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Which Covid vaccine is the best? | Vaccine Effectiveness and Variants Explained

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  • Which Covid vaccine is the best? | Vaccine Effectiveness and Variants Explained

    14:00

    Which Covid vaccine is the best? Which Covid vaccine is the most effective? How do we measure vaccine effectiveness? Do Covid vaccines work against new variants? Is it possible that Covid vaccines may make things worse in the future?

    I answer all of these questions in this video. First, we compare the seven vaccines that have published phase 3 trial data as of June 2021. Those include Pfizer, Moderna, Sputnik, Johnson & Johnson, Sinopharm, and AstraZeneca. I look at the phase 3 trial data published in peer-reviewed journals.

    I compare the vaccine effectiveness between each vaccine. I also look at the differences in the phase III studies and see that the SARS-CoV-2 variants probably explain the differences in the vaccines. Each vaccine becomes less effective against variants that have more mutations, especially mutations on the spike protein, such as the E484K mutation, which can cause immune escape. Important mutations discussed include the South African variant, B.1.351, the Brazil variant, P.1, the UK variant, B.1.1.7, and the Indian variant, B.1.167.

    Finally, I explain why this matters. Countries, such as Thailand, Vietnam, and Malaysia, that have not yet had widespread Covid outbreaks may not be able to effectively use vaccines to prevent future outbreaks, as the current vaccines have substantially reduced effectiveness against the variants in those countries. I also explore the possibility that vaccines may initiate antibody-dependent enhancement, or ADE, which may make future infections worse for some people.

    0:00 Introduction
    0:53 How do we measure the effectiveness of a vaccine?
    2:13 Which Covid vaccines have published phase 3 trial data?
    3:36 How effective were Covid vaccines in phase 3 trials?
    5:48 How much do virus variants reduce vaccine efficacy?
    9:46 Not all effectiveness results can be compared
    10:30 The most vaccinated country had a Covid outbreak
    12:11 Possibility of future antibody-dependent enhancement



    For further reading:

    Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults
    A Randomized Clinical Trial |

    Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine |

    Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine |

    Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19 |

    Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia |

    Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK |

    Effectiveness of COVID-19 vaccines against the B.1.617.2 variant |

    Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants |

    Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies |

    Antibody-dependent Enhancement (ADE) and Vaccines |

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  • Coronavirus Update 127: Delta Variant and Vaccines

    18:09

    Professor Roger Seheult, MD of MedCram with an update on the effectiveness of four major vaccines against the delta variant of COVID-19: Pfizer / BioNTech, Moderna, AstraZeneca, and Johnson and Johnson Vaccine (This video was recorded on July 19, 2021).

    See the video Dr. Seheult references: 10 Tips if you Get COVID-19 here:

    Please see our most recent video on Previous Infection vs. The Delta Variant:


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 General overview of SARS-CoV-2 variants
    02:44 Characteristics of the SARS-CoV-2 delta variant (B.1.617.2)
    03:21 Preliminary data on delta variant infection rates by age & risk of severe infection
    05:14 How delta variant is affecting COVID-19 case numbers in the UK, Israel, and United States
    06:55 How do the COVID-19 vaccines stack up against delta variant? Effectiveness of Pfizer-BioNTech vaccine
    12:20 Data on the effectiveness of Moderna vaccine against the delta variant
    12:42 Data on effectiveness of Oxford-AstraZeneca vaccine against the delta variant
    13:41 Information on Johnson & Johnson vaccine effectiveness against related SARS-CoV-2 variants (no current data on delta variant)
    15:29 Vaccination rates across the United States
    17:04 What to do if you’re infected with COVID-19?


    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    5 Things To Know About the Delta Variant (Yale Medicine) |

    REACT-1 round 12 report: resurgence of SARS-CoV-2 infections in England associated with increased frequency of the Delta variant (Imperial College) |

    SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness (The Lancet) |

    Vaccines highly effective against B.1.617.2 variant after 2 doses (GOV.UK) |

    Effectiveness of COVID-19 vaccines against hospital admission with the Delta (B.1.617.2) variant (Public Health England) |

    Moderna Provides a Clinical Update on the Neutralizing Activity of its COVID-19 Vaccine on Emerging Variants Including the Delta Variant First Identified in India (Moderna) |

    How much protection COVID-19 vaccines give you against the Delta variant, according to the best available data (Business Insider) |

    The total number and mass of SARS-CoV-2 virions (NIH) |

    Covid vaccine: How many people in the UK have been vaccinated so far? (BBC News) |

    All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


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    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #SARSCoV2 #Coronavirus

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  • COVID Vaccines VS Delta Variant: State of Texas Study

    20:11

    Roger Seheult, MD of MedCram on the large real world Texas COVID 19 study on coronavirus infections and deaths by vaccination status (Pfizer vs. Moderna. vs. Johnson and Johnson vs. no vaccine). View all Dr. Seheult's videos at:

    (This video is MedCram COVID 19 update 137 and was recorded on November 15, 2021)

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    COVID-19 Cases And Deaths by Vaccination Status (Texas DSHS) |

    Coronavirus Cases (Worldometer) |

    Coronavirus Pandemic (Our World in Data) |


    All coronavirus updates are at MedCram.com (including more discussion on johnson and johnson vaccine, delta plus variant, COVID vaccine, texas department of state health services, astrazeneca vaccine second dose, the COVID delta variant, moderna, pfizer booster, vaccine rollout, blood clots, AstraZeneca second doses, moderna vaccine, and more).


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    #COVID19 #SARSCoV2 #Coronavirus

  • How effective are vaccinations against the new COVID variants? | COVID-19 Special

    12:06

    How effective are approved COVID vaccines against new forms of COVID-19? A preliminary study from Israel appears to suggest the BioNTech-Pfizer jab offers less protection against the Delta variant than previous strains - just 64%. That's a lot lower than other estimates of nearly 90%. Does this change how we fight the pandemic?
    The good news is that fully vaccinated people rarely suffer severe effects - even with the Delta variant. And despite rising cases, Israel hasn't seen a death in over two weeks. In Israel, coronvirus case numbers are creeping up again. The country has been roundly praised for its swift vaccination programme, but health officials there are proceeding with caution. With a local study suggesting the BioNTech-Pfizer jab is not as effective against the invading Delta variant as previously thought, younger Israelis are being encouraged to get vaccinated.


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    #Covid19 #DeltaVariant #CovidVaccine

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  • Covid Breakthrough Cases - Is COVID Vaccine Effective Against DELTA VARIANT?

    5:16

    Covid Breakthrough Cases - Is COVID Vaccine Effective Against DELTA VARIANT?

    COVID Vaccine breakthrough cases are popping up in the news.
    Is the Delta Variant responsible for breakthrough infections?
    Do the Vaccines still work?

    COVID cases, hospitalizations, and deaths are on the rise again. Right now, there are 162 million Americans who are fully vaccinated. According to the CDC, less than two percent of people hospitalized with COVID are vaccinated. And get this - 99.5% of people who die of COVID did not get the vaccine.

    A COVID breakthrough infection is defined as someone who tests positive for COVID, with a PCR test, at least 14 days after being fully vaccinated. Several breakthrough infections have been reported at the White House, Congress, Olympics, Major League Baseball, and more. I’ve seen people with breakthrough infections in the ICU, but not nearly as much as COVID patients in the ICU who did not get the vaccine.

    Stanford is among nearly 600 universities and colleges nationwide that have required students and faculty to be vaccinated against COVID before coming back to campus this fall. Stanford 7 Vaccinated Students Get Symptomatic COVID in a week span.

    Even before the delta variant showed up, we knew that the vaccines aren’t 100% effective. Based on the original studies, we knew that the mRNA vaccines with Pfizer and Moderna were about 95% effective at preventing severe COVID illness. This means that percentage is even smaller when you’re talking about preventing mild or asymptomatic infections. But the important thing you want to know is how effective the vaccine is at preventing severe COVID illness.

    But that 95% effectiveness was based on the original strain of COVID. Now, the scarier and more contagious Delta variant makes just about all the COVID cases in the US.

    According to this recent study, when people are infected with the Covid Delta variant, they have about 1000 times more viruses than previous versions of the covid virus. So all that viral load has the potential to overwhelm the immune system of vaccinated people.

    Another study that was just published in the NEJM also showed that the delta variant is slightly more likely to cause breakthrough infections:
    Researchers found that after two doses of the Pfizer vaccine, it gave 88% protection against symptomatic disease caused by the covid delta variant, compared to 93% against the alpha variant that was first discovered in the UK.

    Both doses of the AstraZeneca vaccine offered 67% protection against symptomatic disease. According to the company, we’re still waiting on published numbers for the Moderna vaccine, but its vaccine remained effective against the different variants.

    The Johnson & Johnson vaccine might be less effective against the Delta Covid and Lambda covid variants, but that study is yet to be published. It might be that those who received the J&J vaccine may need to get Pfizer or Moderna to protect against the new variants. So stay tuned on that.

    We know that those vaccinated have milder Covid illness compared to unvaccinated if they become infected. This is based on another study published in the NEJM that looked at more than 3,900 essential workers. It shows that fully vaccinated people are more than 90% protected against infection. Even partially vaccinated people are 81% less likely to become infected than people who haven't had been inoculated.

    Vaccinated people appear to be less likely to spread the virus to others. After one or two doses of covid vaccine, those who got breakthrough infections had 40% less virus in their bodies and were 58% less likely to have a fever. They spent two fewer days in bed compared to unvaccinated Covid patients.

    Then there is the question if you’re asymptomatic and have been vaccinated, can you still spread the virus to others?
    We know the vaccine reduces the likelihood of carrying the virus. And if you are carrying the covid virus, we know that there would otherwise be a reduced viral load. So overall, it's less likely that you are transmitting the virus if you’re asymptomatic and you’ve been vaccinated. This is why the CDC says that fully vaccinated people still need to be tested if they have symptoms and shouldn't be out in public for at least 10 days after a positive test. This is actually being studied right now in 12,000 college students who received the Moderna vaccine.

    And what about those of you who are vaccinated and are concerned about getting a breakthrough infection?
    If you were to get COVID, it's way more likely to be a milder course of the disease if you are exposed to many people, especially if they’re not vaccinated; you can wear a mask. The kind of mask to wear is another topic, but even a regular face covering would still be better at decreasing transmission compared to no mask at all.

    Doctor Mike Hansen, MD
    Internal Medicine | Pulmonary Disease | Critical Care Medicine

    #vaccine #deltavariant #covidvaccine

  • The Delta Variant: Current Evidence and Literature - COVID-19 | SARS-CoV-2 | Vaccine Efficacy

    1:11:44

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    In this lecture Professor Zach Murphy will be presenting on The Delta Variant: Current Evidence and Literature - COVID-19 | SARS-CoV-2 | Vaccine Efficacy- as of August 16, 2021.

    During this lecture we will be providing you with the most up to date evidence and literature discussing the Delta Variant and current state of the COVID-19 pandemic. We will begin this lecture by referring to the whiteboard on the current variants of concern and their pathophysiology. Next, we will take a look at current research supporting variants of concern and their relevant attributes. We will then be discussing the research defining the viral load of the Delta variant, and will then support this with evidence from a variety of reputable sources including UpToDate and the CDC. The next chapter of this lecture is a brief discussion on the overall transmissibility of the Delta variant. We look at the transmissibility or the spreadability of this Delta variant in comparison to ancestral strains and the Alpha variant. We will support these findings with current evidence on transmissibility from Public Health England and the CDC. Following this discussion, we move into the severity of the Delta variant in comparison to ancestral strains and the Alpha variant. Once again, we utilize the whiteboard and recently published articles to support our findings on the severity of the Delta variant. We will then transition into the prevalence / most affected populations in regard to the Delta variant. We support our lecture through the use of articles / research studies published by Public Health England, CDC, and The New York Times. The next chapter of our lecture is a discussion on the symptoms and treatment of COVID-19, particularly those affected by the Delta variant. We highlight the different symptoms patients are presenting with in comparison to ancestral strains and the Alpha variant. Finally, we conclude this lecture with a very important discussion on vaccine efficacy, and the potential risk of reinfection rates in regard to the Delta variant. We hope you enjoy this lecture and be sure to support us below!

    References:

    Table of Contents:
    0:00 Lab
    0:08 The Delta Variant Introduction
    0:40 Variants of Concern / Pathophysiology
    8:42 Viral Load
    10:44 Transmissibility
    14:27 Severity
    18:55 Prevalence / Populations Affected
    28:32 Symptoms associated with Delta Variant
    33:04 Treatment of COVID-19
    45:43 Vaccine Efficacy | Pfizer/BioNTech + Moderna + AstraZeneca
    1:01:14 Prevention, Masks, NPI
    1:04:20 Reinfection Rates
    1:10:09 Comment, Like, SUBSCRIBE!

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  • Vaccine Efficacy Versus Delta Variant: Real World Data

    10:08

    Roger Seheult, MD of MedCram explains new research on real world vaccine efficacy versus the delta coronavirus variant. The full video Dr. Seheult references:

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    (This video was recorded on September 23, 2021)

    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Introducing the research - How effective are approved COVID vaccines against Delta variant (United States)?
    00:59 Report from the CDC - Interim Estimates of COVID 19 Vaccine Effectiveness
    02:19 Definitions of “vaccinated,” “unvaccinated,” and “partially vaccinated”
    03:06 Dr. Seheult explains the numbers and data for all COVID vaccines in the United States
    07:56 Breakdown of efficacy by vaccine (Pzifer-BioNTech, Moderna, Janssen/Johnson & Johnson)


    LINKS / REFERENCES:

    Interim Estimates of COVID-19 Vaccine Effectiveness Against COVID-19–Associated Emergency Department or Urgent Care Clinic Encounters and Hospitalizations Among Adults During SARS-CoV-2 (Morbidity and Mortality Weekly Report) |

    MedCram Update 46:

    MedCram Update 47:


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    Video Produced by Kyle Allred


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    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #SARSCoV2 #Coronavirus

  • Coronavirus Update 125: Variants, Vaccine Uptake, Sinovac, Brazil, India, Israel

    15:01

    Professor Roger Seheult, MD of discusses the dramatic rise in COVID 19 in Brazil and India, Global Vaccine Update, The Sinovac CoronaVac Vaccine, and new research on coronavirus vaccine efficacy vs. variants in Israel, South Africa, and other locations. (This video was recorded on April 12, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Updates on COVID-19 daily new cases and daily deaths around the world
    00:30 Brazil and India emerge as global “hotspots” for COVID-19
    03:09 International vaccination campaign tracker
    04:05 Mechanism of Sinovac’s COVID-19 vaccine developed in China
    06:42 Efficacy of Sinovac vaccine on different SARS-CoV-2 variants
    08:01 COVID-19 vaccination and infection rates in Chile
    08:50 Three countries to watch carefully: Brazil, India, and Chile
    09:27 Israel among highest in the world for COVID-19 vaccine coverage
    09:48 Is Pfizer vaccine becoming less effective against South African variant in Israel?
    12:39 Serious COVID-19 cases in Israel fall below 300 for first time since December
    13:13 Could low vaccination rate be responsible for high COVID-19 death rate in Brazil?
    14:15 What to do if COVID-19 cases are surging near you


    LINKS / REFERENCES:

    Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna (MedCram) |

    If You Get COVID 19: Optimize Immune System (MedCram) |

    Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (MedCram) |

    Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (MedCram) |

    Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (MedCram) |

    Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (MedCram) |

    More Than 781 Million Shots Given: Covid-19 Tracker (Bloomberg) |

    How the Sinovac Vaccine Works (NYT) |

    Sinovac: Brazil results show Chinese vaccine 50.4% effective (BBC News) |

    Israeli data shows South African variant able to ‘break through’ Pfizer vaccine (The Times of Israel) |

    Pfizer Covid Vaccine Protects Against South African Variant, ‘Highly Effective’ Against Disease For Six Months, Updated Trial Data Shows (Forbes) |

    Pfizer and BioNTech Confirm High Efficacy and No Serious Safety Concerns... (Pfizer) |

    India bans remdesivir exports as COVID-19 cases surge (Aljazeera) |

    Chile Covid-19 vaccination drive adds to Sinovac efficacy data (S. China Morning Post) |

    Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals (medRxiv) |

    Covid-19: Why have deaths soared in Brazil? (BBC News) |

    All coronavirus updates are at MedCram.com (including more discussion on COVID variants, Sinovac, CoronaVac, COVID mutations, California variant, coronavirus variant, vaccine uptake, and more).


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    #COVID19 #SARSCoV2 #Coronavirus

  • The Delta Variant and Vaccine Protection

    7:09

    What's the deal with Covid variants? How well do the different Covid vaccines protect against the several variants? Today we'll tell you about the several variants, including the Delta variant that is prevalent in the US, and we'll talk about the studies that have looked at vaccine efficacy against these variants.

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  • Expecting data on J&J vaccines effectiveness against the delta variant

    2:36

    CNBC's Meg Tirrell on the need for masks and booster shots to battle the new Covid delta variant. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    Moderna said Tuesday its Covid-19 vaccine showed promise in a lab setting against coronavirus variants, including the highly contagious delta variant first identified in India.

    The two-dose mRNA vaccine produced neutralizing antibodies against delta as well as beta and eta, variants first found in South Africa and Nigeria, respectively, according to Moderna.

    The company said the results were based on the blood serum of eight participants one week after they received the second dose of the vaccine. The data hasn’t yet been peer-reviewed. The results, while promising, may not reflect how the vaccines actually perform in real-world scenarios against the variants.

    Shares of Moderna jumped more than 6% in intraday trading after it announced the lab results.

    “We remain committed to studying emerging variants, generating data and sharing it as it becomes available,” Moderna CEO Stephane Bancel said in a press release. “These new data are encouraging and reinforce our belief that the Moderna COVID-19 Vaccine should remain protective against newly detected variants.”

    Moderna’s update comes days after World Health Organization officials urged fully vaccinated people to continue to wear masks, social distance and practice other pandemic safety measures as delta spreads rapidly across the globe.

    It also comes the same day Moderna said its vaccine was authorized for use in India, where the delta variant is thought to be behind the large outbreak there.

    Delta, now in at least 92 countries, including the United States, is expected to become the dominant variant of the disease worldwide. In the U.S., the prevalence of the strain is doubling about every two weeks.

    WHO officials said Friday they are asking fully vaccinated people to continue to “play it safe” because a large portion of the world remains unvaccinated and highly contagious variants, like delta, are spreading in many countries, spurring outbreaks.

    The comments were a departure from the Centers for Disease Control and Prevention, which has said fully vaccinated Americans can go maskless in most settings.

    “People cannot feel safe just because they had the two doses. They still need to protect themselves,” Dr. Mariangela Simao, WHO assistant director-general for access to medicines and health products, said during a news briefing.

    Authorized vaccines from Moderna, Pfizer-BioNTech and Johnson & Johnson have demonstrated to be highly effective in preventing Covid, especially against severe disease and death.

    Some variants, including delta, have shown to make the vaccines slightly less effective and WHO officials said they worry vaccinated individuals could become part of transmission chains.

    The Wall Street Journal reported Friday that about half of adults infected in an outbreak of the delta variant in Israel were fully vaccinated with the Pfizer vaccine, prompting the government there to reimpose an indoor mask requirement and other measures.

    In the U.S., President Joe Biden warned that unvaccinated people are especially at risk of becoming infected with delta.

    He said Covid deaths nationwide will continue to rise due to the spread of the “dangerous” variant, calling it a “serious concern.”

    “Six hundred thousand-plus Americans have died, and with this delta variant you know there’s going to be others as well. You know it’s going to happen. We’ve got to get young people vaccinated,” Biden said Thursday at a community center in Raleigh, North Carolina.

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  • Coronavirus Update 123: COVID 19 Vaccines vs. Variants

    10:42

    How well will COVID-19 vaccines work against the coronavirus variants first discovered in the UK, South Africa, and Brazil? Dr. Seheult discusses the research we have so far on SARS CoV 2 mutations. (This video was recorded on February 23, 2021).

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


    LINKS / REFERENCES:

    COVID: UK variant spreading rapidly in Germany (DW) |

    Germany: Schools reopen for younger children amid rising COVID infections (DW) |

    Where schools are reopening in the US (CNN) |

    Adapted booster vaccines in the works (Medical News Today) |

    Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera (Science) |

    Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera (Cell) |

    mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants (bioRxiv) |

    Moderna COVID-19 Vaccine Retains Neutralizing Activity Against Emerging Variants First Identified in the U.K. and the Republic of South Africa (Moderna) |


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    RECENT PREVIOUS COVID-19 UPDATES:

    Please visit MedCram.com for the full series:
    - Coronavirus Update 122: The Research So Far on COVID-19 and Vaccines vs. Pregnancy
    - Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna
    - Coronavirus Update 120: Anticoagulants (Blood Thinners) Improve Hospital Outcomes (Full Dose)
    - Coronavirus Update 119: Pfizer BioNTech COVID Vaccine (Clinical Considerations)
    - Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Coronavirus (SARS CoV 2)
    - Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna mRNA vaccines)

    All coronavirus updates are at MedCram.com (including more discussion on COVID variants, COVID mutations, and more).

    We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website.


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    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
    #COVID19 #SARSCoV2

  • Pfizer developing Covid-19 vaccine booster targeting Delta variant

    3:15

    CNBC's Meg Tirrell reports on Pfizer's update regarding its Covid-19 booster shot.

  • The Delta Variant, Vaccine Effectiveness and Development of Intranasal COVID-19 Vaccines

    10:37

    How dangerous is the Delta variant? Do vaccines remain protective against Delta? Why are fully vaccinated people still transmitting the virus? What can be done to slow viral evolution?

    In this race for survival of the fittest, Delta, which the World Health Organization has called the “fastest and fittest variant so far,” has given the virus an edge. Thanks to a series of mutations in the spike protein, the portion of the virus that binds to human ACE2 receptors and mediates viral entry, Delta is 40-60% more transmissible than Alpha and almost twice as transmissible as the original Wuhan strain.

    The key is to get ahead of the natural selection that’s occurring. If we want to stop SARS-CoV-2 from continuing to evolve and spread, we need to simultaneously reduce case numbers and increase immunity.

    Takeaways from today’s session about the SARS-CoV-2 Delta variant, vaccines and mucosal immunity:

    - The Delta variant is 40-60% more transmissible than Alpha and almost twice as transmissible as the original Wuhan strain.

    - Vaccines remain highly effective at preventing hospitalization and death from Delta infection.
    Data indicate that vaccinated individuals may still be able to transmit the virus.

    - This is due, in part, to the generation of insufficient mucosal immunity via systemic injection to remain protective long term.

    - Mucosal routes of immunization are under investigation, with a number of intranasal vaccines entering clinical trial.

    In combination, vaccination and masking can reduce the risk of severe disease, slow transmission and reduce the evolution of SARS-CoV-2.

    Sources:
















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  • Coronavirus Variants and Vaccines

    11:00

    As more people get vaccinated against COVID-19 every day in the US and with case numbers declining, many have started feeling optimistic that life could return to normal. But the spread of SARS-CoV-2 variants around the globe could threaten that possibility if they blunt the effectiveness of available vaccines. This video reviews what we know as of April 2021 about coronavirus variants and vaccines, and implications for public health going forward.

    For links to related articles and multimedia, visit Links to source references are embedded in the transcript.

    Originally published April 7, 2021.

    0:00 Viral evolution
    1:34 Neutralizing antibodies
    2:21 Testing variants against vaccine serum
    3:06 B.1.1.7
    3:32 B.1.351
    4:14 P.1 and B.1.427/B.1.429
    4:40 Limitations to laboratory testing
    5:27 On-the-ground data
    5:54 Data from clinical trials
    6:02 AstraZeneca
    6:24 Novavax
    6:54 Janssen/Johnson & Johnson
    7:43 Steps going forward
    8:36 Vaccine strategies: booster shots, bivalent vaccines
    9:43 Best way to reduce risk of variants

  • Delta Variant Versus Previous COVID 19 Infection vs. Vaccines

    16:18

    Roger Seheult, MD of MedCram explains how natural immunity (from a previous COVID-19 infection) compares with vaccines (Pfizer, Moderna, AstraZeneca) VS. the Delta coronavirus variant. (This video was recorded on July 24, 2021).

    Correction: Strasbourg is in France (near the German border), not in Germany.

    TOPICS IN THIS VIDEO INCLUDE:

    00:00 Is natural immunity from previous COVID-19 infection strong enough against Delta variant?
    00:32 Research study of 50,000+ patients from the Cleveland Clinic
    03:07 Qatar airport study shows previous infection with SARS-CoV gives reasonable immunity against reinfection
    05:46 UK data suggests low risk of COVID-19 reinfection among population
    07:04 Study on antibody response effectiveness (from vaccines and natural infection) at neutralizing several COVID-19 variants, including Delta
    13:33 Monoclonal antibodies shown to have little effectiveness against Delta variant
    14:31 Patients urged to get both doses of Pfizer or Moderna, especially for protection against Delta variant
    14:59 MedCram resources for medical providers treating COVID-19 patients and the case for lung ultrasounds

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    See the video Dr. Seheult references about Lung Ultrasound in COVID 19:

    LINKS / REFERENCES:

    Can You Get Delta Variant if You Already Had COVID-19? (Healthline) |

    Necessity of COVID-19 vaccination in previously infected individuals (medRxiv) |

    Associations of Vaccination and of Prior Infection With Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar (JAMA) |

    New national surveillance of possible COVID-19 reinfection, published by PHE (GOV.UK) |

    Study highlights need for full Covid vaccination to protect against Delta variant (STAT) |

    All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


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    #COVID19 #Deltavariant #Coronavirus

  • Delta Variant: Why the New Covid is worse | Vaccines, Virulence, and Transmissibility Explained

    14:12

    Description: The Delta variant of SARS-CoV-2, the virus that causes Covid-19, has taken over the world, now accounting for 73% of global cases and rising. Around the world, from the UK to Indonesia to the US, Delta now dominates, making up 99% of the virus circulating in those countries. The US CDC, the WHO, and Public Health England are sounding the alarm on Delta.

    Why are epidemiologists alarmed about the Delta variant? Why are experts warning about Delta? In today’s video, I’m going to review the latest scientific literature to answer that question. In doing so, I’ll address five questions: (1) What is the delta variant? (2) Is delta more infectious or transmissible? (3) Does delta cause more severe illness or death? (4) Are vaccines less effective against delta? (5) And, how does delta change public health policy?

    It’s everything you need to know about Delta with evidence-based science explained!

    Shocking data from a leaked internal CDC report shows that breakthrough infections are not rare and that vaccinated individuals can harbor as much virus as unvaccinated people. The good news is that vaccines can still reduce the risk of hospitalizations and death, even against the delta variant.

    Covid is here to stay. New variants, including the lambda variant in Peru and a new variant called 21H in Colombia, are coming. We still need non-pharmaceutical interventions, including masks and limiting time in crowded indoor spaces. Finally, delta may cause countries like China, Australia, and New Zealand to abandon their Covid strategies.

    0:00 Introduction
    1:13 What is the Delta Variant?
    3:42 Is the Delta Variant more transmissible?
    5:55 Does the Delta Variant cause more severe disease?
    7:52 Are vaccines effective against the Delta Variant?
    11:21 What does this mean for public health policy?




    ****Links to studies and sources of data:

    SARS-CoV-2 variants of concern and variants under investigation in England, Public Health England Technical briefing 19 |

    SARS-CoV-2 Shared Mutations |

    Implications of the Novel Mutations in the SARS-CoV-2 Genome for Transmission, Disease Severity, and the Vaccine Development |

    Recent progress on the mutations of SARS-CoV-2 spike protein and suggestions for prevention and controlling of the pandemic |

    SARS-CoV-2 variants, spike mutations and immune escape | s41579-021-00573-0

    Clinical and Virological Features of SARS-CoV-2 Variants of Concern: A Retrospective Cohort Study Comparing B.1.1.7 (Alpha), B.1.315 (Beta), and B.1.617.2 (Delta) |

    Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant |

    SARS-CoV-2 B.1.617.2 Delta variant emergence and vaccine breakthrough |

    Guidance for Implementing COVID-19 Prevention Strategies in the Context of Varying Community Transmission Levels and Vaccination Coverage |

    Effectiveness of COVID-19 vaccines against variants of concern in Ontario, Canada |

    SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness |

    Progressive Increase in Virulence of Novel SARS-CoV-2 Variants in Ontario, Canada |

    Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 2021 |

  • Do COVID-19 vaccines protect against variants? Also, what is a variant?

    4:01

    Dr. Seema Yasmin answers your questions about the COVID-19 vaccine and coronavirus variants: Should I get a COVID-19 vaccine if there are new variants? What is a variant? Are COVID-19 vaccines effective against new variants? Should I wait to get a COVID-19 vaccine while the variants are being studied?

    -------------------

    Viral Facts is a regular series brought to you by the Stanford Center for Health Education and its Digital Medic initiative. We are a team of clinicians, global health researchers, educational experts, and designers who translate complex health information into engaging learning experiences.

    Note: All of our content is produced using the best evidence available at the time of publishing. We will do our best to update content as information evolves, but please visit the Center for Disease Control and Prevention’s website for the most up-to-date information on COVID-19:

    Dr. Seema Yasmin is an Emmy-award winning journalist, medical doctor and author of four books. She trained in medicine at the University of Cambridge and in journalism at the University of Toronto. Dr. Yasmin is director of the Stanford Health Communication Initiative. She served as an officer in the Epidemic Intelligence Service at the U.S. Centers for Disease Control and Prevention and is a medical analyst for CNN.

    Do you have questions about COVID-19 that you'd like answered in a future episode? Reach out to us through Twitter, Facebook, or our website:

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  • Fact check: Do COVID-19 vaccines protect against the delta variant? | DW News

    6:04

    Worldwide, some people died of the delta variant despite being fully vaccinated. Is the COVID-19 vaccination no longer sufficient? A look at the facts shows: Yes, complete vaccinations are still the best protection you can get against delta.

    Key sources:








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    #CovidVaccine #DeltaVariant #FactChecking

  • COVID-19 Delta Variant - Masks for Fully Vaccinated People Explained

    4:00

    Dr. Stuart Cohen, Director of Hospital Epidemiology and Infection Control at UC Davis Medical Center, explains why the COVID-19 Delta variant is more easily transmitted than previous variants, how masks should still play a role in keeping you safe (even if you are vaccinated) and why getting a COVID-19 vaccine is vital for preventing future variants of the novel coronavirus.

    Learn more about Delta and masking:
    For the latest information and resources on COVID-19, visit
    See the latest news from UC Davis Health:

    #covid19 #deltavariant #coronavirus #delta #ucdavis

  • Delta Plus Variant : Lancet Data Raises Alarm Over Vaccine Efficacy

    3:50

    As the Delta plus variants becomes the cause of panic, the Lancet data suggests that Covishiled provides slightly less protection against the Delta variant. Watch the full report.

    #Covid #DeltaVariant #Vaccine #IndiaToday

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  • Johnson & Johnson vaccine effective against COVID-19 variants l GMA

    3:49

    New data shows that the single-dose inoculation, which could get FDA emergency use authorization by Friday night, may be 100% effective at preventing hospitalization and death from the virus.

    LEARN MORE:
    What the latest Johnson & Johnson COVID vaccine data really means:

    #ABCNews #JohnsonandJohnson #COVIDVaccine #COVID19

  • How Protected Are Vaccinated Americans Against The Delta Variant?

    4:38

    With life starting to get back to normal in some cities across the United States, the Delta variant of COVID-19 could become the dominant strain in the country. In this week’s Sunday Focus, NBC News’ senior medical correspondent Dr. John Torres reports that the key to stopping COVID-19 and all its variants is to get vaccinated. Some 65% of Americans have received at least one shot.

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  • WHO chief criticises Pfizer, Moderna over vaccine strategy as Delta variant drives up Covid cases

    4:43

    World Health Organisation Director General Tedros Adhanom Ghebreyesus warned that Covid-19 cases and related deaths are rising again after some respite. His warning coincided with increased public movement in India following relaxation of restrictions. Ghebreyesus also criticised vaccine-makers Pfizer and Moderna for prioritising jabs for countries with comparatively high vaccine coverage while middle and low-income countries suffer. Watch the full video for more.

    #Covid #WHO #Vaccine

  • Covid-19: Can vaccines keep up with variants? | The Economist

    6:32

    The race between covid-19 vaccines and variants is on. Alok Jha, The Economist’s science correspondent, and Natasha Loder, health policy editor, discuss what this means for the future

    Read more of our coverage on coronavirus:

    Listen to our daily podcast, Gamechangers, on mRNA technology:

    Listen to “The Jab” podcast from Economist Radio:

    Watch our film about mandatory vaccines:

    Which countries are considering a booster jab?

    Why are covid variants named using the Greek alphabet?

    Can vaccines help solve environmental issues?

    Why is the Delta variant the most dangerous mutation yet?

    What’s Britain’s strategy for mass vaccination?

    Where will you need proof of vaccination?

    How the pandemic has brought re-examination of intellectual-property rights:

    Why are the unvaccinated at risk?

    Which vaccine is the most widely accepted for international travel?

  • New questions about COVID-19 vaccine efficacy against variant, more mask mandates l GMA

    4:17

    Las Vegas has joined Los Angeles in returning to mask mandates in public indoor places as new COVID-19 hotspots pop up across the country.

    LEARN MORE:
    Why breakthrough COVID-19 infections don't mean the vaccine isn't working:


    #ABCNews #LasVegas #LosAngeles #MaskMandate #COVID19

  • As cases surge, Israel says Pfizer vaccine less effective against Delta variant of Covid

    1:54

    The Ministry of Health of Israel said that it has witnessed the efficacy rate of Pfizer’s vaccine drop to 64% against the Delta variant of Covid. However, vaccines were still effective in preventing hospitalization and sever illness. Israel has had one of the most successful inoculation drives in the world with 55% of its population completely vaccinated. The country had removed all Covid curbs on June 1 but according to reports, due to a recent surge in cases, it is mulling over imposing restrictions again. Watch the full video for more details.

  • J&J vaccine much less effective against delta variant: New study

    1:26

    An NYU lab study suggests that one dose of the Johnson & Johnson vaccine is significantly less effective against the delta variant. The study confirms that Moderna and Pfizer's covid vaccines are still effective against the delta strain. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    Intensive-care unit and lung doctor Dr. Vin Gupta told CNBC that he’s already encouraging patients who received the single-shot Johnson & Johnson Covid vaccine to get a Pfizer or Moderna booster shot amid the dramatic increase in delta variant cases across the U.S.

    Gupta, a professor at the University of Washington’s Institute for Health Metrics and Evaluation, told “The News with Shepard Smith” that “AstraZeneca, when combined with a Pfizer or Moderna booster, is showing tremendous levels of protection against delta, in terms of the antibody levels that are generated in patients.”

    “I do think that those one-shot J&Jer’s should be given the opportunity, while we complete our clinical trial ... I’m already telling my patients to do it, if they can get access to it.”

    Gupta’s comments come on the heels of a new study from a lab at New York University Tuesday that raises serious questions about the effectiveness of J&J’s single-dose vaccine against the highly contagious delta variant. The NYU study is not yet peer reviewed, but found that the antibody levels in those who received the J&J shot may be low enough to be less protective.

    CNBC correspondent Meg Tirrell interviewed the lead author of the study, Dr. Ned Landau, who told her that the study suggests, “one should at least consider a second vaccination, a second shot” with the J&J vaccine, either of the same vaccine, or one from Pfizer or Moderna.

    J&J told CNBC that its own data showed the vaccine “generated strong, persistent activity against the delta variant and other highly prevalent variants.”

    The Centers for Disease Control and Prevention told CNBC that it stands by its statement earlier this month about boosters that “Americans who have been fully vaccinated do not need a booster at this time.”

    Gupta furthered the case for administering a booster shot when he told host Shepard Smith that his “definition of fully vaccinated is two doses of a vaccine.”

    Smith asked for clarification on whether Gupta considers the nearly 13 million Americans who received the J&J dose were actually fully vaccinated.

    “I think you’re protected, likely from the hospital and severe outcomes from say, the delta variant, based on what data we do have,” Gupta said. “I do not think you have the same level of protection to transmit the virus than somebody who received two doses of the vaccine like Pfizer or Moderna. I think that is pretty clear at this point.”

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  • WHOs Science in 5 on COVID-19: Delta Variant And Vaccines

    4:13

    Do the current batch of approved vaccines protect us from the Delta variant? What is the level of protection? If you can still get infected even after being fully vaccinated, then why should we vaccinate? WHO's Chief Scientist Dr Soumya Swaminathan explains in Science in 5. [Credit: World Health Organisation -

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  • Delta Variant: Top 10 COVID Questions and How to Prepare

    22:27

    A coronavirus (COVID-19) variant has become dominant in the USA and Roger Seheult, MD of MedCram responds to 10 common questions including:

    00:00 If someone is fully vaccinated or already had COVID, how worried should they be about the Delta Variant?
    02:16 Should we be getting booster COVID vaccine doses?
    05:36 Will there continue to be more variants, perhaps even variants more challenging that the Delta variant?
    07:24 Is Long COVID occurring in the fully vaccinated?
    08:26 When is this surge going to peak? Can we learn from other countries?
    12:52 Are more children getting hospitalized with COVID 19 Delta variant?
    14:03 What happens when school starts?
    16:06 Have treatment and testing strategies changed for Delta variant?
    19:45 What can we do to protect ourselves and our communities from the coronavirus Delta variant and future COVID mutations?

    This video was recorded on August 6, 2021

    Roger Seheult, MD is the co-founder and lead professor at
    He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

    Interviewer: Kyle Allred, Physician Assistant, Producer, and Co-Founder of MedCram.com

    LINKS / REFERENCES:

    COVID-19 Ventilator Course:

    Lung Ultrasound in COVID 19:

    Delta Variant vs. Previous COVID-19 Infection | MedCram:

    Delta Variant vs. Vaccines | MedCram:

    10 Tips If You Get COVID-19 | MedCram:

    Worldometer:

    Covid-19 Breakthrough Infections in Vaccinated Health Care Workers
    List of authors | NEJM:



    WHO calls for halting COVID-19 vaccine boosters in favor of unvaccinated |

    AMA Physicians Survey |

    Covid-19 Breakthrough Infections in Vaccinated Health Care Workers | NEJM:

    Six Month Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine | MedRxiv:

    The key numbers from the CDC’s new assessment of the delta variant | WP:

    All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, Delta variant in US, Delta variant Canada, and more).


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    MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


    MEDIA CONTACT:

    Media Contact: customers@medcram.com
    Media contact info:

    Video Produced by Kyle Allred


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    DISCLAIMER:

    MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

    #COVID19 #Deltavariant #Coronavirus

  • Does the COVID-19 Vaccine Protect Against Variants?

    48

    For more information on the latest COVID-19 variants and mutations, please visit

    The COVID-19 vaccines have protection against every variant, so far. Even with more breakthrough cases reported with the delta variant, the vaccines are effective at preventing serious illness and death.

    #CovidUpdate #CovidVarient #Covid19Vaccine

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  • The effectiveness of Covid-19 vaccines against variants

    4:51

    After a recent study was released about the B.1.351 variant's impact on the effectiveness of Covid-19 vaccines, Geoffrey Porges, Director of Therapeutics Research and Senior Biotechnology Analyst at SVB Leerink, joins Worldwide Exchange to discuss the implications. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

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  • Vaccines Will Be Less Effective Against Covid Variants: Johns Hopkins

    1:45

    Jul.06 -- Johns Hopkins International Vaccine Access Center Executive Director Dr. William Moss talks about the effectiveness of Covid vaccines against variants. He speaks on “Bloomberg Markets.” The Bloomberg School of Public Health is supported by Michael R. Bloomberg, founder and majority owner of Bloomberg LP, the parent company of Bloomberg News.

  • Which Covid-19 vaccine is the best? variants of concern! 2021

    32:32

    Which Covid-19 (corona) vaccine is the best? variants of concern! (spoiler, VOC are less effective) 2021
    00:00 intro
    03:58 types of covid-19 vaccine
    08:17 vaccine induce immunity cell mediated and antibody mediated immunity
    18:58 efficacy
    20:20 calculating efficacy
    23:13 head to head clinical trial comparison
    26:31 types of major variants
    29:08 conclusion

    References
    A study published in the Lancet found a single dose of Covid-19 vaccine wasn't enough, but after the second dose, the Pfizer-BioNTech provided 79% protection from the Delta variant. That compares with 92% protection against the Alpha variant



    Comparison of two highly-effective mRNA vaccines for COVID-19
    during periods of Alpha and Delta variant prevalence



    Both vaccines are still highly effective against severe disease from the delta variant COVID-19, the study authors stressed. However, Moderna was found to be, on average, 76% effective against infection from the delta variant compared to Pfizer, which was 42% effective against infection from the variant.

    CDC Latest Data: Stratification by Age and Vaccine Type
    10/18/21

    Unvax are about 6x more likely to test positive and 11x more likely to die from Covid compared to those vaccinated. Data extends from April - End of August. Partially vaccinated were excluded. Includes 16 health departments that regularly provide this data, representing 30% of US pop.
    Some vaccine differences were noted (see Figures):

    Case Rates:
    Unvax: 737/100k
    J&J: 172/100k
    Pfizer: 136/100k
    Moderna: 86/100k

    Death Rates:
    Unvax: 13/100k
    J&J: 3/100k
    Pfizer: 1.4/100k
    Moderna: 0.69/100k

    Conclusions: vaccines reduce chance of testing positive (cases) and deaths. They do so with differential effectiveness.

  • EMA: Pfizer, Moderna vaccines effective against COVID-19 variants | COVID-19 Vaccines | Latest News

    5:20

    The EU’S drug agency has approved the storage of the Pfizer-BioNTech coronavirus vaccine in fridges for up to a month. The European Medicines Agency said this could improve the flexibility in countries’ vaccine rollout.

    #EMA #COVID19Vaccines #WorldNews

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  • Moderna and Pfizer COVID vaccines shown to be effective against variants

    4:16

    New data shows both the Moderna and Pfizer vaccines have promising results against COVID-19 variants. John Moore, a professor of microbiology and immunology at Weill Cornell Medical College, joins CBSN's Tanya Rivero for more on the efficacy of COVID vaccines.

    CBSN is CBS News’ 24/7 digital streaming news service featuring live, anchored coverage available for free across all platforms. Launched in November 2014, the service is a premier destination for breaking news and original storytelling from the deep bench of CBS News correspondents and reporters. CBSN features the top stories of the day as well as deep dives into key issues facing the nation and the world. CBSN has also expanded to launch local news streaming services in major markets across the country. CBSN is currently available on CBSNews.com and the CBS News app across more than 20 platforms, as well as the Paramount+ subscription service.

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  • Covid vaccines still effective against Delta variant - BBC News

    4:41

    Having two doses of Covid vaccine remains the best way to protect against the Delta variant, first identified in India and now dominant in the UK.

    The Oxford-AstraZeneca jab, though initially less effective, offers the same high protection as the Pfizer-BioNTech after four to five months, the largest study of its kind suggests.

    But neither is as effective as it is against the Alpha variant, responsible for most UK infections last winter. There is insufficient data for Moderna. But researchers believe it almost certainly at least as good as the others.

    They analysed two and a half million tests results from 743,526 participants in the UK's Covid-19 household-infection survey - led by Oxford University and the Office for National Statistics.

    Please subscribe HERE

    #BBCNews

  • Vaccine efficacy against Covid-19 variants in India

    3:15

    A new scientific analysis has found that two doses of Covid-19 vaccines are highly effective in preventing hospitalisation due to B.1.617.2, now known as the Delta variant.

    #Deltavariant #Covid-19 #Indianvariant #covid19vaccines #astrazeneca #pfizer #covishield #deltavariant

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  • Johnson & Johnson Says Vaccine Effective Against Delta Variant

    1:48

    Johnson & Johnson says their own study proves its Covid-19 vaccine is effective against the delta variant, which now accounts for a quarter of all new cases. » Subscribe to NBC News:
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    #Vaccines #Delta #J&J

    Johnson & Johnson Says Vaccine Effective Against Delta Variant

  • Effectiveness of COVID-19 Vaccines Against the B.1.617.2 Variant of Concern

    1:29

  • AstraZeneca, Pfizer vaccines effective against Delta COVID-19 variants: study

    51

    COVID-19 vaccines made by AstraZeneca and the Pfizer-BioNTech alliance remain broadly effective against Delta and Kappa variants of the COVID-19 causing virus, which were first identified in India, according to a scientific study, underpinning a continued push to deliver the shots.

    #Pfizer #Astrazeneca #Deltavariant #COVID #Coronavirus #News #Reuters

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  • COVID-19 Vaccines and Variants Explained

    5:22

    Over 50 million Americans have been fully vaccinated against COVID-19, yet even as more and more people roll up their sleeves, many questions still remain about how effective the vaccines will be against emerging COVID variants. Will the current crop of vaccines protect us against those new threats? How many people need to be vaccinated before we can achieve herd immunity? Will we need booster shots to keep new variants at bay?

    In this video, Boston University public health experts Davidson Hamer and Cassandra Pierre discuss the future of the pandemic, and how the tension between vaccines vs variants will shape its trajectory.

    #CovidVaccine #CovidVaccineExplained #Covid19

  • What we know about COVID-19 vaccine effectiveness against variants

    2:11

    Dr. Jen Ashton answers viewers’ latest coronavirus questions.

  • How effective are COVID-19 vaccines against variants?

    2:13

    Dr. Darien Sutton shares some encouraging news about the Pfizer and Moderna vaccines’ efficacy against the delta variant.

  • Pfizer vaccine neutralizes Brazil and U.K. variants of Covid-19: Lab study

    5:10

    There's new optimism surrounding Pfizer's coronavirus vaccine's ability to fight against the rapidly spreading new variants. CNBC's Meg Tirrell reports. For access to live and exclusive video from CNBC subscribe to CNBC PRO:

    New more contagious variants of the coronavirus are being investigated in the United States, raising questions about whether the Covid vaccines currently in use will provide protection against mutations.

    There are multiple more contagious variants emerging around the globe, in the United Kingdom, South Africa and Brazil. In the U.S., variants from New York City and California have been identified.

    So far, studies suggest that the vaccines currently in use can recognize the emerging variants — but they don’t provide as much protection against these new strains. The variant from South Africa, for example, reduced Pfizer-BioNTech’s antibody protection by two-thirds, according to a February study. Moderna’s neutralizing antibodies dropped six-fold with the South Africa variant.

    (There are several reasons the antibodies generated after receiving a vaccine might recognize a variant but not fight it as well. For instance, antibodies protect you by attaching to each individual spike protein on the surface of the coronavirus, which prevents it from infecting your cell. If a variant produces many times more virus, the antibodies may not be able to attach to all those virus pieces as precisely or efficiently.)

    But boosters and new versions of vaccines that target the variants are already being explored.

    The three vaccines that have been authorized by the Food and Drug Administration for emergency use from Moderna, Pfizer-BioNTech and Johnson & Johnson work in different ways, and therefore have different approaches to handling variants.

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  • Vaccine efficacy uncertain as coronavirus variants spread | DW News

    15:30

    Is the coronavirus mutating its way around the vaccines? We take a look at the real threat of the viral variants & the efficacy of the vaccines we have now.

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    #Coronavirus #Vaccine #Variants

  • Pfizer vaccine stats against delta variant

    2:20

    Recent data from Israel found the Pfizer vaccine was 64% effective in preventing symptomatic COVID cases and 93% effective in preventing serious illness and hospitalization.

  • Is the Pfizer booster shot necessary to beat the delta variant? An expert weighs in

    5:57

    Pfizer's recent push to add a booster shot to its COVID-19 vaccination protocol seems to be at odds with what many people understood about the drug's effectiveness. And, as William Brangham reports, it has also prompted real concern among healthcare professionals. Dr. Kirsten Bibbins-Domingo, a professor of epidemiology and biostatistics at the University of California joins us to discuss.

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  • COVID19: Are Vaccines Effective Against Delta Plus Variant? | NewsMo

    1:21

    Delta Plus variant is the growing cause of concern for India. While vaccines offer a very high level of protection against hospitalisation and the severity of the disease, can they evade this new variant as well? Watch to find out.

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  • AstraZeneca vaccine effective against Brazil variant: Study | COVID vaccine update | English News

    1:38

    Preliminary data from a study conducted at the University of Oxford indicates that the Covid-19 vaccine developed by AstraZeneca PLC is effective against the P1

    #AstraZeneca #COVIDvaccine #EnglishNews

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  • Are vaccines effective against Indian variant of Covid-19? Find out

    2:51

    The coronavirus variant B.1.617 first identified in India last year has been classified by the World Health Organization (WHO )as a variant of global concern, with some preliminary studies showing that it spreads more easily, But are vaccines effective against this variant? Watch this video to find out.

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