis, Cerebral venous sinus thrombosis (CVST), Cerebral sinovenous thrombosis (CSVT), Cerebral vein and dural sinus thrombosis, Sinus and cerebral vein thrombosis.
    This video is available for instant download licensing here:
    ©Alila Medical Media. All rights reserved.
    Voice by : Marty Henne
    Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
    All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
    Cerebral venous sinus thrombosis, CVST, occurs when a blood clot forms and blocks a vein in the brain.
    Blood is transported to the brain in arteries. After delivering oxygen and nutrients, it leaves in veins. Small veins of the brain are called cerebral veins. They drain into large veins, called sinus veins, or venous sinuses. Sinus veins empty into jugular veins, which carry the blood back to the heart.
    A blockage in a vein causes the blood to back up in the brain, increasing pressure, causing headache, which is often severe. The increased pressure may damage the surrounding brain tissue, producing stroke symptoms such as blurred vision, confusion, loss of consciousness, loss of movement control, seizure or coma. The engorged blood vessel may also rupture, bleeding into the brain, a condition known as “venous hemorrhagic stroke”.
    Unlike arterial thrombosis that causes the typical brain stroke, venous thrombosis usually develops slowly. This is due to the slow growth of blood clots in veins, and the ability of the venous system to form new vessels to bypass an obstruction, maintaining more or less normal flow at first. In most cases, symptoms develop gradually, over days, weeks or even months, but sudden onset may also occur.
    CVST is a rare type of stroke that can affect all age groups, including infants. Risks factors include: having inherited blood disorders, systemic conditions, cancers; use of certain medications, and some infections. Women of reproductive age are more at risk due to pregnancy and use of birth control pills. Infants with difficult birth, or whose mothers had certain infections, are also more vulnerable.
    CVST is often misdiagnosed due to its rarity, wide spectrum of symptoms, and the fact that symptoms can appear suddenly or gradually. The standard MRI or CT scans used to detect stroke are often normal in CVST. To diagnose CVST, the veins must be specifically examined in a procedure called magnetic resonance venography. CVST must be suspected in patients of any age who have severe headache that doesn’t go away, and any risk factors for clotting disorders.
    Timely diagnosis and prompt treatments are essential for survival. Immediate treatment includes blood thinners, typically intravenous heparin, or subcutaneous low-molecular-weight heparin. The goal is to prevent the enlargement of existing clots and formation of new clots, while letting the body’s own system dissolves the existing clots slowly, typically over weeks or months. However, patients who have bleeding must be monitored closely to ensure it does not worsen. If the patient deteriorates despite heparin, catheter-directed procedures to breakdown blood clots may be considered.
    Once the patient is out of danger, an oral anticoagulant such as warfarin is typically given for 3 to 6 months, although patients with known clotting disorders may need to take warfarin for life. About 3 in 4 patients fully recover, but it may take some time to get back to normal.

  • CDC Panel Recommends Lifting Pause On J&J Vaccine After Rare Blood Clots | NBC News NOW

    5:53

    An advisory committee to the CDC recommended that the Johnson & Johnson Covid-19 vaccine resume distribution after rare blood clots were reported.
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    CDC Panel Recommends Lifting Pause On J&J Vaccine After Rare Blood Clots | NBC News NOW

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  • Fauci explains Johnson & Johnson vaccine pause over blood clots

    3:31

    During a Tuesday White House press briefing, Dr. Anthony Fauci explained the Johnson & Johnson COVID-19 vaccine pause after serious blood clots were reported in six recipients.

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  • Cerebral Venous Sinus Thrombosis: A Patient Primer

    13:31

    This month, we welcome Dr. Gregory Piazza for an overview on cerebral venous sinus thrombosis (CVST), a rare condition that has recently been associated with the Johnson & Johnson COVID-19 vaccine. Dr. Piazza is an Associate Professor of Medicine at Harvard Medical School, Section Head of Vascular Medicine at Brigham and Women's Hospital, and a member of NATF’s Board of Directors.

  • x
  • Johnson & Johnson vaccine: Other medicines, habits tied to blood clotting | KVUE

    1:50

    The Johnson & Johnson vaccine was specifically tied to blood clots called cerebral venous sinus thrombosis, which can affect the brain. But blood clots have been tied to other medications and habits for years.

    RELATED:

    KVUE is Austin's ABC affiliate station and has been delivering local news for Central Texans since 1971. Today it is owned by TEGNA, Inc., which reaches approximately one-third of all television households in America.

  • Blood clots and COVID vaccines

    8:05

    What do we know so far about the link between the Astra-Zeneca and Janssen (Johnson & Johnson) COVID vaccines and a rare type of blood clot combined with low platelets (cerebral venous sinus thrombosis with thrombocytopenia)?

    References:

    CDC, Johnson & Johnson/Janssen COVID-19 Vaccine and Cerebral Venous Sinus Thrombosis with Thrombocytopenia – Update for Clinicians on Early Detection and Treatment:

    Boonyawat K, Chantrathammachart P, Numthayaj P, Nanthatani N, Physanti S, Phuphuakrat A, Niparuck P, Angchaisuksiri P. Incidence of thromboembolism in patients with COVID-19: a systematic review and meta-analysis. Thrombosis Journal 2020; 18:34

    Cheng YJ, Liu ZH, Yao FJ, Zeng WT, Zheng DD, Dong YG, Wu SH. Current and former smoking and risk for venous thromboembolism: a systematic review and meta-analysis. PLoS Med 2013;10(9):e1001515

    Devis P, Knuttinen MG. Deep venous thrombosis in pregnancy: incidence, pathogenesis and endovascular management. Cardiovasc Diagn Ther 2017;7(Suppl 3):S309-S319.

    McCartney M. Medicine: before COVID-19, and after. Lancet 2020;395:1248-49

  • CDC Webinar J&J/Janssen COVID19 Vaccine CVST Thrombosis w/Thrombocytopenia

    57:27

    This COCA Call will present the latest evidence on cerebral venous sinus thrombosis (CVST) with thrombocytopenia associated with the administration of the Johnson & Johnson/Janssen COVID-19 vaccine. Speakers will discuss what is known about CVST, the importance of early detection, and updated vaccine recommendations.

    This video can also be viewed at

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  • Johnson & Johnson COVID-19 vaccine pause: What you need to know about blood clots

    2:16

    Federal health officials are recommending a pause on the use of the Johnson & Johnson COVID-19 vaccine after six cases of a rare type of blood clotting following vaccination were reported in the United States.

    The U.S. Food and Drug Administration and U.S. Centers for Disease Control and Prevention said in a joint statement Tuesday that the pause of the single-dose vaccine is out of an abundance of caution while the agencies investigate the cases.

    Dr. Mike Cirigliano says the pause on the Johnson & Johnson vaccine is a precaution and suggests that if you received the single-dose and are noticing changes, such as a swollen leg, you should see your health care provider.

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  • Johnson & Johnson vaccine review follows blood clot cases | Coronavirus Vaccine |Latest English News

    1:55

    European drug regulators are undertaking review of rare blood clots in four people in the United States of America who have received Johnson & Johnson COVID-19 vaccine.

    #J&J #CoronavirusVaccine #EnglishNews

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  • J&J respond to six cases of blood clots after receiving its Covid vaccine

    51

    The Food and Drug Administration said Tuesday it is asking states to temporarily halt using Johnson & Johnson’s Covid-19 vaccine after six people in the U.S. developed a rare blood clotting disorder. J&J said in a statement that “no clear causal relationship” has been identified between the blood clots and the vaccine, adding it is working closely with regulators to assess the data. CNBC's Meg Tirrell reports. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    The Food and Drug Administration asked states on Tuesday to temporarily halt using Johnson & Johnson’s Covid-19 vaccine “out of an abundance of caution” after six women in the U.S. developed a rare blood-clotting disorder that left one woman dead and another in critical condition.

    “Right now, these adverse events appear to be extremely rare,” the FDA said in a joint statement with the Centers for Disease Control and Prevention. “COVID-19 vaccine safety is a top priority for the federal government, and we take all reports of health problems following COVID-19 vaccination very seriously.”

    All six cases occurred in women ages 18 to 48, with symptoms developing six to 13 days after they received the shot. Doctors typically treat that type of blood clot with heparin, but health regulators noted that could be dangerous in this case and recommended a different treatment.

    J&J said in a statement that “no clear causal relationship” has been identified between the blood clots and the vaccine, adding it is working closely with regulators to assess the data.

    People who got the J&J vaccine more than a month ago are at very low risk for developing the blood clots, Dr. Anne Schuchat, the principal deputy director of the CDC, told reporters on a conference call Tuesday.

    “For people who recently got the vaccine within the last couple weeks, they should be aware to look for any symptoms,” she said. “If you’ve received the vaccine and developed severe headaches, abdominal pain, leg pain or shortness of breathe you should contact your healthcare provider and seek medical treatment.”

    The blood clotting generally occurs about a week after vaccination, but not more than three weeks after, with a median timeframe of 9 days, Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said on the call.

    “We know that for these vaccines, that for the first several days after vaccination, there are flu-like symptoms that can include headache,” he said, adding that those are likely common adverse events. “It would be more likely if someone presented to an emergency room with very severe headache or blood clots, that a history of vaccination be elicited” and a plan of care put in place. If the patient also has low platelets, doctors should consider that it may be related to the vaccine, he said.

    Shares of J&J fell by almost 3% in intraday trading.

    The FDA said the pause is expected to last a matter of days.

    The CDC will convene a meeting of the Advisory Committee on Immunization Practices on Wednesday to further review the cases, federal health regulators said Tuesday. The FDA is also investigating the cases.

    Last week, Europe’s medicines regulator said it found a possible link between the coronavirus vaccine developed by AstraZeneca and the University of Oxford and rare blood-clotting issues. AstraZeneca has not received authorization for use in the U.S.

    Emer Cooke, executive director of the European Medicines Agency, said in a televised news conference last week that unusual blood clotting with low blood platelets would be added as a “very rare” side effect to the AstraZeneca vaccine’s product information, along with a slew of other possible adverse reactions.

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  • Officials Scramble To Calm Skeptics After Blood Clots Associated With J&J Vaccine | Sunday TODAY

    4:59

    The CDC and FDA recommended a pause in the use of the Johnson & Johnson COVID-19 vaccine after six cases of a “rare and severe” blood clotting were reported among the nearly 7 million doses administered in the United States. Public health officials scrambled to defend the move as concerns grew that it would make more Americans skeptical about getting a vaccine. NBC News medical correspondent Dr. John Torres has this week’s Sunday Focus.
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    Officials Scramble To Calm Skeptics After Blood Clots Associated With J&J Vaccine | Sunday TODAY

  • Investigation into rare cases of blood clots with the J&J vaccine | GMA

    3:41

    Director of the Maine CDC, Dr. Nirav Shah, discusses the advantages of the J&J shot, not needing ultra-cold storage and how the dosage drop-off will affect the vaccination push.

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  • Clotting cases are a devastating blow to J&J vaccine: Dr. Kavita Patel

    4:14

    The Food and Drug Administration said Tuesday it is asking states to temporarily halt using Johnson & Johnson’s Covid-19 vaccine after six people in the U.S. developed a rare blood clotting disorder. Dr. Kavita Patel, fellow at the Brookings Institution, joined Squawk Box to discuss the news. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    The Food and Drug Administration asked states on Tuesday to temporarily halt using Johnson & Johnson’s Covid-19 vaccine “out of an abundance of caution” after six women in the U.S. developed a rare blood-clotting disorder that left one woman dead and another in critical condition.

    “Right now, these adverse events appear to be extremely rare,” the FDA said in a joint statement with the Centers for Disease Control and Prevention. “COVID-19 vaccine safety is a top priority for the federal government, and we take all reports of health problems following COVID-19 vaccination very seriously.”

    All six cases occurred in women ages 18 to 48, with symptoms developing six to 13 days after they received the shot. Doctors typically treat that type of blood clot with heparin, but health regulators noted that could be dangerous in this case and recommended a different treatment.

    J&J said in a statement that “no clear causal relationship” has been identified between the blood clots and the vaccine, adding it is working closely with regulators to assess the data.

    People who got the J&J vaccine more than a month ago are at very low risk for developing the blood clots, Dr. Anne Schuchat, the principal deputy director of the CDC, told reporters on a conference call Tuesday.

    “For people who recently got the vaccine within the last couple weeks, they should be aware to look for any symptoms,” she said. “If you’ve received the vaccine and developed severe headaches, abdominal pain, leg pain or shortness of breathe you should contact your healthcare provider and seek medical treatment.”

    The blood clotting generally occurs about a week after vaccination, but not more than three weeks after, with a median timeframe of 9 days, Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said on the call.

    “We know that for these vaccines, that for the first several days after vaccination, there are flu-like symptoms that can include headache,” he said, adding that those are likely common adverse events. “It would be more likely if someone presented to an emergency room with very severe headache or blood clots, that a history of vaccination be elicited” and a plan of care put in place. If the patient also has low platelets, doctors should consider that it may be related to the vaccine, he said.

    Shares of J&J fell by almost 3% in intraday trading.

    The FDA said the pause is expected to last a matter of days.

    The CDC will convene a meeting of the Advisory Committee on Immunization Practices on Wednesday to further review the cases, federal health regulators said Tuesday. The FDA is also investigating the cases.

    Last week, Europe’s medicines regulator said it found a possible link between the coronavirus vaccine developed by AstraZeneca and the University of Oxford and rare blood-clotting issues. AstraZeneca has not received authorization for use in the U.S.

    Emer Cooke, executive director of the European Medicines Agency, said in a televised news conference last week that unusual blood clotting with low blood platelets would be added as a “very rare” side effect to the AstraZeneca vaccine’s product information, along with a slew of other possible adverse reactions.

    Isaac Bogoch, an infectious disease specialist who has sat on several drug data and safety monitoring boards, said J&J and AstraZeneca use the same platform for their vaccines. The J&J and AstraZeneca vaccines use an adenovirus, a common type of virus that typically causes mild cold symptoms.

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  • The J&J Vaccine and Blood Clots: What Do We Know & What Should We Do?

    1:5:54

    In this UCSF Department of Medicine Covid-19 Grand Rounds, we will discuss the pause in the use of the Johnson & Johnson vaccine after reports of rare and dangerous blood clots. Dr. John Moore, an international expert on virology and immunology, will review what we currently know about this side effect. He’ll also discuss the mechanisms of the various vaccines, as well as their efficacy and side effects. UCSF hematology expert Dr. Andrew Leavitt will discuss what is known about the syndrome of vaccine-induced thrombotic thrombocytopenia, including how to recognize and treat the disorder. The session is moderated by UCSF Department of Medicine Chair Bob Wachter.

    Program
    Bob Wachter: Introduction
    00:04:25-00:43:47 – Conversation with John Moore (Professor of Microbiology and Immunology, Weill Cornell Medicine, Cornell University
    00:43:47¬¬-01:00:00 – Discussion about Thrombotic Thrombocytopenia: Andrew Leavitt (UCSF Professor of Laboratory Medicine and Medicine; Director of UCSF's Program for Noncancerous Blood Disorders; and Co-Director of the UCSF Hemophilia Treatment Center)
    01:00:00-01:05:26 – Q&A and Conversation with Andrew Leavitt
    Bob Wachter: Closing

    See previous Covid-19 Medical Grand Rounds:
    • April 8: The Fourth Wave, and “Is it Safe to…?”
    • March 25: The State of the Pandemic, Therapeutics, and Emerging Data on Variants
    • March 11: Covid at One Year: Looking Back and Looking Ahead
    • February 18: The 23rd Annual Reza Gandjei Memorial Lecture: A Conversation with Atul Gawande

    See all UCSF Covid-19 grand rounds, which have been viewed over 1.78M times, here:

  • CDC, FDA lift recommended pause on J&J vaccine

    3:05

    Meg Tirrell joins 'The News with Shepard Smith' to report the CDC and FDA have lifted the recommended pause on the use of the J&J vaccine. The committee found benefits of the vaccine outweighed the risks of the rare blood clots. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    U.S. health regulators on Friday lifted a recommended pause on the use of Johnson & Johnson’s Covid-19 vaccine, giving state and local officials backing to distribute the doses, which are seen as critical in getting lifesaving shots to hard-to-reach communities.

    The announcement from the Centers for Disease Control and Prevention and the Food and Drug Administration comes after the CDC’s Advisory Committee on Immunization Practices, known as ACIP, recommended earlier Friday for the continued use of the J&J vaccine, saying the benefits of the shot outweighed the risk. The committee is an outside panel of experts that advises the CDC.

    Members of the advisory panel didn’t recommend U.S. regulators restrict the use of the J&J vaccine based on age or gender, but they did propose that the Food and Drug Administration consider adding a warning label for women under the age of 50.

    In a statement late Friday, the FDA and CDC said they were confident that the vaccine is safe and effective in preventing Covid-19, adding the risk of the blood clots is “very low.”

    “Safety is our top priority,” Acting FDA Commissioner Dr. Janet Woodcock said in a statement. “This pause was an example of our extensive safety monitoring working as they were designed to work—identifying even these small number of cases.”

    “We’ve lifted the pause based on the FDA and CDC’s review of all available data and in consultation with medical experts and based on recommendations from the CDC’s Advisory Committee on Immunization Practices,” Woodcock said. “We have concluded that the known and potential benefits of the Janssen COVID-19 Vaccine outweigh its known and potential risks in individuals 18 years of age and older.”

    During a press conference on the announcement, Woodcock said health-care providers should review revised fact sheets from the FDA about the vaccine, which includes details about rare blood clots. People who have questions about the vaccine should discuss with a health-care provider, she said.

    J&J’s Covid-19 vaccine, like Pfizer’s and Moderna’s shots, received an emergency use authorization from the FDA to start distributing the doses across the U.S. An EUA grants conditional clearance based on two months of safety data, pending another submission for full approval, which usually requires at least six months of data.

    On April 13, the FDA and CDC asked states to temporarily halt using J&J’s vaccine “out of an abundance of caution” following reports that six women, ages 18 to 48, developed cerebral venous sinus thrombosis in combination with low blood platelets. CVST occurs when a blood clot forms in the brain’s venous sinuses. It can prevent blood from draining out of the brain and can eventually cause a hemorrhage and other brain damage.

    Within hours of the warning from U.S. regulators, more than a dozen states, along with some national pharmacies, halted inoculations with J&J’s vaccine. Some locations replaced the J&J shots for scheduled appointments with either the Pfizer or Moderna vaccine.

    The U.S. government was expected to lift the recommended pause shortly after the favorable vote from the committee.

    Prior to Friday’s vote, the committee debated whether to recommend against the use of J&J’s vaccine or endorse it with U.S. regulators enforcing a warning label. The committee also considered limiting the vaccine’s use based on age or other risk factors.

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  • What is cerebral venous sinus thrombosis ?

    3:17

    Cerebral venous sinus thrombosis (CVST) has been prominent in the news recently. Our medical director explains CVST using the BioDigital Human 3D visualizations.

    *** BioDigital is happy to share helpful health information, but we do not offer medical advice. For medical advice, please contact your healthcare provider directly. ***

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  • Blood clot risks associated with AstraZeneca and Janssen COVID-19 vaccines and weighing the benefits

    7:52

    Learn about potential risks and side effects of the Oxford/AstraZeneca and Janssen (Johnson & Johnson) vaccines, including blood clots and Vaccine-Induced Immune Thrombocytopenia (VIIT). Experts discuss the impact of blood thinner medications and having a low count of blood platelets, which as some of the factors to consider when balancing the risks and benefits.

    Speaker: Dr. Eric Benchimol (MD, PhD, FRCPC), Professor, Pediatric Gastroenterologist, Department of Paediatrics, The Hospital for Sick Children (SickKids) and University of Toronto, Division of Gastroenterology, Hepatology and Nutrition, SickKids, NASPGHAN Canadian Councilor, Chair of the Scientific and Medical Advisory Council, Crohn's and Colitis Canada | Twitter: @ericbenchimol

    For more information please visit,

  • FDA calls to pause Johnson & Johnson vaccines over rare blood clots: CNBC After Hours

    11:02

    CNBC.com's Pippa Stevens brings you the day's top business news headlines. On today's show, Meg Tirrell explains why the FDA and CDC called to halt the administration of Johnson & Johnson vaccines after six women developed a rare blood clot disorder. Plus, Kate Rogers explores why restaurants are having trouble rehiring workers as diners return.

    00:00 -- Intro
    0:37 -- S&P 500 climbs to another record close
    1:25 -- FDA and CDC call for pausing use of Johnson & Johnson vaccine
    4:28 -- CNBC Soundcheck
    6:06 -- Restaurant worker shortage
    8:29 -- Numbers round

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  • U.S. calls for pause of J&J vaccine due to rare blood clot risk | KVUE

    2:36

    The CDC and FDA are recommending a pause of the Johnson & Johnson vaccine to investigate extremely rare reports of a specific kind of blood clot. Six out of the more than 6.8 million who have received the vaccine in the U.S. developed clots.

    STORY:

    KVUE is Austin's ABC affiliate station and has been delivering local news for Central Texans since 1971. Today it is owned by TEGNA, Inc., which reaches approximately one-third of all television households in America.

  • FDA Pauses Johnson & Johnson Vaccine Rollout After Cases Of Rare Blood Clots | NBC News NOW

    5:07

    The FDA has announced a pause in distribution of the Johnson & Johnson Covid-19 vaccine as six women developed rare blood clots after receiving the shot. In a statement, Johnson & Johnson said “no clear causal relationship has been established” between rare blood clots and the vaccine.
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    FDA Pauses Johnson & Johnson Vaccine Rollout After Cases Of Rare Blood Clots | NBC News NOW

  • J&J vaccine paused due to rare blood-clotting issues

    10:09

    The FDA is asking states to temporarily halt using J&J's Covid-19 vaccine after six people in the U.S. developed a rare blood-clotting disorder. The FDA said the recommendation is out of an abundance of caution. The cases occurred in women ages 18 to 48, with symptoms developing six to 13 days after they received the shot. Here's what experts are saying. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

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  • Jacksonville cardiologist: Blood clots reported after J&J vaccine ‘very rare’

    3:03

    The type of blood clot seen after these vaccines does not happen often. News4Jax reporter Erik Avanier spoke with one of the area's leading authorities on Coronavirus vaccines.

  • J&J covid vaccine paused due to rare blood clots

    3:31

    They said nearly 7 million doses had already been administered.

  • U.S. calls for pause on Johnson & Johnson vaccine over rare blood clots

    4:00

    Federal health officials have asked states to pause administering the Johnson & Johnson vaccine in the U.S. after six women developed a rare blood clot. Jericka Duncan shares the latest.

    CBS Evening News with Norah O'Donnell delivers the latest news and original reporting, and goes beyond the headlines with context and depth. Catch the CBS Evening News every weekday night at 6:30 p.m. ET on the CBS Television Network and at 10 p.m. ET on CBSN.

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  • US recommends pause for Johnson & Johnson COVID vaccines over rare clot reports

    2:37

    The U.S. is recommending a “pause” of the single-dose Johnson & Johnson COVID-19 vaccine to investigate reports of potentially dangerous blood clots.

    In a joint statement Tuesday, the Centers for Disease Control and Prevention and the Food and Drug Administration said they were investigating clots in six women that occurred 6 to 13 days after vaccination. The clots were observed in the sinuses of the brain along with reduced platelet counts — making the usual treatment for blood clots, the blood thinner heparin, potentially “dangerous.”

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  • FDA And CDC Recommend J&J Vaccine Pause, Say Blood Clots Appear To Be Extremely Rare | NBC News NOW

    3:23

    Leaders from the FDA and CDC announced in a press call that the recommendation is being made “out of an abundance of caution” after learning of six cases of “a rare and severe type of blood clot” after vaccination.
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    FDA And CDC Recommend J&J Vaccine Pause, Say Blood Clots Appear To Be Extremely Rare | NBC News NOW

  • Jacksonville cardiologist: Blood clots reported after J&J vaccine ‘very rare’

    2:17

    VIDEO: The U.S. recommended a pause in using the single-dose Johnson & Johnson COVID-19 vaccine to investigate rare blood clots that occurred in six women 6 to 13 days after vaccination.

  • Johnson & Johnson: U.S. regulators call for vaccine pause after blood clot reports

    1:04

    The CDC and FDA have issued a joint statement recommending a pause in the use of the Johnson & Johnson COVID-19 vaccine in the United States. The agencies say they are reviewing six reported cases of a rare type of blood clot in people who have received the vaccine. Nearly 7 million doses have already been administered in the country.

    Each weekday morning, CBS This Morning co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs.

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  • Dr. George Williams with UT Health explains CVST: Cerebral Venous Sinus Thrombosis

    47

    CVST is the type of blood clot that's been associated with the Johnson and Johnson COVID vaccine.

  • CDC extends review of Johnson & Johnson vaccine amid pause over rare blood clot cases

    3:19

    An emergency meeting of a Centers for Disease Control and Prevention advisory committee was held to discuss the extremely rare blood clots possibly associated with the Johnson and Johnson COVID-19 vaccine. The meeting ended without a decision on when the shots can be given again. CBS News' Laura Podesta joined CBSN AM with the latest.

    CBSN is CBS News’ 24/7 digital streaming news service featuring live, anchored coverage available for free across all platforms. Launched in November 2014, the service is a premier destination for breaking news and original storytelling from the deep bench of CBS News correspondents and reporters. CBSN features the top stories of the day as well as deep dives into key issues facing the nation and the world. CBSN has also expanded to launch local news streaming services in major markets across the country. CBSN is currently available on CBSNews.com and the CBS News app across more than 20 platforms, as well as the Paramount+ subscription service.

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  • U.S. pauses J&J COVID-19 vaccine over rare blood clots

    1:34

    U.S. federal health agencies on Tuesday recommended pausing the use of Johnson & Johnson’s COVID-19 vaccine after six women under 50 given the shot developed rare blood clots, dealing a fresh setback to efforts to tackle the pandemic.

    #COVID #Vaccine #News #Reuters

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  • COVID 19 Johnson and Johnson Vaccine pause due to Blood Clots. Whats the Deal?

    5:16

    Video Dated April 13th 2021
    UPDATE: Since the demographic affected by this is women 18-55 years old, in that particular group, the incidence is more than 1 in a million and more like 1 in 250k. Which is indeed higher then the background risk of this disease in the general population.


    Today the FDA paused administration of the Johnson & Johnson COVID-19 Vaccine due to concerns of a particular type of blood clot called Cerebral Venous Sinus Thrombosis, or CVST. Is this a real concern? What is the risk of getting this? How common is this diagnosis? And should we be worried? These are all good questions, and I probably know what you already know, but here I try to put things in perspective...
    #Covid #SarsCov2 #Vaccines

  • U.S. Recommends Pause for Johnson & Johnson Vaccine Over Blood Clot Reports

    8:00

    U.S. health officials called for an immediate pause in use of Johnson & Johnson’s single-dose Covid-19 vaccine after six women who received it developed a rare and severe form of blood clotting.

    The decision comes at a crucial juncture in the U.S. vaccination effort, which has been gaining speed in recent weeks at the same time that a worsening outbreak driven by coronavirus variants is gripping the upper Midwest. And it is likely to heighten worry about vaccines around the world after similar issues caused delays in distribution of AstraZeneca Plc’s shot.

    A type of brain blood clot called cerebral venous sinus thrombosis was seen with low levels of blood platelets in the women, who were all between the ages of 18 and 48, the U.S. Centers for Disease Control and Prevention and Food and Drug Administration said on Tuesday in a joint statement.

    “We are recommending a pause in the use of this vaccine out of an abundance of caution,” the CDC and the FDA said in the statement. “This is important, in part, to ensure that the health care provider community is aware of the potential for these adverse events and can plan for proper recognition and management due to the unique treatment required with this type of blood clot.”

    More than 6.8 million doses of the J&J vaccine have been administered in the U.S. through Monday, the agencies said.

    The Biden administration has been seeking to accelerate vaccinations in recent weeks as new coronavirus variants heighten the risk that the pandemic could drag on. Officials expect 100 million doses of J&J’s vaccine to help cover all adults near the end of May.

    The prospect that the pause could disrupt the U.S. economic recovery weighed on financial markets on Tuesday, with futures trading indicating that the stock market was likely to open lower. Contracts tied to the S&P 500 were down roughly 0.23%.

    J&J representatives didn’t immediately respond to a request for comment. The shares fell 3% in premarket U.S. trading.

    covid-vaccine-tracker-global-distribution-us-supply-chain-inline
    The decision could increase vaccine hesitancy, which is seen as a significant obstacle for health policy makers as they attempt to broaden immunizations. The J&J shot has been popular due to its single dose -- vaccines made by Pfizer Inc.-BioNTech SE and Moderna Inc. require two doses spaced several weeks apart.

    Many of the J&J doses in the U.S. have been targeted to harder-to-reach populations through the federal government’s distribution program that targets pharmacies, federally qualified health centers and other locations.

    The CDC will convene a meeting Wednesday of its Advisory Committee on Immunization Practices to review the cases and assess their potential significance. The FDA will review the CDC assessment as it also investigates these cases, according to the statement.

    The recommended pause may also further complicate the global vaccination push, coming just weeks after a vaccine relying on a similar approach and developed by AstraZeneca and the University of Oxford raised similar concerns in Europe. Clotting fears have prompted many countries to impose age restrictions on use of the Astra vaccine, which was co-developed with the University of Oxford.

    J&J has recently begun shipments to the European Union. The bloc’s drugs regulator, the European Medicines Agency, didn’t immediately respond to a request for comment.

    The EMA has previously said that it is assessing blood clots in people who received the J&J vaccine, after four serious cases of unusual clots accompanied by low blood platelets, one of which was fatal, emerged.

    On Friday afternoon, FDA spokesperson Abby Capobianco said in an emailed statement that the agency hadn’t found a causal relationship with between the J&J vaccine and the six cases of thromboembolic events, and was continuing its assessment of the cases.

    “Our analysis of the data will inform the potential need for regulatory action,” she said.

    Asked Monday if further analysis had determined a casual relationship, the FDA declined to comment.

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  • J&J Vaccine: Six Cases of Rare Blood Clot Disorder Found in U.S.

    1:24

    U.S. health officials called for an immediate pause in use of Johnson & Johnson’s single-dose Covid-19 vaccine after six women who received it developed a rare and severe form of blood clotting.

    The decision comes at a crucial juncture in the U.S. vaccination effort, which has been gaining speed in recent weeks at the same time that a worsening outbreak driven by coronavirus variants is gripping the upper Midwest. And it is likely to heighten worry about vaccines around the world after similar issues caused delays in distribution of AstraZeneca Plc’s shot.

    A type of brain blood clot called cerebral venous sinus thrombosis was seen with low levels of blood platelets in the women, who were all between the ages of 18 and 48, the U.S. Centers for Disease Control and Prevention and Food and Drug Administration said on Tuesday in a joint statement.

    “We are recommending a pause in the use of this vaccine out of an abundance of caution,” the CDC and the FDA said in the statement. “This is important, in part, to ensure that the health care provider community is aware of the potential for these adverse events and can plan for proper recognition and management due to the unique treatment required with this type of blood clot.”

    More than 6.8 million doses of the J&J vaccine have been administered in the U.S. through Monday, the agencies said.

    The Biden administration has been seeking to accelerate vaccinations in recent weeks as new coronavirus variants heighten the risk that the pandemic could drag on. Officials expect 100 million doses of J&J’s vaccine to help cover all adults near the end of May.

    The prospect that the pause could disrupt the U.S. economic recovery weighed on financial markets on Tuesday, with futures trading indicating that the stock market was likely to open lower. Contracts tied to the S&P 500 were down roughly 0.23%.

    J&J representatives didn’t immediately respond to a request for comment. The shares fell 3% in premarket U.S. trading.

    The decision could increase vaccine hesitancy, which is seen as a significant obstacle for health policy makers as they attempt to broaden immunizations. The J&J shot has been popular due to its single dose -- vaccines made by Pfizer Inc.-BioNTech SE and Moderna Inc. require two doses spaced several weeks apart.

    Many of the J&J doses in the U.S. have been targeted to harder-to-reach populations through the federal government’s distribution program that targets pharmacies, federally qualified health centers and other locations.

    The CDC will convene a meeting Wednesday of its Advisory Committee on Immunization Practices to review the cases and assess their potential significance. The FDA will review the CDC assessment as it also investigates these cases, according to the statement.

    The recommended pause may also further complicate the global vaccination push, coming just weeks after a vaccine relying on a similar approach and developed by AstraZeneca and the University of Oxford raised similar concerns in Europe. Clotting fears have prompted many countries to impose age restrictions on use of the Astra vaccine, which was co-developed with the University of Oxford.

    J&J has recently begun shipments to the European Union. The bloc’s drugs regulator, the European Medicines Agency, didn’t immediately respond to a request for comment.

    The EMA has previously said that it is assessing blood clots in people who received the J&J vaccine, after four serious cases of unusual clots accompanied by low blood platelets, one of which was fatal, emerged.

    On Friday afternoon, FDA spokesperson Abby Capobianco said in an emailed statement that the agency hadn’t found a causal relationship with between the J&J vaccine and the six cases of thromboembolic events, and was continuing its assessment of the cases.

    “Our analysis of the data will inform the potential need for regulatory action,” she said.

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  • BJC neurologist spreads word about blood clots after Johnson & Johnson COVID vaccine put on pause

    2:08

    With the Johnson and Johnson COVID vaccine on pause as the CDC investigates a handful of rare blood clots in vaccine takers, more attention is being focused on strokes.

  • FDA and CDC call for pause on Johnson & Johnson COVID-19 vaccine after blood clot reports | ABC7

    1:51

    The U.S. is recommending a pause in administration of the single-dose Johnson & Johnson COVID-19 vaccine to investigate reports of potentially dangerous blood clots.

  • FDA And CDC Recommend Pausing J&J Covid Vaccinations After ‘Rare’ Blood Clots | NBC Nightly News

    2:43

    The health agencies announced the recommendation “out of an abundance of caution.” Authorities say 6 women out of 7 million people who have received the vaccine developed rare and severe blood clotting.
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    FDA And CDC Recommend Pausing J&J Covid Vaccinations After ‘Rare’ Blood Clots | NBC Nightly News

  • US Regulators Recommend Pause On J&J Vaccine Over Rare Blood Clots

    33

    The United States has recommended pausing the use of Johnson&Johnson's vaccine against the coronavirus after the discovery of a rare and severe type of blood clot in six people. Today FDA and @CDCgov issued a statement regarding the Johnson & Johnson #COVID19 vaccine. We are recommending a pause in the use of this vaccine out of an abundance of caution, US drug regulator Food and Drug Administration tweeted.

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  • US calls for pause on Johnson & Johnson vaccine over blood clot reports

    2:17

    US federal authorities have urged health officials to hold off on using the Johnson & Johnson vaccine - because six people out of the 6.8 million who received it have developed blood clots, and one died.
    The Johnson & Johnson vaccine is administered in a single dose, is cheaper than other vaccines, and can be kept at regular refrigeration temperatures.
    The delay is expected to last just days, but what they uncover about this could have a huge impact on the many countries counting on this vaccine to get them past the pandemic.

    Al Jazeera’s Patty Culhane reports from Silver Spring in the US state of Maryland.

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    #COVID19Vaccine #Johnson&Johnson #VaccineBloodClots

  • U.S. recommends pause for Johnson & Johnson  vaccine over clots

    2:33

    U.S. health officials urged a pause in the use of Johnson & Johnson's COVID-19 vaccine after serious blood clots were reported in six recipients nationwide.

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  • FDA, CDC pause Johnson & Johnson COVID-19 vaccines after blood clotting cases | KVUE

    44

    U.S. federal distribution channels, including mass vaccination sites, will pause the use of the J&J shot, and states and other providers are expected to follow.

    STORY:

    Subscribe to our channel:

    KVUE is Austin's ABC affiliate station, and has been delivering local news for Central Texans since 1971. Today it is owned by TEGNA, Inc., which reaches approximately one-third of all television households in America.

  • No Cases Of ‘Exceedingly Rare’ Blood Clots From Johnson & Johnson Vaccine In MN, But Providers Asked

    2:19

    U.S. officials have hit pause on giving people the Johnson & Johnson single dose vaccine, Caroline Cummings reports (2:18). WCCO 4 News At 6 - April 13, 2021

  • More cases of rare blood clots linked to J&J COVID vaccine

    51

    The Centers for Disease Control and Prevention reported 13 more cases of blood clots from the Johnson & Johnson vaccine.

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  • King County woman dies of blood clot after getting Johnson & Johnson vaccine

    1:23

    The woman, in her late 30's, is the first person in Washington to die as a result of blood clot caused by the J&J vaccine and only one of four known cases in the United States.

  • Doctors on the rarity of having a blood clot after Johnson & Johnson vaccine

    4:08

    State Health Secretary Mandy Cohen said there have been 242,000 doses of Johnson & Johnson given in the state and there haven't been any reports of the rare blood clots in North Carolina.

    The good news, vaccine providers have a much larger supply of Pfizer and Moderna products because they've been out longer, and the pause is only expected to last a few days.

    “Johnson & Johnson supply has been a little bit more erratic so it is not the predominant vaccine, and we don’t have concerns about significant loss of vaccine while this decision is being ironed out,” Dr. Katie Passaretti with Atrium Health said.

  • Concerns Over Johnson & Johnson Shot Increase Following Reports of Blood Clots in Bay Area Man

    2:04

    UCSF reported the first case of blood clots following the Johnson & Johnson shot in a Bay Area man. The announcement comes days after nine Bay Area health officers released a statement supporting to lift the pause on the Johnson & Johnson vaccine. Thom Jensen reports.

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  • What to do if your recently received the Johnson and Johnson vaccine?

    2:30

    The U.S. on Tuesday recommended a “pause” in using the single-dose Johnson & Johnson COVID-19 vaccine to investigate reports of rare but potentially dangerous blood clots, a development that could jeopardize the rollout of vaccines around the world.

    The Centers for Disease Control and Prevention and the Food and Drug Administration announced that they were investigating unusual clots that occurred 6 to 13 days after vaccination. The FDA commissioner said she expected the pause to last a matter of days.
    The clots occurred in veins that drain blood from the brain and occurred together with low platelets, the fragments in blood that normally form clots. All six cases were in women between the ages of 18 and 48. One person died, and all of the cases remain under investigation.

    More than 6.8 million doses of the J&J vaccine have been given in the U.S., the vast majority with no or mild side effects.

    Read more:

  • U.S. recommends pause on J&J vaccine over blood clot reports

    3:51

    U.S. health officials are recommending a 'pause' in administration of the single-dose Johnson & Johnson COVID-19 vaccine to investigate six reports of potentially dangerous blood clots.

    Read more: 

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